Building Blocks

2-Hydroxy-N-phenylacetamide is a phosphoric acid that is an amide. It can be synthesized by reacting phenylacetic acid with 2-chloroethanol in the presence of sodium hydroxide and phosphoric acid. This chemical compound has electrocardiographic activity and is used as a synthon to create other drugs, such as inorganic acids, supramolecular complexes, and intermolecular hydrogen bonding compounds. 2-Hydroxy-N-phenylacetamide has been shown to lower blood pressure in clinical studies. It also prevents the formation of methemoglobin caused by exposure to nitrites or nitrates and has been shown to be effective against carboxylate ions such as potassium ion (K+).

<p>Versatile small molecule scaffold</p>

1-Phenyl-1H-pyrazole-3-carboxylic acid is an organic compound that has a pyrazole ring. It can be synthesized by the reaction of phenylhydrazine and formamide. The amido group in the molecule is bound to the carbonyl carbon atom, which makes it a carboxylic acid. This compound is also known as a morpholine amido ester. One example of this type of compound is 1-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid. The analogous compound in this series is 2-(2,6-dimethylphenyl)-1H-pyrrole-3-carboxylic acid.

2-(1H-Indol-2-yl)phenol is a functional group that exhibits optical properties. It has a carbinol group and an acidic proton. In the excited state, it can transfer a proton to nucleophilic molecules and react with other compounds. 2-(1H-Indol-2-yl)phenol is also an important reaction product of indole synthesis. This compound has been shown to exhibit fluorescence and is a member of the phenols family.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Methyl-5-nitro-1H-imidazole-2-carbaldehyde (MNNCA) is a synthetic fatty acid that has been shown to have genotoxic potential. It is also used as a clinical drug and as a test compound. MNNCA has been found to inhibit the activity of the antioxidant system, which may lead to an increased risk of nitrosative stress and DNA damage. In vitro assays have demonstrated that MNNCA can cause genotoxic effects in cultured cells. Studies using diminazene, a crosslinking agent, have shown that MNNCA can be metabolized by cytochrome P450 enzymes and this metabolism may lead to pharmacokinetic properties such as protein binding or changes in protein expression.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Valproic acid is an organic compound with the formula (CHCO)COOH. It is a white crystalline solid that is insoluble in water and most organic solvents. Valproic acid has been used in medicine as an anticonvulsant, mood stabilizer, and bipolar disorder medication. Valproic acid is also used to treat hyperammonemia, although this use is limited by its side effects. To produce valproate semisodium, sodium carbonate and valproic acid are combined at high temperatures to form sodium valproate and carbon dioxide gas. The molecular weight of valproic acid ranges from 100-400 Da. The low molecular weight of this drug makes it suitable for oral absorption and rapid distribution throughout the body. This assay uses a chromatographic method for detection with fluorescence detection at excitation/emission wavelengths of 280/365 nm. The results show that 6-Amino-2-propylhexano</p>

<p>o-Tolylbiguanide hydrochloride is a copper-containing antimicrobial agent that has been synthesised and used to treat Gram-negative bacteria. It is an anion, which means it can be reduced by agents such as formaldehyde and chloride. o-Tolylbiguanide hydrochloride binds to the anionic groups of the bacterial cell wall, which are found in proteins and lipids. This binding prevents the formation of a covalent bond between the copper ion and the bacterial cell wall, preventing further growth. The elimination of this compound in vivo is thought to be due to its organic ligands.</p>

<p>3-(1-Hydroxyethyl)pyridine is a levorotatory, white solid. It is used in animal studies to study the effects on the brain and other body systems. 3-(1-Hydroxyethyl)pyridine is synthesized by a three-step process that involves converting 3-acetylpyridine into 3-(2-hydroxyethyl)pyridine, which is then converted to 3-(1-hydroxyethyl)pyridine. This compound has been shown to be an adrenergic receptor agonist and may have some potential as a drug for treating Parkinson's disease. It also has acidic properties and substructures that are enantiopure, meaning they are composed of molecules with the same chirality.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>1,4,6-Triamino-1,2-dihydropyrimidine-2-thione is a chemical compound that is soluble in water and methanol. It has been shown to cleave bonds by the use of sodium hydroxide solution.</p>

