Building Blocks

<p>Versatile small molecule scaffold</p>

<p>1-Oxo-1,2-dihydroisoquinoline-3-carboxylic acid (ODHC) is a synthetic compound that has been shown to have anti-tumor activity in mouse melanoma cells. ODHC inhibits the production of aldehydes through the interaction with thiourea and homophthalic acid. ODHC also binds to topoisomerase II, which prevents the unwinding of DNA and limits DNA replication. This leads to cell death by inhibition of DNA synthesis. ODHC has been shown to be photostable and has a low toxicity for healthy cells. It is also able to chelate metal ions, such as iron, copper, or zinc, which are important for cancer cell growth and proliferation.</p>

<p>4-Phenyl-1H-pyrazole-3-carboxylic acid is a chiral, alkoxycarbonyl, regulator that has been used agriculturally as a growth regulator and weed control. It can be used in the form of an alkyl ester or carbonic ester. It has been shown to have active oxygen and hydrochloric acid which are responsible for its regulatory properties. 4-Phenyl-1H-pyrazole-3-carboxylic acid has been shown to be effective against weeds like Triazole resistant weeds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,6-Dimethyl-1,4-dihydropyridin-4-one is an organic acid that is used as a surface active agent. It has been shown to have coccidiosis in poultry and can be recycled from reaction solutions. 2,6-Dimethyl-1,4-dihydropyridin-4-one reacts with hydrochloric acid to form salicylic acid and hydrogen chloride gas. Impurities are removed by ion exchange or activated charcoal. Chlorine gas is added to neutralize the solution of 2,6-dimethylpyridine 4-one and convert it into salicylic acid. Finally, the solution is chlorinated to remove any remaining impurities. The organic solvent is then evaporated off and 2,6-dimethylpyridine 4 one crystals are left behind.</p>

<p>1,2,5-Trimethylpiperidin-4-one is an active substance that belongs to the class of benzofuran derivatives. It has been shown to be a potent inhibitor of the enzyme oxalate oxidase and has been used in the synthesis of analogs. The tautomeric form of 1,2,5-trimethylpiperidin-4-one is its enol form with an oxime group on the alpha carbon atom. This molecule can react with ethyl bromoacetate in a condensation reaction to produce an amide derivative.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Cyclopropylmethyl)piperazine is a drug that has been used to treat deficiencies of pyruvate kinase, which is an enzyme needed for the metabolism of pyruvate. It has also been used to treat hemisulfate deficiency and is currently being studied as a potential treatment for metabolic disorders such as diabetes. 1-(Cyclopropylmethyl)piperazine is an amorphous form of the drug that can be administered orally or intravenously. This crystalline form can be administered by injection and is often given with glucose to increase absorption.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-1,3-diisopropylbenzene is an organic compound that belongs to the group of sulfamic acids. It has been shown to inhibit hypercholesterolemia and cholesterol absorption in rats. The mechanism of action of 2-bromo-1,3-diisopropylbenzene is not well understood but may involve inhibition of the enzyme HMG-CoA reductase. This drug has also been shown to have a photophysical activity and can be used as a light emitting material in devices such as organic light emitting diodes (OLEDs). 2-Bromo-1,3-diisopropylbenzene can also be used for the synthesis of phosphane ligands and Grignard reagents.</p>

<p>Versatile small molecule scaffold</p>