Building Blocks
Subcategories of "Building Blocks"
- Boronic Acids & Boronic Acid Derivatives(5,805 products)
- Chiral Building Blocks(1,248 products)
- Hydrocarbon Building Blocks(6,118 products)
- Organic Building Blocks(61,447 products)
Found 208423 products of "Building Blocks"
2,7-Naphthyridin-1(2H)-one
CAS:Cabozantinib is a small molecule that is the first to target VEGFR-2, which is a receptor tyrosine kinase involved in the development of fibrosis. Cabozantinib inhibits the activity of VEGFR-2 by binding to its ATP-binding site and blocking the phosphorylation of downstream signaling pathways. Cabozantinib has been shown to have antifibrotic properties in both preclinical and clinical models. The drug candidate has been shown to reduce kidney fibrosis in animal models. The standard dose for cabozantinib was found to be 5 mg/kg, with a maximum tolerated dose of 20 mg/kg. In vitro studies have indicated that cabozantinib binds with high affinity to the ATP-binding pocket of VEGFR-2, exhibiting competitive inhibition against other kinases such as PDGFR-beta and cKit, as well as diaryliodonium (a specific inhibitor). Caboz
Formula:C8H6N2OPurity:Min. 95%Molecular weight:146.14 g/mol6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one
CAS:Versatile small molecule scaffold
Formula:C8H6BrNO2Purity:Min. 95%Molecular weight:228.04 g/mol(3-Aminopropyl)(3-phenylpropyl)amine
CAS:Versatile small molecule scaffoldFormula:C12H20N2Purity:Min. 95%Molecular weight:192.3 g/mol1-(Difluoromethyl)-1H-pyrazole-4-carbaldehyde
CAS:Versatile small molecule scaffoldFormula:C5H4F2N2OPurity:Min. 95%Molecular weight:146.09 g/molMethyl 2-(2-chloropyrimidin-4-yl)acetate
CAS:Versatile small molecule scaffold
Formula:C7H7ClN2O2Purity:Min. 95%Molecular weight:186.59 g/mol5-Chloro-1-methyl-1H-pyrazol-3-amine
CAS:Versatile small molecule scaffold
Formula:C4H6N3ClPurity:Min. 95%Molecular weight:131.56 g/mol3,3-Diethoxypropan-1-amine
CAS:3,3-Diethoxypropan-1-amine is a synthetic drug that reversibly inhibits the growth of bacteria. It has been shown to be effective against methicillin resistant strains of Staphylococcus aureus and Clostridium perfringens, with no detectable activity against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. 3,3-Diethoxypropan-1-amine is a heterobifunctional compound that binds to epidermal growth factor with high affinity. 3,3-Diethoxypropan-1-amine can also bind to collagen and liposomal formulations, which may be useful for the treatment of wounds. This drug has been shown to inhibit δ opioid receptors in mice and rats, which is thought to contribute to its analgesic effects.Formula:C7H17NO2Purity:Min. 95%Molecular weight:147.22 g/molThiophen-3-ylmethanamine hydrochloride
CAS:Versatile small molecule scaffold
Formula:C5H8ClNSPurity:Min. 95%Molecular weight:149.64 g/molN-Carbethoxy-4-hydroxypiperidine
CAS:N-Carbethoxy-4-hydroxypiperidine is a drug substance that is a h1 receptor antagonist. It is used as an antihistamine to treat the symptoms of hay fever and other allergic reactions. N-Carbethoxy-4-hydroxypiperidine is available in two enantiomers, or mirror images, which are labelled S and R. The R enantiomer is more potent than the S enantiomer for inhibiting histamine h1 receptors. This drug has been shown to inhibit the growth of tuberculosis bacteria in cell culture and animal models, but not against Mycobacterium avium complex. N-Carbethoxy-4-hydroxypiperidine has also been shown to have significant antibacterial activity against Clostridium perfringens with minimal toxicity in mice.
Formula:C8H15NO3Purity:Min. 95%Molecular weight:173.21 g/molDSP-4 hydrochloride
CAS:DSP-4 hydrochloride is a neurotoxin that inhibits the synthesis of norepinephrine. It binds to neurons and prevents the uptake of dopamine, which can lead to neuronal death. DSP-4 hydrochloride affects brain functions by decreasing the concentration of serotonin in the cortex and increasing the concentrations of norepinephrine in the coeruleus. DSP-4 hydrochloride also has estrogenic effects by binding to estrogen receptors and increasing estradiol benzoate concentrations.Formula:C11H16BrCl2NPurity:Min. 95%Molecular weight:313.06 g/molMethyl 4-chlorobenzenesulfonate
CAS:Versatile small molecule scaffold
Formula:C7H7ClO3SPurity:Min. 95%Molecular weight:206.65 g/mol2,4-Dichloro-6-(propan-2-yl)pyrimidine
CAS:Versatile small molecule scaffold
Formula:C7H8Cl2N2Purity:Min. 95%Molecular weight:191.05 g/moltert-Butyl oxazol-4-ylcarbamate
CAS:Versatile small molecule scaffoldFormula:C8H12N2O3Purity:Min. 95%Molecular weight:184.19 g/mol4-{[(tert-butoxy)carbonyl]amino}bicyclo[2.2.2]octane-1-carboxylic acid
CAS:Versatile small molecule scaffoldFormula:C14H23NO4Purity:Min. 95%Molecular weight:269.3 g/mol1,2,3,4-Tetrahydro-1,7-naphthyridine
CAS:Versatile small molecule scaffoldFormula:C8H10N2Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:134.18 g/mol4-bromo-1H-pyrazole-5-carbaldehyde
CAS:Versatile small molecule scaffoldFormula:C4H3BrN2OPurity:Min. 95%Molecular weight:175 g/molTert-Butyl 2-(Trifluoromethyl)Piperazine-1-Carboxylate
CAS:Versatile small molecule scaffoldFormula:C10H17N2O2F3Purity:Min. 95%Molecular weight:254.24 g/moltert-Butyl 3-(trifluoromethyl)piperazine-1-carboxylate
CAS:Versatile small molecule scaffold
Formula:C10H17F3N2O2Purity:Min. 95%Molecular weight:254.25 g/mol(R)-2-(N-Boc-aminomethyl)morpholine
CAS:Versatile small molecule scaffoldFormula:C10H20N2O3Purity:Min. 95%Molecular weight:216.28 g/mol2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride
CAS:2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride is a lead compound that belongs to the family of pyridine derivatives. It has been shown to be a potent inhibitor of bacterial RNA synthesis, with an IC50 value of 1.2 μM for Escherichia coli and 8 μM for Bacillus subtilis. 2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride also inhibits the growth of Gram negative bacteria such as Pseudomonas aeruginosa and Enterobacter cloacae. The compound binds to the nucleophilic site on ribosomes, which prevents the formation of peptide bonds between amino acids in protein synthesis. This leads to cell death by inhibiting protein synthesis, leading to cell division.Formula:C8H11Cl2NOPurity:Min. 95%Molecular weight:208.08 g/mol
![4-{[(tert-butoxy)carbonyl]amino}bicyclo[2.2.2]octane-1-carboxylic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNJB30476.webp&w=3840&q=75)
