Building Blocks

<p>4-Ethylamino-1-butanol is an alkanolamine that interacts with receptors in the body. It has a hydroxyl group and is a molecule that contains functionalities. It interacts with other molecules, such as corticotropin-releasing hormone (CRH). 4-Ethylamino-1-butanol binds to CRH and prevents it from binding to its receptor, which decreases the release of corticotropin. This compound has been used as a positron emission tomography (PET) radiotracer for imaging the insulin receptor in living tissue. The chemical can be systematically introduced into tissues and organs, including the brain, where it accumulates due to its hydrophilic nature. 4-Ethylamino-1-butanol also has oxygenated groups that are suitable for PET imaging using 18F radiolabeling.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Nitro-1,2,3,4-tetrahydroquinoline is an amine that is used in the synthesis of other chemicals. It is selective for transfer reactions because it can transfer to sulfate. The reaction selectivity is determined by the module and the reaction solution. The efficiency of the carbenium ion can be increased by adjusting the pH to make it more acidic. 5-Nitro-1,2,3,4-tetrahydroquinoline has a high yield and can be synthesized with a high degree of purity by using ammonium sulfate as a transfer agent in a neutral solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Dichloro-2-nitrophenol is a chemical that is used as an immunomodulator, pesticide, or herbicide. It is activated by the body to form a reactive intermediate that can bind to DNA and create mutations. 5-Dichloro-2-nitrophenol has been shown to cause oxidative damage in cell cultures and other tissues, such as proximal tubules of the kidney. It also produces malondialdehyde oxidation products which are known to be cytotoxic. In addition, preincubation with 5-Dichloro-2-nitrophenol increases the sensitivity of cells to other oxidative stressors such as peroxides and hydrogen peroxide.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-N-Benzyl-4-chlorobenzene-1,2-diamine is a chemical compound that is used as an anticancer drug. It is a potent inhibitor of protein kinase C and has been shown to induce cell cycle arrest in the G1 phase of the cell cycle. 1-N-Benzyl-4-chlorobenzene-1,2-diamine also induces apoptosis in cancer cells. The cytometric analysis of apoptotic processes was used to determine the pharmacokinetic properties of 1-N-Benzyl-4-chlorobenzene-1,2-diamine. This drug may be mediated by annexin A5 or other proteins. Radionuclide imaging studies were conducted in order to assess the pharmacokinetics of 1NBDBCD in humans.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 4-sulfanylbutanoate is a leukotriene D4, which is an inflammatory mediator. It can be activated by the addition of hydrogen peroxide or tetrahydropyran and then becomes a potent leukotriene antagonist. Methyl 4-sulfanylbutanoate also inhibits the activity of acyltransferases, which are enzymes that catalyze reactions in the synthesis of arachidonic acid. This compound has been shown to have inhibitory effects on inflammatory bowel disease and may be useful for treating cerebral inflammation.</p>