Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

2-Methyl-6-phenylpyridine-3-carboxylic acid is a compound that has been used as an antimicrobial agent. It is the most active of the aldehydes for the treatment of tuberculosis. 2-Methyl-6-phenylpyridine-3-carboxylic acid inhibits bacterial growth by binding to DNA dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2 methyl 6 phenylpyridine 3 carboxylic acid also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>3-Bromo-6-methylquinoline is a helical molecule with an axial arrangement of methyl groups around the central benzene ring. It has been shown to undergo racemization in aqueous solution, and the helicenes are photoproducts from the reaction. The photophysical properties of 3-bromo-6-methylquinoline have been studied extensively and it is found to be a good candidate for applications in organic light emitting diodes and solar cells. Computational studies have shown that 3-bromo-6-methylquinoline is a potential substrate for alkylation reactions with pyridinium ions and may be used as a catalyst.<br>Helix molecules are composed of repeating units called turns or residues. Each turn consists of two parts: one part which runs up the center of the helix, called the backbone; and one part which runs down the outside edge, called the side chain. The backbone is always made</p>

<p>Versatile small molecule scaffold</p>

1,5-Dimethyl-1H-indole-2,3-dione is a molecule with antibacterial activity. It has been shown to have interactions with staphylococcus and subtilis strains. Computational results show that the molecule has inhibitory effects on bacterial dna gyrase and topoisomerase IV. This inhibits the synthesis of bacterial proteins and leads to cell death. Hydrazides have been shown to be effective against staphylococcus aureus isolates and are hypothesized to inhibit protein synthesis by binding to bacterial ribosomes. The mechanism of action of 1,5-dimethyl-1H-indole-2,3-dione is not yet known.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

N-Butyl-4-nitrobenzenesulfonamide is a chemical compound that belongs to the group of nitro compounds. It is synthesized by the reaction of an aliphatic amine with nitrobenzenesulfonyl chloride. The structure of this compound is characterized by an electron-deficient phenyl ring, which can be protonated and form a radical anion. N-Butyl-4-nitrobenzenesulfonamide has been shown to yield nitrated aliphatic amines, such as 3-nitropropane sulfonamide, when treated with sodium nitrate in dilute sulfuric acid. This chemical reaction occurs through radical ion mechanisms and involves the cleavage of a bond between two carbon atoms.