Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2,4-Dimethylaniline hydrochloride is a nitrogen containing compound that can be found in the environment. It has been shown to have antimicrobial activity against gram-positive bacteria and fungi. The mechanism of 2,4-dimethylaniline hydrochloride is through the transfer of electrons from cytochrome c oxidase to molecular oxygen (O2). This electron transfer results in the oxidation of 2,4-dimethylaniline hydrochloride and the reduction of molecular oxygen (O2) to water (H2O). 2,4-Dimethylaniline hydrochloride also has a basic structure with two nitrogen atoms that are able to form intermolecular hydrogen bonding interactions. The matrix effect may have an impact on the analytical method used for this compound. The kinetic studies were done at low temperature and high concentrations. Solid phase microextraction was used as an analytical method for this compound. Coordination geometry was not discussed in this article

3-Methyl-3-phenylbutan-1-ol is an intramolecular compound that has a cationic center. It is the result of cycloalkylation of phenyl group with a deuterium atom at the 3 position of the molecule. The cationic center can be substituted with other alkyl groups to form isomeric compounds. 3-Methyl-3-phenylbutan-1-ol can also be synthesized using deuterated cations in place of hydrogen ions, which are called deuterated compounds.

Ethyl 4-nitro-1-phenyl-1H-pyrazole-3-carboxylate (NPC) is a potent and selective antagonist of the a3 adenosine receptor. It binds to the receptor with high affinity and has been shown to inhibit adenosine-mediated activation of the phosphoinositide 3 (PI3) kinase pathway. NPC is in preclinical development for use as an antihypertensive agent, and has also been investigated as a potential treatment for asthma.

Versatile small molecule scaffold

Versatile small molecule scaffold

5,6-Dimethyl-4-nitro-1H-1,3-benzimidazole is a photoactive compound that reacts with ultraviolet light to form photoproducts. It has a strong absorption band at 335 nm and can be used as a reference in spectroscopic analysis. The compound has been shown to react with methanol in the presence of light to produce hydrogen cyanide and formaldehyde. 5,6-Dimethyl-4-nitrobenzimidazole can also react with water to produce hydrogen cyanide and formaldehyde.