Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Hydroxyethyl 2-hydroxypropanoate is a polyester that is produced by the dehydration of ethylene glycol and 2-hydroxyethanol. It is a biodegradable, degradable, and regenerative material that can be used in biomedical applications such as scaffolds for tissue engineering. The hydroxy group on the molecule has been shown to prevent protein adhesion and degradation. This product has been shown to inhibit growth of bacteria such as Staphylococcus aureus and Escherichia coli, which may be due to its ability to block the activity of cellular enzymes.

2-(Benzoylamino)-2-phenylacetic acid is a hydrazone that has been used as a precursor for the synthesis of azoalkenes. It is also biologically active and may be useful for the treatment of cancer.

2-(4-Chlorophenyl)butanoic acid is a metabolite of the drug baclofen. It is produced by Streptomyces, and has been found in cultures, experiments, and soil samples. This compound has been shown to metabolize through microbial metabolism with a chiral center (2R), which can be used as an indicator of microbial activity. 2-(4-Chlorophenyl)butanoic acid also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis.

Versatile small molecule scaffold

Heptyl carbamate is a cholinergic antagonist of the blood disorders. It has been shown to inhibit hydroxy and hiv infection. In vitro assays have shown that heptyl carbamate inhibits the synthesis of fatty acid, thereby reducing cholesterol levels and inhibiting the production of insulin resistance in cells. Heptyl carbamate also binds to the same site on acetylcholinesterase as donepezil, which blocks the breakdown of acetylcholine and leads to an accumulation of this neurotransmitter in nerve cells. This increased concentration of acetylcholine in nerve cells can lead to a reduced incidence of Alzheimer's disease-related symptoms.

5-Chloro-2,2-dimethylpentanenitrile is a nonpolar solvent that can be used as a phase transfer catalyst and reagent for the synthesis of cyclopentanone derivatives. It is also used as a hydrolyzing agent for the synthesis of 1-bromo-3-chloropropane. 5-Chloro-2,2-dimethylpentanenitrile can be used to synthesize cyclic ketones from alkyl halides and 1,1'-oxydiacetonitrile with an acetone or isobutyronitrile as a catalyst.

Pent-1-yn-3-ol is a low molecular weight compound that is classified as an amide. It is an intermediate in the biosynthesis of fatty acids and primary alcohols from acetyl-CoA. Pent-1-yn-3-ol also alkylates amides in proteins, and can be used for the synthesis of magnetic nanoparticles. In order to determine the effects of mononuclear alkali metal ions on organisms, methyl ethyl was added to a mixture of 10 mM potassium hydroxide (KOH) and water. The pH was then adjusted to 4 with hydrochloric acid (HCl). A magnetic stir bar was placed in the flask, and the solution was mixed magnetically at room temperature. The growth rate of Drosophila melanogaster was monitored over time by measuring its wet weight.

Versatile small molecule scaffold

4-Phenyloxane-2,6-dione is a molecule that has two asymmetric carbons. The molecule has been shown to undergo desymmetrization by the Friedel-Crafts acylation and protonation reactions. 4-Phenyloxane-2,6-dione has been used as a chiral catalyst to synthesize an α,β-unsaturated ketone with an unsymmetrical double bond.
4-Phenyloxane-2,6-dione can be used for asymmetric synthesis of aldehydes due to its bifunctional nature. This compound is also used in the catalysis of cyclic reactions.

Versatile small molecule scaffold

1-Chloro-4-methylpentan-2-one is a chemical compound that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to inhibit methicillin resistance in Staphylococcus aureus, and also has an antibacterial effect on other gram-negative bacteria. 1-Chloro-4-methylpentan-2-one is active against both gram positive and gram negative organisms, but the spectrum of activity is limited because it is not active against acid fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. 1CMTD has been shown to be stable in its crystalline form and can be administered orally.

4-(1H-1,3-Benzodiazol-2-yl)benzonitrile is a planar molecule with a dihedral angle of about 120°. The molecule consists of benzene rings and chains. The benzene ring is symmetrical, hence it has no plane of symmetry. As the molecule does not have any chiral centers, there are two enantiomers (mirror images).

2-(Propan-2-yl)thiophene is a cyclopropylamine that reacts with ruthenium to form a ruthenium complex. This complex is thermodynamically stable, and can absorb light in the visible region of the spectrum. The addition of ligands such as phenanthroline or isopropyl groups enhances its photophysical properties, and can be used to catalyze alkylation reactions. 2-(Propan-2-yl)thiophene has an electron-withdrawing group on the phenyl ring, which makes it susceptible to nucleophilic attack by electrophiles. This property is useful for kinetic studies of alkylation reactions, because it allows for observation of the rate at which an alkylating agent approaches a given substrate.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold