Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N-2-Pyrimidinyl-glycine is a natural amino acid that is present in many protein mixtures. N-2-Pyrimidinyl-glycine has been shown to have affinity for the lipid bilayer of membranes, which may be due to its ability to act as a carbamate. The transport of this amino acid across membranes has been studied computationally and experimentally. Experimental results show that N-2-pyrimidinylglycine can be used as an absorbent for liquids such as oil or water. The molecule has also been shown to have spectroscopic properties, which make it useful in studies related to natural amino acids.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Tetrahydroquinolin-2(1H)-one is a hydrobromide that has been found in the environment as an environmental pollutant. Tetrahydroquinolin-2(1H)-one is used to synthesize amides and has been studied by single-crystal x-ray diffraction. The molecule is centrosymmetric, with a molecular weight of 244.06 g/mol. Tetrahydroquinolin-2(1H)-one can be used as a ligand for metals such as chlorine and magnesium. It does not dissolve in water but does dissolve in organic solvents such as ethers, chloroform, or benzene.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(Phenylamino)acetohydrazide is a non-steroidal antibacterial agent that binds to the active site of bacterial ribosomes and inhibits protein synthesis. The molecule is stabilized by electron-withdrawing groups, which are favorable for binding to metal ions. 2-(Phenylamino)acetohydrazide has been shown to be effective against a wide range of bacteria, including E. coli, Pseudomonas aeruginosa, Candida neoformans, and Staphylococcus epidermidis. It also has a strong inhibitory effect on S. epidermidis and Escherichia coli.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Hydroxy-3,3-dimethylbutanoic acid is an organic compound that is used as a precursor to hypochlorite. It is synthesized by the catalytic oxidation of ethyl formate with a palladium catalyst in an alkaline solution. The resulting 2-hydroxy-3,3-dimethylbutanoic acid has a high yield and can be used as a starting material for the manufacture of sodium hypochlorite and other chlorinating agents. The optical purity of the product can be improved by using ruthenium or copper catalysts in place of palladium.

1-Pyridin-4-yl-imidazolidin-2-one is a potent inhibitor of the growth hormone receptor, which in turn prevents the activation of the insulin receptor and glycogenolysis. It has been shown to attenuate cachexia in mice by reducing their weight loss. 1Pyridin-4-yl-imidazolidin-2-one also exerts an antihypertensive effect on congestive heart failure by inhibiting alpha 2 adrenergic receptors. This drug has been shown to have a stimulatory effect on premarin production and to be an effective insecticide against aphids, mites, and caterpillars.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Acetamido-4-picoline (3AP) is a fatty acid that has been used in the treatment of autoimmune diseases. It is also a potent activator of AMPK, which is an enzyme that regulates cellular metabolism and energy homeostasis. 3AP has been shown to have antibacterial activity against a wide range of bacteria, including Mycoplasma and endophytic fungi. 3AP also inhibits leukotriene receptor antagonists, which are important for the inflammatory response. 3AP may be used as a diagnostic agent to measure body fat mass and body mass index in humans. The type strain for this compound is ATCC 21797.

Versatile small molecule scaffold

4-(Benzyloxy)-2-hydroxybenzaldehyde is a functional compound that has various tautomeric forms. It can be found in the mesomorphic form at low temperatures and in the imine form at higher temperatures. It is also active as an anti-inflammatory agent, inhibiting cyclooxygenase and lipoxygenase enzymes. 4-(Benzyloxy)-2-hydroxybenzaldehyde has been shown to have a protective effect on cells from Alzheimer's disease and other neurodegenerative diseases by preventing the aggregation of beta-amyloid proteins that are implicated in these diseases.

Versatile small molecule scaffold

Versatile small molecule scaffold

(Iodomethyl)cyclopentane is a potent cytotoxic agent that inhibits the proliferation of a wide range of cells. It binds to the DNA of proliferating cells and causes cross-linking and strand breakage, which leads to cell death. This compound also has anti-inflammatory properties and can be used in hyperproliferative diseases such as cancer, as well as infectious diseases such as tuberculosis. (Iodomethyl)cyclopentane is not available for sale in its pure form, but rather in a salt form.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Isophthalic Dihydrazide is an ethylene diamine that reacts with oxadiazole and trifluoroacetic acid to form a polymeric coating on the surface of nickel particle. It is used in the production of epoxy resins for automotive coatings and as a hardener for paints and varnishes. Isophthalic Dihydrazide reacts with hydroxyl groups on the surface of polymer particles to produce cross-linking, which increases the resistance of the polymer against water vapor and other substances. The optimum concentration for this product is between 0.1% - 0.5%.