Building Blocks

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Acetaminophen is a drug used to treat pain and fever. It belongs to the class of drugs called analgesics, which are also known as non-steroidal anti-inflammatory drugs (NSAIDs). Acetaminophen has been shown to be effective in the treatment of bowel disease and inflammatory bowel disease. Acetaminophen is usually given orally or intravenously, but it can also be given rectally for bowel disease. Acetaminophen is an analog of phenacetin, which was replaced in many countries because phenacetin was found to cause kidney damage. The mechanism by which acetaminophen relieves pain and reduces fever is not well understood. It may inhibit prostaglandin synthesis, block cyclooxygenase, or inhibit the production of substances that sensitize nerve endings to pain. Acetaminophen can cause allergic reactions such as skin rash, urticaria and angioedema. Acetaminophen also causes psychiatric side effects such as anxiety, mood</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Methylsulfonyl)aniline is a benzodioxole that inhibits tyrosine kinases. It has been shown to have potent inhibitory effects on the activity of receptor tyrosine kinases, which are involved in the transmission of signals from cell surface receptors to the interior of cells. 3-(Methylsulfonyl)aniline has been shown to be an inhibitor of various protein kinases including PDGF receptor, insulin receptor, and c-Kit. The crystal structure of 3-(methylsulfonyl)aniline bound to an ATP molecule has been determined by X-ray crystallography and shows interactions with residues in the ATP binding pocket.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylnonanoic acid is a fatty acid that is involved in the metabolism of energy. It is a long-acting contraceptive and has been shown to decrease body fat and weight gain in animals. 3-Methylnonanoic acid also inhibits the uptake of fatty acids into cells, which may be due to its ability to acetylate the cytosolic protein acyl CoA synthetase 2 (ACS2). The acetylation of ACS2 may alter its conformation, leading to an inefficient method for fatty acid uptake. 3-Methylnonanoic acid can be synthesized in a two-step process by cross-coupling of methyl esters with acetonitrile. This efficient synthesis provides a practical method for producing this compound on an industrial scale.</p>

<p>Indane-5-sulphonamide is a sulfonamide drug that has been shown to inhibit the growth of cancer cells in vitro and in vivo. It is an anti-diabetic agent that inhibits glucose uptake by inhibiting glycolysis. Indane-5-sulphonamide has also been shown to have inhibitory properties against aerobic glycolysis, which may be related to its acidic character. Indane-5-sulphonamide may be used as an adjuvant therapy for the treatment of cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Carbamothioylbenzoic acid is an antimicrobial agent that is used to treat chronic bacterial infections. It has been shown to inhibit the synthesis of proteins by binding to the ribosome, preventing peptide bond formation. 3-Carbamothioylbenzoic acid has been shown to be effective against a number of bacteria, including protocatechuic acid, benzoate and all-trans-retinoic acid. The reaction products are thought to be responsible for its antibacterial activity. 3-Carbamothioylbenzoic acid also inhibits the production of cycloheximide, an inhibitor of protein synthesis. This inhibition prevents cell division and leads to cell death by apoptosis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(3-Pentyl)pyridine is a colorless and odorless liquid that is soluble in organic solvents. It has been shown to be a good solvent for many organic compounds, such as the acetonitrile, and has a high boiling point. 4-(3-Pentyl)pyridine can also undergo photolysis and thermally induced reactions, which may make it suitable for use as an additive in solar cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-(2-Hydroxyethyl)-N-methyldodecanamide is a surfactant that is used in cosmetics for its ability to form micelles and solubilize fatty acids and oils. It is a hydrophobic molecule with a high viscosity, which makes it suitable for use in products such as shampoos, body lotions, and face creams. N-(2-Hydroxyethyl)-N-methyldodecanamide can also be used as an emulsifier in the preparation of foods such as mayonnaise, salad dressings, and whipped cream. This compound has been shown to be toxic to the worm Caenorhabditis elegans at concentrations above 10%.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>-2(5-Methylisoxazol-3-Yl)Acetonitrile is a heterocyclic compound that is used as a catalyst in cross-coupling reactions. It can be utilised for the synthesis of aromatic heterocycles and tosylate derivatives. -2(5-Methylisoxazol-3-Yl)Acetonitrile is an analogue of 2,5-dimethylisoxazole, and it can be used as a synthetic intermediate for the synthesis of various pharmaceuticals.</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Chloromethyl)-5-methylisoxazole is an organolithium reagent that is used for the synthesis of a variety of complex organic compounds. 3-(Chloromethyl)-5-methylisoxazole is a versatile reagent that can be used in metallation reactions, cycloadditions, and selective transformations. The selectivity of this reagent has been shown to be due to its ability to form stable organolithium compounds with heteroatoms such as oxygen and nitrogen.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Pentylamino)ethan-1-ol is a hydric compound that contains an ethanolamine group. It has antibacterial properties and reacts with polyvinyl chloride, which can produce reactive compounds. 2-(Pentylamino)ethan-1-ol is also used as a reactive ingredient in the synthesis of polyvinyl alcohols and polyvinyl acetates. The hydroxyl group on the molecule reacts with aromatic hydrocarbons, such as benzene, to form a cationic surfactant. This product is used in textile production to enhance dyeing and printing processes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Chlorpromazine is a potent antipsychotic drug that is used to treat mental disorders such as schizophrenia and bipolar disorder. It works by blocking the action of dopamine, a neurotransmitter in the brain. Chlorpromazine has minimal acute toxicity in animals and low potential for abuse or addiction. The most common side effects are drowsiness, dry mouth, nausea, and sedation. Chlorpromazine can interact with other drugs such as diazepam or chlorodiazepoxide to produce an anxiolytic effect. It also interacts with analgesics to produce depressant effects by increasing their sedative properties. In monkeys, chlorpromazine has been shown to have anxiolytic efficacy and depressant effects when given at high doses.</p>

<p>5,6,7,8-Tetrahydroquinoxalin-5-ol is a chiral compound that can be used to synthesize carboxylic acid derivatives. It is prepared by the catalytic hydrogenation of 5-(hydroxymethyl)tetrahydroquinoxaline-2,3(1H)-dione (1). The enantiomeric purity of this compound can be determined by its reaction with sulfuryl chloride in hydrochloric acid (HCl) to yield the corresponding sulfonyl chloride. This reaction forms an asymmetric sulfonamide that can then be separated by crystallization.</p>