Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Pyridin-4-yl-imidazolidin-2-one is a potent inhibitor of the growth hormone receptor, which in turn prevents the activation of the insulin receptor and glycogenolysis. It has been shown to attenuate cachexia in mice by reducing their weight loss. 1Pyridin-4-yl-imidazolidin-2-one also exerts an antihypertensive effect on congestive heart failure by inhibiting alpha 2 adrenergic receptors. This drug has been shown to have a stimulatory effect on premarin production and to be an effective insecticide against aphids, mites, and caterpillars.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Acetamido-4-picoline (3AP) is a fatty acid that has been used in the treatment of autoimmune diseases. It is also a potent activator of AMPK, which is an enzyme that regulates cellular metabolism and energy homeostasis. 3AP has been shown to have antibacterial activity against a wide range of bacteria, including Mycoplasma and endophytic fungi. 3AP also inhibits leukotriene receptor antagonists, which are important for the inflammatory response. 3AP may be used as a diagnostic agent to measure body fat mass and body mass index in humans. The type strain for this compound is ATCC 21797.

Versatile small molecule scaffold

Versatile small molecule scaffold

4-(Benzyloxy)-2-hydroxybenzaldehyde is a functional compound that has various tautomeric forms. It can be found in the mesomorphic form at low temperatures and in the imine form at higher temperatures. It is also active as an anti-inflammatory agent, inhibiting cyclooxygenase and lipoxygenase enzymes. 4-(Benzyloxy)-2-hydroxybenzaldehyde has been shown to have a protective effect on cells from Alzheimer's disease and other neurodegenerative diseases by preventing the aggregation of beta-amyloid proteins that are implicated in these diseases.

Versatile small molecule scaffold

Versatile small molecule scaffold

Dicyclohexylacetic acid is an organic compound that is used as a reagent to measure the binding constants of proteins. It has a hydrophobic effect, which may be due to its particle size, and it has been shown to have antioxidant properties. Dicyclohexylacetic acid is also used in the production of chemical structures, such as hydrogen bond and carboxylate. It can be used in the treatment of autoimmune diseases by inhibiting serine protease activity and radiation therapy. Naphthenic acids are found in crude oil, and FT-IR spectroscopy can be used to detect these acids.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

(Iodomethyl)cyclopentane is a potent cytotoxic agent that inhibits the proliferation of a wide range of cells. It binds to the DNA of proliferating cells and causes cross-linking and strand breakage, which leads to cell death. This compound also has anti-inflammatory properties and can be used in hyperproliferative diseases such as cancer, as well as infectious diseases such as tuberculosis. (Iodomethyl)cyclopentane is not available for sale in its pure form, but rather in a salt form.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2,4,6-Trichlorobenzenesulfonyl chloride is a sulfonylating agent that is used to treat metabolic disorders and iron metabolism. It is also used as an x-ray contrast agent for the detection of certain types of cancers. In addition, 2,4,6-trichlorobenzenesulfonyl chloride has been shown to have anti-inflammatory properties in chronic inflammatory diseases. This drug can be used to inhibit the synthesis of hepcidin by blocking the catalytic activity of ferrochelatase. 2,4,6-trichlorobenzenesulfonyl chloride may also be able to reduce inflammation by its ability to form reactive chlorides that react with alcohols and aldehydes. This can lead to deficiency symptoms such as chronic inflammatory disease or alcohol intolerance.

5-(4-Hydroxyphenyl) tetrazole is a hydrophobic ligand that has been shown to bind to cisplatin and therefore may have potential use in cancer therapy. It has also been used as an anti-inflammatory agent with the potential to inhibit prostaglandin synthesis. 5-(4-Hydroxyphenyl) tetrazole binds to hydrogen peroxide, which is a strong oxidizing agent and produces reactive oxygen species (ROS). ROS can cause DNA damage and lead to cell death by apoptosis or necrosis. 5-(4-Hydroxyphenyl) tetrazole reacts with cisplatin, which is a chemotherapeutic agent that is used in the treatment of various types of cancer. Cisplatin binds to DNA and prevents replication, leading to cell death. Hydrophobic ligands such as 5-(4-Hydroxyphenyl) tetrazole are able to bind more tightly than other ligands because

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Chlorophenylacetyl Chloride is a chlorinating agent that reacts with alkaline conditions to form a chloride. As an active ingredient in pesticides, it has been shown to have high selectivity and to be selective against fungi. The 2-chlorophenylacetyl chloride can be used as the starting material for epoxiconazole synthesis by Wittig reaction.
2-Chlorophenylacetyl Chloride is also a useful intermediate for the preparation of many other compounds. It can be used to synthesize dimethylchloride, which is used in the production of plastics and polymers; or it can be used to prepare formamide, which is used in the production of pharmaceuticals and agrochemicals. This compound has been shown to have catalysis properties and can be used in Wittig reactions that are selective towards different carbonyl groups.

Versatile small molecule scaffold