Building Blocks

Versatile small molecule scaffold

3-(Diethylamino)pyrrolidine is a pyrrolidine derivative that acts as a 5-HT1B receptor agonist. It has been shown to have both antidepressive and antiaggressive effects, although it does not appear to be an effective antidepressant. 3-(Diethylamino)pyrrolidine is also used in the treatment of gastrointestinal disorders, such as irritable bowel syndrome, and has been shown to be effective in treating lymphoblastic leukaemia. This drug has been found to act as a 5-HT1B receptor agonist and is structurally related to other drugs that are used in the treatment of psychiatric disorders. It has also been found to have both antidepressive and antiaggressive effects, although it does not appear to be an effective antidepressant. 3-(Diethylamino)pyrrolidine is an amide derivative with a c1-c4 alkyl chain and has formulae

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Applications 1,3,5-Trifluorotrichlorobenzene is a useful reagent.

Applications 4-Diazobenzenesulfonic acid (cas# 305-80-6) is a useful research chemical.

Timonacic is an analog of nicotinamide that has been shown to be an effective inhibitor of energy metabolism in the mitochondria. It has antioxidative properties and can protect against the development of heart disease by inhibiting the production of reactive oxygen species. Timonacic's anti-inflammatory properties may be due to its ability to inhibit prostaglandin synthesis. It also has a high affinity for fatty acids, which may contribute to its inhibitory effects on lipid peroxidation. This drug has a carboxy terminal and is used as a sodium salt, which may play a role in its enzyme inhibition activity. Timonacic inhibits the activities of enzymes such as carnitine acetyltransferase and pyruvate dehydrogenase kinase, which are involved in the biosynthesis of fatty acids. The intramolecular hydrogen bonds formed with timonacic may contribute to its inhibitory effect on these enzymes.

Versatile small molecule scaffold

Versatile small molecule scaffold

Trans-3-(Benzyloxy)cyclobutanol is a radiolabeled compound that is used as a model system for understanding the metabolism of drugs in humans. It has been shown to be metabolized by the liver to produce metabolites that are excreted in urine. Trans-3-(Benzyloxy)cyclobutanol has also been shown to have tumor cell line stability, which may be due to its ability to inhibit DNA synthesis and protein synthesis in vitro and reduce tumor cells in vivo. Trans-3-(Benzyloxy)cyclobutanol has been shown to have no effect on normal rat plasma and lung carcinoma cells, but does affect prosthetic group activity.

2-Chloro-3-(hydroxymethyl)pyridine is an organic compound that is used as a building block for the synthesis of other heterocycles. This compound can be synthesized from 2-chloronicotinic acid, which is obtained by oxidation of nicotine with sodium hypochlorite in the presence of potassium ion. The reaction proceeds via a cleavage of the C-Cl bond and formation of a pyridine ring. The catalytic process can be performed at room temperature and at atmospheric pressure in a variety of solvents, including water.
2-Chloro-3-(hydroxymethyl)pyridine has been shown to have high yields for the preparation of compounds such as 2,4-dichloropyridine and 4,5-dichloropyrimidine. It also has been used in the preparation of pharmaceuticals such as atrial natriuretic factor (ANF).