Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Bromo-2-(2-ethoxyethoxy)ethane is a triazolium ionic liquid that is used as an organic solvent. It has been shown to be a nucleophilic reagent and to react with carbonyl compounds such as benzyl. This compound can also be used as a transition-metal catalyst for the synthesis of organic compounds and yields high densities in solvents. 1-Bromo-2-(2-ethoxyethoxy)ethane can also be used to synthesize functionalized halides, such as fluoride or halides, by reacting with chlorine or other halogens.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4,5,6-Trimethylpyrimidin-2-amine is a human immunodeficiency virus (HIV) type 1 inhibitor that is currently in the early stages of development. It has shown antiviral activity against HIV type 1 strains and cytotoxicity against HIV-infected cells. In vitro studies have shown that 4,5,6-trimethylpyrimidin-2-amine inhibits the HIV transcriptional elongation factor TFIIS by binding to the enzyme. This inhibition leads to a decrease in viral RNA synthesis and consequently a decrease in virus production.</p>

<p>Versatile small molecule scaffold</p>

<p>1,8-Naphthyridin-4-ol is a synthetic compound with anti-inflammatory and pain relieving properties. It is used as an intermediate in the preparation of 1,8 naphthyridine and other compounds. This drug has been shown to have antiviral activity against herpes simplex virus type 2 in cell cultures. It also has been shown to be effective for the treatment of colitis and respiratory diseases, such as asthma. 1,8-Naphthyridin-4-ol inhibits the production of inflammatory cytokines by blocking cyclooxygenase (COX) enzymes. In addition, this compound may have antidepressant effects due to its ability to inhibit monoamine oxidase (MAO).</p>

<p>1,8-Naphthyridin-4-amine is a genotoxic compound that has been detected in human glioblastoma cells. It can be used to investigate the molecular mechanism of cancer and the carcinogenesis process. 1,8-Naphthyridin-4-amine binds to DNA polymerase and inhibits its activity, which prevents the replication of DNA. This drug also induces p53 activation and increases chloride levels in cancer cells. 1,8-Naphthyridin-4-amine has also been shown to cause DNA repair by base excision.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(4-Methoxybenzyl)urea is a nitrosourea that inhibits the production of nitric oxide. It has been shown to inhibit the formation of peroxynitrite and nitrous oxide, which are products of the reaction between superoxide and nitric oxide. 1-(4-Methoxybenzyl)urea is also capable of inhibiting aerobic respiration in bacteria, by binding to anions such as bicarbonate. This drug has been shown to inhibit the oxidation of formaldehyde by oxidoreductases and form compounds with other aromatic amines.</p>

<p>Versatile small molecule scaffold</p>