Building Blocks

2-(2,6-Dimethylphenyl)ethan-1-ol is a racemic mixture of two compounds with the same molecular formula. The two enantiomers have different chemical properties and can be separated by specific techniques such as chromatography. 2-(2,6-Dimethylphenyl)ethan-1-ol is an ether that is made from methylmalonic acid and ethylene oxide. It is hydrolysed to release methylmalonyl chloride or demethylated to produce methyl ether acetate. This compound has been used in the synthesis of various esters and sesquiterpenoids.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-[(3,5-Dimethylphenyl)formamido]acetic acid is a compound with diverse applications and characteristics. It is a diphenyl ether that can be used as an electrode material in various electronic devices. Additionally, it has cholinergic properties, meaning it affects the neurotransmitter acetylcholine in the nervous system.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Cyclohexylpropane-1,3-diol is a substrate for porcine pancreatic lipase. It is hydrolyzed by this enzyme, which is stereoselective and enantioselective. 2-Cyclohexylpropane-1,3-diol also has properties that are similar to angiotensin, a peptide that is secreted by the human body. This substance can be used as a solvent for other organic compounds in chemical reactions.

Versatile small molecule scaffold

Acetic acid, dibromo-, ethyl ester is a reactive molecule that can be used as a nucleophilic substituent. It has hydroxyl group and ruthenium complex. It is a particle that can be used in the production of monoclonal antibodies. Acetic acid, dibromo-, ethyl ester also has viscosity and polycarboxylic acid. This chemical reacts with β-unsaturated ketones to form polymerization initiator. Acetic acid, dibromo-, ethyl ester also has carbonyl group and monoclonal antibodies. Acetic acid, dibromo-, ethyl ester can be conjugated with ethyl bromoacetate to produce conjugates.

2-[(3-Nitrophenyl)formamido]acetic acid (2NPA) is a modifying agent that has been used in the modification of carboxyl groups. It can react with nucleophiles to form adducts and with carbodiimides to form ureas. 2NPA reacts with amino acids, peptides, and other nitrogenous compounds at their carboxyl groups to form ester or amide bonds. The nature of the residues after modification varies depending on the nature of the carboxyl group that was modified.

2,2-Dimethyl-4-pentenoic acid is a decarboxylating agent that converts the carboxylic acid group to an aldehyde. It is commonly used as a reducing agent in organic synthesis, especially for the conversion of esters and nitriles to alcohols and amines respectively. The synthesis of 2,2-dimethyl-4-pentenoic acid is achieved by reacting piperidine with propylene oxide. This reaction proceeds via a six-membered ring intermediate that decomposes to form the final product. The reaction can be catalyzed with peroxide or hydrogen peroxide, which leads to a high yield. 2,2-Dimethyl-4-pentenoic acid has been shown to be effective against hyperproteinemia and lipogenous disorders such as steatosis and cholestasis.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-(2-Methylphenyl)-3-thiosemicarbazide is a crystalline solid that belongs to the group of benzoic acid derivatives. It has an orthorhombic crystal structure, with a yellow color. The crystals are measured at room temperature, and it has an atomic weight of 197.11 g/mol. 4-(2-Methylphenyl)-3-thiosemicarbazide is stable in air and in solution, but decomposes at temperatures above 250°C. This compound has been studied by using X-ray diffraction measurements and Bruker parameters. Its isotropic radiation is recorded at the following wavelength: 1.5418 Å (1).

Versatile small molecule scaffold

2-[Benzyl(methyl)ao]propanoic acid is a glycine analogue that has been synthesized and characterized. It is an α-amino acid with the chemical formula C5H11NO2. The molecule has a chiral carbon atom at the center of the propanoic acid group and contains two asymmetric carbon atoms on the benzene ring, which enable it to exist in two stereoisomers. The compound has been shown to exhibit interligand interactions with copper as well as stereoselectivity in its interactions with l-amino acids. 2-[Benzyl(methyl)ao]propanoic acid also exhibits dichroism spectra, which are unique to these types of molecules.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.