Building Blocks

<p>Versatile small molecule scaffold</p>

<p>3-Pyridin-4-ylaniline is a chemotherapeutic that can be used to treat cancer. It has been shown to inhibit the growth of tumors in mice with leukemia, and it inhibits the replication of human cancer cells in vitro. The chemical structure of 3-Pyridin-4-ylaniline includes a nitrogen atom connected to an aromatic ring. The nitrogen atom is also bonded to two ligands, which are pyridazine and carbonyl groups. 3-Pyridin-4-ylaniline binds to purines, a type of molecule that are found in DNA and RNA. This binding prevents the incorporation of purines into DNA and inhibits cancer cell proliferation by blocking DNA synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>3,5-Dimethylphenyl Isothiocyanate is a sulfur analogue that has the same molecular weight and chemical properties as 3,5-dimethylthiophenol. It is used to derivatize organic compounds with thiol groups via reactions with aliphatic, aromatic, and heterocyclic systems. The enantiomer of this compound is called S-(+)-3,5-dimethylphenyl isothiocyanate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylbenzamide oxime is a chemical compound that has the chemical formula C6H5N3O. It is used as a reagent in organic synthesis. 3-Methylbenzamide oxime also acts as a silver-containing oxidant, which can be used to generate hydrogen peroxide or silver oxide.</p>

<p>N-Hydroxymethyl-3-(trifluoromethyl)benzamide is an oxidative and reductive elimination agent that can be used in a variety of synthetic reactions. This compound can be used to synthesize hydroxamic acids, alkenylations, carboxylates, and other functionalized organic compounds. This compound is also useful for the preparation of aromatic carboxylic acid derivatives. The mechanism for this reaction is the hydroxamic acid formation through reductive elimination followed by the addition of an alcohol or amine. The reaction begins with the oxidative cleavage of an ester or amide bond to form a carbonyl group and a hydroxylamine moiety. The hydroxylamine then undergoes reductive elimination to yield a hydroxamic acid. This process is catalyzed by metal ions such as copper (Cu), zinc (Zn), and iron (Fe).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methylquinoline-2-carboxaldehyde is a formylating agent that is used in the synthesis of heterocycles. It has been shown to react with methanol and mediated by oxidative conditions to produce formaldehyde. This reagent can be used for the functionalization of biomolecules by reacting with amines, thiols, and hydroxyl groups. 4-Methylquinoline-2-carboxaldehyde can also be used for the oxidative coupling of phenols and naphthols. The functional group on this compound is a carboxylic acid (-COH).</p>

<p>8-Thia-4,6-diazatricyclo[7.5.0.0,2,7]tetradeca-1(9),2(7),5-trien-3-one is a synthetic antifungal molecule with inhibitory properties against the growth of fungi. This compound inhibits the biosynthesis of ergosterol, an essential component of the fungal cell membrane, by inhibiting the enzyme squalene epoxidase. 8-Thia-4,6-diazatricyclo[7.5.0.0,2,7]tetradeca-1(9),2(7),5-trien-3-one has been shown to be effective in killing Candida albicans and other species of pathogenic fungi in cell culture and animal models.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-5-one (6,7-DHP) is a muscarinic acetylcholine receptor agonist that has been shown to have profiles of both an agonist and antagonist. It was discovered by screening compounds against the acetylcholine receptor in the presence of different concentrations of acetylcholine. 6,7-DHP activates the receptor at low concentrations and inhibits it at higher concentrations. 6,7-DHP is used as an experimental tool to investigate the function of the muscarinic acetylcholine receptor in various diseases such as psychiatric disorders and inflammatory diseases. The molecule also has potential therapeutic applications for these disorders.</p>

<p>1H,2H,3H-pyrrolo[3,4-c]pyridin-3-one is a phosphoinositide synthesis inhibitor. It is an important drug target for the treatment of cancer due to its ability to inhibit the production of phosphoinositides that are necessary for the regulation of cell growth, proliferation and differentiation. The therapeutic potential of 1H,2H,3H-pyrrolo[3,4-c]pyridin-3-one has been demonstrated through chemistry studies and medicinal chemistry approaches. This molecule was synthesized with a 3-kinase inhibitor moiety and a reactive carboxamides group.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>2-(2,3-Dihydro-1H-indol-3-yl)ethan-1-ol is a crystalline compound that can be prepared by the addition of hydrogen chloride to 2-(2,3-dihydroindol-3-yl)ethanol. It is an enantiomer of 1-(2,3-dihydroindol-3-yl)ethanone. The compound has been used as a reagent in analytical chemistry and as a substrate for oxidases and other enzymes.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Diethyl (methylsulfonylmethyl)phosphonate is a synthetic compound that has been shown to inhibit the mineralocorticoid receptor. This receptor is involved in the regulation of electrolyte and fluid balance. The inhibition of this receptor by diethyl (methylsulfonylmethyl)phosphonate may be due to its ability to bind to the receptor's active site and prevent it from binding with other hormones, such as aldosterone. Diethyl (methylsulfonylmethyl)phosphonate also has antiviral and anti-cancer properties. It can inhibit the proteolytic activity of a virus, such as hepatitis, or protease enzymes found in cancer cells. Diethyl (methylsulfonylmethyl)phosphonate can also act as an allergen for some people and cause skin irritation.</p>

<p>2,2-Dimethyl-1,3-dioxan-5-amine is an organic molecule that utilizes electron affinity to synthesize with a variety of orientations. The hydrophobic and intramolecular orientations are the most common. The 2,2-dimethyl-1,3-dioxan-5-amine molecule has been shown to be capable of utilizing the hydrogen atom in water as an electron acceptor and donor. It can also form a monolayer on a gold electrode surface. This molecule is hydrophilic and therefore prefers hydrophilic environments such as the electrode surface or water. Impurities in this compound may include fluoride ion or chloride ion.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(4-Cyanophenyl)formamido]acetic acid is a secondary metabolite that is found in plants. It has been isolated from the leaves of the plant, Aerva lanata. 2-[(4-Cyanophenyl)formamido]acetic acid has been used as an analytical standard and as a reference material for quality control testing in the pharmaceutical industry. This compound is also being studied for its bioactive properties, including anti-inflammatory and antimicrobial activities.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>