Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Dimethyl 2,4-dibromoglutarate is a stereospecific, unselective opioid receptor ligand. It interacts with the opioid receptors and has been shown to have affinity for both mu and kappa receptors. Dimethyl 2,4-dibromoglutarate has been studied as a potential model for morphine and other selective ligands. The two enantiomers of dimethyl 2,4-dibromoglutarate were synthesized in order to study their selectivity for the opioid receptor. The racemic mixture of dimethyl 2,4-dibromoglutarate was found to be more potent than either of the individual enantiomers. The cyclopropane ring on the left side of the molecule is responsible for this effect. This ring confers higher affinity and selectivity than that on the right side of the molecule.</p>

<p>Versatile small molecule scaffold</p>

<p>Formaldehyde Sodium Bisulfite is an aqueous solution of formaldehyde and sodium bisulfite. It is used as a disinfectant in the treatment of wastewater, including sewage and other industrial effluents. Formaldehyde Sodium Bisulfite is also used as a detergent additive to prevent the formation of acid in detergent compositions. This product can be used in analytical methods to determine the presence of formaldehyde and dimethyl fumarate by mass spectrometry (LC-MS/MS). Formaldehyde Sodium Bisulfite can also be utilized in glycol ester polymerization reactions, where it acts as an epidermal growth factor (EGF) receptor antagonist.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5,5-Dimethyl-1,3-dioxane is a byproduct of the polymerization reaction between ethylene oxide and propylene oxide. It is used in wastewater treatment to remove organic pollutants. 5,5-Dimethyl-1,3-dioxane reacts with benzene to form dioxanes and yields of dioxanes are increased when phenyl groups are present. The conformation of 5,5-Dimethyl-1,3-dioxane is cyclic and it can react with terephthalic acid or alcohols to form telomerization products. When reacted with oxygen atoms from air, 5,5-Dimethyl-1,3-dioxane will create organic compounds such as ethers or esters.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,2,4-Triazolo[1,5-a]pyridin-2-amine is an organic compound that is a member of the heterocyclic aromatic amine class. It has been shown to be a potent inhibitor of Jak2 kinase. 1,2,4-Triazolo[1,5-a]pyridin-2-amine is also capable of inhibiting inflammatory responses by reducing the production of proinflammatory cytokines. The compound has been shown to be an effective treatment for autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.</p>

<p>Versatile small molecule scaffold</p>

<p>1-cyclohexylidenepropan-2-one is a carboxylic acid that is used in the synthesis of medicines and other organic compounds. It has been shown to have antioxidant, anti-inflammatory, and hypocholesterolaemic properties. 1-cyclohexylidenepropan-2-one is also used as a pheromone in insects.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methyl-piperazin-1-yl)-acetonitrile (4MPAN) is a synthetic compound that is used as an intermediate in the production of pharmaceuticals. It is a reaction rate accelerator and a dehydration agent. 4MPAN has been shown to be stereoselective, reacting faster with one enantiomer than with the other. It also reacts with halides and inorganic compounds. 4MPAN has been extensively studied for its biological properties, including potent antibacterial activity against staphylococcus and cyanides. This compound also reacts with amines, which may account for its antibacterial activity.</p>

<p>Versatile small molecule scaffold</p>