Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Octane-1-sulfonamide (OSA) is a glycol ether that is used as a reagent for biological samples. It reacts with the hydroxyl group on proteins, which causes the compounds to become more hydrophobic and interact with each other. The OSAs are also reactive with fatty acids, which leads to cross-linking of cell membranes. This interaction may be related to the low light activity of OSA. Octane-1-sulfonamide can also bind cationic polymers, which may be useful in ophthalmic drugs.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,6-dichloropyridine-3-carboxylate is a carboxylic acid that can be synthesized by reacting 2,6-dichloropyridine with an acetyl chloride. It has been used in the synthesis of dopamine D2 receptor antagonists. The sulfoxide group in this compound may undergo alkaline hydrolysis to yield an anion and a nucleophilic adduct. This carboxylic acid also reacts with triethylamine to form esters. In addition, methyl 2,6-dichloropyridine-3-carboxylate is regioselective for the alpha position when it reacts with methyltetrahydrofuran.</p>

<p>6-Chloro-2-methoxynicotinic acid is a ketone that reacts with chlorine in the presence of light to form chlorinated products. It is a versatile intermediate for the synthesis of various compounds. 6-Chloro-2-methoxynicotinic acid is used in the synthesis of naphthacene, which is a precursor to dyes and pharmaceuticals. The reactivity of this compound depends on substituents located at the 2 position. Substituents cause sterically hindering effects and lead to different geometries and reactivities, such as attack by chlorine or substitution by hydrogen.</p>

<p>2-Methoxy-4,6-dimethylnicotinonitrile is a photoreactive compound that reacts with UV light to produce an adduct. The 1-cyanonaphthalene group in 2-methoxy-4,6-dimethylnicotinonitrile undergoes a photochemical reaction to form an adduct with the benzene ring. It is postulated that the dimer and x-ray structural analysis of 2-methoxy-4,6-dimethylnicotinonitrile are stable and pyridine can be used as a solvent.</p>

<p>2-Amino-4-(aminooxy)butanoic acid dihydrochloride is a cyclization product of the antibiotic cycloserine. It has been synthesised from 2-amino-4-oxobutanoic acid by the addition of hydrochloric acid and then heated to reflux for 20 hours. The purity of this product is &gt;98%.<br>2-Amino-4-(aminooxy)butanoic acid dihydrochloride has been shown to be a homologue of canaline, which is an antibiotic used in the treatment of tuberculosis. This compound also has antibacterial activity, although it is less potent than cycloserine.</p>

<p>(2E,4E)-Hepta-2,4-dienoic acid is an organic compound that belongs to the group of quinoline derivatives. It is a colorless liquid at room temperature and is soluble in organic solvents. This compound can be used as a dehydrohalogenating agent in the synthesis of mappicine and camptothecin derivatives. (2E,4E)-Hepta-2,4-dienoic acid can also react with ketocarboxylic acids to form carotenoid compounds. The chemical formula for this molecule is C8H10O3.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>