Building Blocks

Applications 2-(Bromomethyl)benzonitrile is an intermediate in the synthesis of Alogliptin (A575425), an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lai, Z., et. al.: Eur. J. Med. Chem., 83, 547 (2014); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009)

Applications 5-Hydroxy-N-methyl-2-pyrrolidinone is a metabolite of N-methylpyrrolidone (NMP).
References Payan, J., et al.: Drug Metab. Dispos., 30, 1418 (2002), Carnerup, M., et al.: Food Chem. Toxicol., 43, 1441 (2005), Angerer, J., et al.: Toxicol. Sci., 93, 3 (2006),

Applications HYDROXYMALONIC ACID (cas# 80-69-3) is a useful research chemical.

Applications 4-(3-HYDROXYPROP-1-EN-1-YL)-2-METHOXYPHENOL (cas# 458-35-5) is a useful research chemical.

Stability Hygroscopic
Applications Hydrazine hydrochloride (cas# 2644-70-4) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 4-​Hydrazinobenzoic acid hydrochloride (cas# 24589-77-3) is a useful research chemical.

Applications 3-Bromothiofuran is a compound used as a corrosion inhibitor in mild steel. It also shows antimicrobial activity against common bacterium types such as Escherichia coli and Bacillus subtillis.
References Sawkar, A. et al.: Proc. Nat. Acad. Sci., 99, 15428 (2002); Cox, T. et al.: Lancet, 355, 1481 (2000);

Applications 2-Hydroxy-5-methylpyridine (cas# 1003-68-5) is a useful compound for organic synthesis. In particular it has been used for the diastereoselective preparation of cyclobutane-fused pyridinyl sulfonyl fluorides.
References Liu, J., et al.: Org. Biomol. Chem., 18, 4019 (2020)

Applications Hydroxymethyl Ivacaftor is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.
References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)

Applications A metabolite Methaqualone (M225900). Controlled substance.
References Ericsson, O., et al.: Acta Pharmaceut. Suecica, 15, 81 (1978), Wilson, K., et al.: Eur. J. Drug Metab. Pharmacokinet., 9, 301 (1984),

Applications 2-Hydroxy-3-methylbutyric Acid is a α-hydroxylated butyric acid derivative used as a marker in chemical diagnosis of organic aciduria and other inborn errors. 2-Hydroxy-3-methylbutyric Acid is also used as a metabolomic biomarkers in preeclampsia.
References Nakagawa, K. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 878, 942 (2010); Kenny, L.C. et al.: Reprod. Sci., 15, 591 (2008); Garcia, A. et al.: Clin. Chem., 44, 1905 (1999);

Applications 2-Hydroxyisobutyric Acid is used as a reagent in the preparation of fully functionalized tetronic acids. Also used in the synthesis of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides which display anticonvulsant activity.
References Prousis, K., et al.: Tetrahedron, 71, 8637 (2015); Pastore, V., et al.: Bioorgan. Med. Chem., 21, 841 (2013);