Building Blocks

Versatile small molecule scaffold

3-bromo-2-iodothiophene is a brominated heterocycle that can be used as an introducing group in organic synthesis. It has been shown to interact with fluorine and exhibit high affinity for this element. 3-bromo-2-iodothiophene also has the ability to cross-couple with other functional groups, such as cyclic or unsymmetrical ones. The compound is also capable of forming isoelectronic species, which are compounds with the same electron configuration. 3-bromo-2-iodothiophene can be used in semiconductors and other devices.

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Phenylhex-5-en-3-ol is a synthetic compound that has been used in the allylation of halides and as a chiral, enantiomerically pure building block for organic synthesis. The addition of 1-phenylhex-5-en-3 to an aldehyde followed by hydrolysis produces the corresponding ester. This reagent can also be used catalytically as an asymmetric hydrogenation catalyst, with selectivity depending on the solvent. It is an organic chemical that can be converted into other useful products such as solvents and pharmaceuticals.

Versatile small molecule scaffold

2,3,6-Trimethoxybenzoic Acid is an organic compound that is the product of the reaction of 3-hydroxyanthranilic acid with benzoic acid. It has been shown to be an antibacterial agent in vitro and has antitumour properties. 2,3,6-Trimethoxybenzoic Acid is a precursor for the synthesis of chorismate, which is an important biosynthetic intermediate for many antibiotics. The elucidation of its structure and mechanism of action may help scientists to better understand the microflora responsible for human diseases.

Versatile small molecule scaffold

Versatile small molecule scaffold

(6-Methoxynaphthalen-2-yl)methanol is a fluorescent probe that reacts with cytosolic proteins. When (6-methoxynaphthalen-2-yl)methanol is incubated with human liver, the rate of reaction increases in proportion to the concentration of cytosolic proteins. This probe can be used to detect changes in the activity of dehydrogenase and aldehyde oxidase enzymes, which are responsible for the metabolism of alcohols and aldehydes. The fluorescence intensity also increases when (6-methoxynaphthalen-2-yl)methanol binds to proteins due to an increase in its chromophore.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N-Boc-3-methoxyaniline is a chemical compound that belongs to the class of nitroreductase inhibitors. It has been shown to inhibit tumour growth by targeting the tumor microenvironment and inhibiting the production of reactive oxygen species. N-Boc-3-methoxyaniline also has anti-angiogenic properties, which may be due to its ability to suppress the production of nitric oxide. This agent can be used for monitoring and controlling cancer stem cells in vitro and in vivo. The fluorescent probes are suitable for imaging, measuring, and quantifying this type of cell.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold