Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,4-Dihydro-1H-quinazolin-2-one is a compound that belongs to the class of thp-1 cells. It has been shown to inhibit the proliferation of cancer cells in vitro. 3,4-Dihydro-1H-quinazolin-2-one inhibits the production of oleanonic acid and other prostaglandins by inhibiting cyclooxygenase and lipoxygenase activities. This compound is stable in hydrochloric acid, which may be used for chemical synthesis. The flow system is a technique for synthesizing polymers with high molecular weight by polymerization at elevated temperature and pressure. 3,4-Dihydro-1H-quinazolin-2-one is minimally toxic to mammals and can be easily synthesized using palladium catalysis with amino acids as coupling partners. Biological studies have shown that it has heteroatomic properties and reacts through an S N 2 mechanism</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Trifluoromethyl)-1H-imidazole is a petrochemical that has a trifluoromethyl group. The imidazoles are thermally activated and pentafluoroethyl, ethane, reactive, hydrophobic, and their analogs react with ethyl bromoacetate to form an ether linkage. 2-(Trifluoromethyl)-1H-imidazole is used in the synthesis of products such as the linker for reaction mechanism with trifluoroacetyl.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(2-Hydroxyethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one is an impurity in the drug paliperidone. It is a pyridinic acid derivative and has been used as a ligand in X-ray crystallography to identify protein structures. 3-(2-Hydroxyethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4 one is also known to have high detection sensitivity and can be used to analyze ammonium formate. This impurity has been detected in the urine of patients taking paliperidone extended release tablets. To remove this impurity from the drug paliperidone, it must be purified by liquid chromatography or liquid chromatography with high performance liquid chromatography (</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Benzyl-6-chloro-1H,2H,3H-pyrrolo[3,2-c]pyridine-7-carbonitrile is an alkoxy compound that has been shown to react with amines and halogen to form pyridines. The compound also reacts with hydroxy groups and nucleophilic residues to form alkoxy groups. This reaction is catalyzed by hydroxy groups or a base such as sodium hydroxide or potassium hydroxide. 1-Benzyl-6-chloro-1H,2H,3H-pyrrolo[3,2-c]pyridine-7-carbonitrile can be used in the synthesis of polymers and plastics. It can also be used as a precursor for the synthesis of other compounds.</p>

<p>Encainide is a class I antiarrhythmic drug that belongs to the group of class Ia drugs and inhibits the fast sodium channel. It slows the heart rate and decreases conduction velocity in cardiac tissue. Encainide has been shown to be effective against tachycardia and ventricular arrhythmias. It has been shown to have a stable dose-response curve as well as no known drug interactions. Encainide has also been shown to improve cardiac function by inhibiting the activity of beta-receptors in cardiac muscle, which may lead to increased contractility, improved relaxation, and increased blood flow. Encainide is mainly used for the treatment of arrhythmias in patients with certain heart conditions, such as papillary muscle dysfunction or cardiomyopathy.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,3-Dimethyl-1,4-dioxan-2-one (DMDO) is a chiral compound that is used in organic synthesis as a chiral auxiliary. This molecule has been shown to be useful for the stereoselective polymerization of lactones, enolates, amides and aldehydes. DMDO has also been investigated for its ability to form spindle-like polymers with glycolide and optical activity. 3,3-Dimethyl-1,4-dioxan-2-one is soluble in common organic solvents such as chloroform and dichloromethane at room temperature and can be used for the preparation of microparticles with a diameter up to 50 µm. The high yield of this compound makes it an attractive alternative to other synthetic methods.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(6-Amino-1H-purin-8-yl)amino]ethan-1-ol (6APA) is a prodrug that is metabolized by the liver to 6-mercaptopurine (6MP). It is an antiinflammatory drug that has been shown to suppress collagen synthesis and inhibit the activity of proteases. 6APA is also used as a diagnostic agent for systemic diseases, such as reactive arthritis and systemic lupus erythematosus. This compound can be used in the treatment of inflammatory diseases, such as rheumatoid arthritis and Crohn's disease, due to its ability to inhibit the production of inflammatory compounds. The drug binds to affinity ligands which are associated with various proteins, including collagen. This binding prevents the formation of new proteins, which leads to cell death by inhibiting protein synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(1H-1,3-Benzodiazol-2-yl)-1-phenylethanone is an unsymmetrical phenacyl chloride that is used in the synthesis of drugs. The generation of acidolysis products and the formation of active methylene compounds are catalyzed by 2-(1H-1,3-benzodiazol-2-yl)-1-phenylethanone. This compound is also used for the preparation of chlorides and methylhydrazones. Preparative methods for this compound involve thionyl chloride, hydrochloric acid, and phenylhydrazone.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>