<p>Ethyl alpha-chlorophenylacetate (ECA) is a synthetic molecule that has been shown to have anti-inflammatory and neurodegenerative properties. It is a benzimidazole derivative with a hydroxyl group on the ethyl alpha-chlorophenylacetate moiety. ECA has been shown to inhibit inflammatory responses in mice by targeting transcription factors, such as NF-κB and AP-1, which are involved in the regulation of immune responses. It also has an anti-inflammatory effect on malonic acid induced colitis in mice.</p>

<p>1-Chloro-1-phenylpropan-2-one is an exploratory compound that has been deployed as a mechanistic probe to probe the radical mechanism of aldehydes. It has been shown that 1-chloro-1-phenylpropan-2-one can be used to generate fluorescent compounds and study the fluorescence, UV radiation, and radical mechanism of aldehydes. This molecule also has the ability to react with electron rich compounds such as aziridines to form chiral products. The substituent on this molecule will affect its biological activity.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>4-Methylphthalazin-1-amine is a heteroaromatic compound that can be synthesized by cyclization of phenacyl bromides and bromoacetates. It has been found in Australian plants and may have a role in the development of schizophrenia. 4-Methylphthalazin-1-amine is not soluble in water, but it can be dissolved in solvents such as acetone or ethanol. It is also insoluble in most organic solvents.</p>

<p>Versatile small molecule scaffold</p>

<p>1-Ethyl-1H-pyrrole-2-carboxylic acid is a chemical compound that is used as an organic solvent. It is also known as ethyl formate, which is a colorless liquid with a sweet odor. This ester is used to produce esters and other compounds for use in the synthesis of polymers or dyes. It can be halogenated and may be used as an acid ester or acid anhydride. 1-Ethyl-1H-pyrrole-2-carboxylic acid has shown to have some antiinflammatory properties, but it can also cause severe eye irritation and skin sensitization.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>4-Aminopyrimidine-5-carboxamide is an amide that is synthesized from the reaction of eosinophil and amine. This compound inhibits transcription in a dose-dependent manner, with a high potency for iminium and amines, but not primary amines. 4-Aminopyrimidine-5-carboxamide is orally bioavailable and has shown to be effective in animal models. The compound has been optimized for oral administration and has shown to produce good yields. 4-Aminopyrimidine-5-carboxamide also possesses transcription factor inhibitory activity against interleukin, which may provide therapeutic benefit for inflammatory disorders.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

2-Chloro-acetyl)-urea is a disinfectant that has been shown to be active against bacterial spores. It reacts with sodium taurocholate to form mercuric chloride and triazine, which are the reaction products of the 2-chloro-acetyl)-urea. The molecular modeling study of 2-chloro-acetyl)-urea showed that this molecule has a hydrophobic region and can bind with water molecules through hydrogen bonding. This property allows it to act as a detergent composition in cleaning products. 2-Chloro-acetyl)-urea also has an ethyl diazoacetate group, which is used in biocides for its ability to penetrate cell membranes. 2-Chloro-acetyl)-urea is also used in molecular modeling studies as a substrate for s-adenosylhomocysteine hydrolase (SAHH) enzymes, which are involved in the synthesis of ad

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>4-Benzyloxybutan-2-ol is an immobilization linker that is used to connect a molecule to a solid surface, such as glass. The carboxylate group of 4-benzyloxybutan-2-ol reacts with the hydroxyl groups on the glass surface and forms a covalent bond by reacting with the amine groups of the molecule. This linker can be used for immobilizing biomolecules or synthetic molecules in order to study their kinetics or other properties. It is also used for solid phase synthesis. 4-Benzyloxybutan-2-ol has been shown to be biocatalyzed by lipase and has been shown to have high reactivity at temperatures below 40°C. Techniques such as IR spectroscopy, NMR spectroscopy, and mass spectrometry are commonly used to characterize this compound.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold