Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Chloro-3,3-dimethylpentane is a liquid phase selective dehydrochlorination catalyst that selectively removes chlorine from chlorinated hydrocarbons. The reaction product of 1-Chloro-3,3-dimethylpentane is a stable substance with high yield and catalytic activity. The catalyst has shown to be deactivated by impurities such as sulfur or phosphorus compounds.</p>

<p>4-Methylcyclohexanemethanol (4MCHM) is a glycol ether that has been found to be an active compound for the treatment of tuberculosis. It is activated by light, which causes it to emit light and break down into formaldehyde. In vitro assays have shown that 4MCHM inhibits bacterial growth and enzyme activities. The hydrogenated form of 4MCHM has a similar effect in vitro but does not break down into formaldehyde, meaning it can be used as a safer alternative for the treatment of tuberculosis. 4-Methylcyclohexanemethanol has also been shown to have significant interactions with the enzymes CYP2E1, CYP3A4, CYP2C9, and CYP2D6 in vitro and in vivo. The toxicological profile of 4-methylcyclohexanemethanol has been investigated using in vitro assays on bacterial strains and solid phase microextraction experiments on cell</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methoxy-6-methylsalicylaldehyde is a synthetic aldehyde that has been used in the production of propionyl. It is an intermediate for formylation, hydroxylation and peroxidation reactions. The high-performance liquid chromatography technique was used to separate 4-methoxy-6-methylsalicylaldehyde from other aldehydes. The compound can be protonated by strong acids and can undergo silicone polymerization reactions. 4-Methoxy-6-methylsalicylaldehyde is also soluble in ethers, alcohols and esters. This class of compounds are usually found in lettuce leaves and have the characteristic phenolic odor.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Cyclopentylpyridin-4-amine is a chemical compound with the formula CH(NH)CHCClN. It is an alkylation agent that consists of a cyclopentanol group and a pyridine ring. The cyclopentanol group reacts with electrophiles such as 2-propanol and 4-aminopyridine to form a cyclohexanol derivative. This reaction is catalyzed by sulfuric acid. N-Cyclopentylpyridin-4-amine has been used for the preparation of cyclopentanols, which are valuable intermediates in organic synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-formylphenyl)acetic acid is a synthetic chemical compound with anticancer properties. It has been shown to inhibit proliferation of human cancer cells in vitro and in vivo. The mechanism of action is not yet known, but it has been hypothesized that 2-(4-formylphenyl)acetic acid may act as a copper complex or by binding to amide groups on the surface of cancer cells. This study also showed that this compound can activate toll-like receptor 4 (TLR4). 2-(4-formylphenyl)acetic acid has also been shown to inhibit the uptake of biphosphates by cells, which may be due to its methoxy groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(4-Methylpyridin-2-yl)piperazine (1MPP) is a potent 5-lipoxygenase inhibitor that inhibits the synthesis of leukotrienes and histamine. 1MPP is an effective antiasthmatic drug and has been shown to have potent activities against asthma, bronchial asthma, chronic obstructive pulmonary disease, and allergic rhinitis. The pharmacological effects of 1MPP are due to its ability to inhibit the biosynthesis of leukotrienes from arachidonic acid by blocking the enzyme 5-lipoxygenase. This inhibition leads to a decrease in inflammatory reactions caused by these molecules.</p>

<p>1-Naphthaleneacethydrazide is a hydrazone compound that can be synthesized by reacting 1-naphthol with ethylhydrazine. It has been shown to be a very powerful and selective oxidant, with a high conversion yield. The compound is used in the synthesis of transition metal complexes, including octahedral, square planar and tetrahedral complexes. Transition metals such as chromium, nickel and iron are used in the catalytic production of polymers. Hydrazides can be used as reducing agents or as precursors for other compounds. The hydrazones are also used in the preparation of magnetic materials.<br>1-Naphthaleneacethydrazide has been shown to have a strong affinity for elemental nitrogen and has been proposed as an oxidizing agent for nitrogen gas (N2) reduction.</p>

<p>1-Benzyl-1,3-diazinan-2-one is a fluorobenzene that contains an aromatic ring with a nitrogen atom in the 1 and 2 positions. This compound is an ionization mass spectrometric standard for the molecular ion at m/z = 123. The electron ionization spectrum of this compound exhibits a single peak at m/z = 123, which corresponds to the molecular ion. The fragmentation of 1-benzyl-1,3-diazinan-2-one yields two peaks at m/z = 67 and 69. These fragments correspond to the loss of one hydrogen from C6 and C8 respectively.</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(Methylsulfanyl)methyl]aniline is a substituted aniline that has the chemical formula C6H8NS. It is a colorless to white solid that is soluble in polar solvents such as water, alcohols and ethers. 2-[(Methylsulfanyl)methyl]aniline has a molecular weight of 194.2 g/mol and chemical formula C6H8NS. The molecule can be classified as a secondary amine with two methyl sulfanyl substituents on the benzene ring. The compound has a melting point of 110°C and boiling point of 220°C at atmospheric pressure. The infrared spectrum for the compound displays absorptions at 3,900 cm-1 (O-H), 1,650 cm-1 (N-H), 1,200 cm-1 (C=O) and 730 cm-1 (C=N). The magnetic resonance spectrum displays signals at δ =</p>

<p>Versatile small molecule scaffold</p>

<p>1-(5-Bromothiophen-2-yl)-2,2,2-trifluoroethanone is a fluorescent probe that binds to proteins in the brain. This probe has been shown to have high affinity for human brain and selectively targets neurodegenerative diseases such as Alzheimer's disease. It is also a selective probe for molecular imaging of the brain and has been shown to be permeable to cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Bromophenoxy)ethanol is a primary alcohol that can be used as a probe in enzymatic reactions, such as the ring-opening of pyridinium salts. It reacts with nucleophilic compounds to form lactams, which are macrocyclic molecules. 2-(2-Bromophenoxy)ethanol can also be used to synthesize epoxides and alcohols.</p>

<p>Ethylene Glycol Mono(4-bromophenyl) Ether is an organic compound with the chemical formula C6H5BrOCH2. It is a colorless liquid, which can be obtained by reacting benzophenone with magnesium in diethyl ether. It is used to synthesize organolithiums and organomercurials. Ethylene Glycol Mono(4-bromophenyl) Ether can be prepared by reacting naphthalene with mercuric chloride. The product is obtained as a white solid or crystalline powder after crystallization from ethanol.</p>

<p>1-Ethyl-1H-benzoimidazole-2-carbaldehyde is a nonspecific heteroaromatic compound that has been shown to be sensitive to solvation. The conformers of this molecule have been determined by intramolecular sensitivity and regression analysis. This molecule is an intramolecular heteroaromatic compound with an electronic transition. The conformers are determined by the polarizability and electronic transitions of the molecule. This molecule has solvatochromism, which is a change in color due to changes in solvent polarity. 1-Ethyl-1H-benzoimidazole-2-carbaldehyde has been shown to exhibit conformational changes in response to changes in temperature, pressure, or solvent conditions, which can lead to changes in its physical properties such as color and melting point.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Pentamethylphenylacetonitrile (PMP) is an aldehyde that is used as a reagent in the synthesis of other chemical compounds. It is also used in the preparation of phase transfer catalysts. PMP is typically available as a white powder and can be dissolved in organic solvents such as acetone or benzene. The chemical properties of PMP are similar to those of other aldehydes, including its susceptibility to oxidation, which can lead to the formation of carboxylic acids.</p>

<p>Methyl 4-nitro-3-phenylbutanoate is a nitro compound that is used as a reagent for the silylation of phenols. It is also used in the synthesis of functionalized aliphatic nitro compounds and has been found to be able to eliminate certain nitrosamines. Methyl 4-nitro-3-phenylbutanoate is an aliphatic, nitro compound with conjugated stereochemistry.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6,7,8,9-Tetrahydro-5H-benzo[7]annulen-6-one is an underserved drug candidate for tuberculosis. 6,7,8,9-Tetrahydro-5H-benzo[7]annulen-6-one has been shown to be a potent inhibitor of bacterial lactamase enzymes that are involved in the resistance of bacteria to many antibiotics. 6,7,8,9-Tetrahydro-5H-benzo[7]annulen-6-one is also able to bind to the electron withdrawing group on the lactam ring and stabilize the molecule. This binding prevents conformational changes in the lactamase enzyme and inhibits its activity. 6,7,8,9 tetrahydro 5H benzo[7]annulen 6 one has been shown to have potential use in treating tuberculosis due to its activity against drug resistant bacteria</p>