Building Blocks

Versatile small molecule scaffold

N-(2-Phenylethyl)benzenesulfonamide is a biodegradable and aerobic catalyst that is used in the production of nitrates. It can be recycled and has a high solubility, which allows for efficient extraction from wastewater effluents. The reactor system can be operated at an aerobic or anaerobic conditions. N-(2-Phenylethyl)benzenesulfonamide is soluble in water and can be hydrolyzed by acids or bases to release ammonia gas. The process can also be sustainable due to the use of renewable energy sources such as solar, wind, tidal, or biomass power.

2-[Benzyl(methyl)ao]propanoic acid is a glycine analogue that has been synthesized and characterized. It is an α-amino acid with the chemical formula C5H11NO2. The molecule has a chiral carbon atom at the center of the propanoic acid group and contains two asymmetric carbon atoms on the benzene ring, which enable it to exist in two stereoisomers. The compound has been shown to exhibit interligand interactions with copper as well as stereoselectivity in its interactions with l-amino acids. 2-[Benzyl(methyl)ao]propanoic acid also exhibits dichroism spectra, which are unique to these types of molecules.

Ethyl 2-(indol-3-yl)-2-oxoacetate is a hydroxy derivative of the amino acid tyrosine. It inhibits the enzyme tyrosine hydroxylase, which catalyzes the conversion of tyrosine to L-DOPA. This in turn affects dopamine synthesis and has an inhibitory effect on rat brain. Ethyl 2-(indol-3-yl)-2-oxoacetate also inhibits methylmagnesium borohydride in vitro, which is a reagent that breaks down esters, amides, and nitriles. Tyrosine hydroxylase is inhibited by the presence of two hydroxy groups on the ethyl side chain and one hydroxy group on the indole ring. It can be used as a structural analogue for other drugs that are used to treat Parkinson's disease or depression.

1-Chloro-4-isocyanobenzene (1CI) is an organic compound that has been used as a chemical probe for the detection of amines and other molecules on metal surfaces. The frequency shift in Raman spectra, which is observed after the addition of 1CI to the metal surface, is used to detect amines. 1CI has also been shown to be a potent inhibitor of mitochondrial function. This molecule binds to nucleophilic sites on metal surfaces and forms covalent bonds with them, leading to a high degree of inhibition.
1CI can be synthesized in three steps from commercially available starting materials and is relatively easy to purify.

Versatile small molecule scaffold

Azacycloundecane is a cycloalkane that is used as a solvent. The use of this compound in vivo models has been demonstrated to be useful in the study of drug uptake and distribution, as well as having clinical applications. Azacycloundecane is often used in detergent compositions due to its ability to solubilize fatty acids and inhibit their oxidation. This chemical has also been shown to have low energy, which makes it a suitable candidate for use in osmosis experiments. Azacycloundecane does not react with hydrogen chloride or carbonyl groups. It can be found naturally in fatty acids, amines, benzofuran derivatives, and aliphatic hydrocarbons.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold