Building Blocks

<p>2-Ethylcyclohexanol is a hydrogen peroxide catalyst that has been implemented in nanocomposites for use as electrodes. This multifunctional material is a transition metal oxide with properties of being acidic and able to catalyze the oxidation of organic pollutants. 2-Ethylcyclohexanol has also been shown to be efficient in mineralizing (oxidizing) transition metals such as Fe(II) or Cr(III). This chemical can be used to remove toxic heavy metals from water, and it can be analyzed using techniques such as voltammetry, cyclic voltammetry, and electrochemical impedance spectroscopy. 2-Ethylcyclohexanol can be used as an inexpensive hydroxyl radical generator. It is commercially available in the cis- and trans- mixture.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Methylcycloheptanol (1MCH) is a polydimethylsiloxane with a molecular weight of about 370. The catalytic activity of 1MCH is due to the presence of two double bonds in the molecule. The 1-methylcycloheptanol can be used for the synthesis of iodides and for the degradation of headspace volatile compounds, such as dichlorocarbene and dihalocarbenes. It has been shown to have affinity towards certain unsaturated ketones, such as oxoalkyl and unsaturated ketones. 1-Methylcycloheptanol has also been found to be able to extract cirsium setidens from soil samples using microextraction methods.</p>

<p>Versatile small molecule scaffold</p>

<p>1,2,5-Thiadiazole-3,4-dicarboxylic acid is a dicarboxylic acid that is structurally related to the thiadiazole ring. It has been shown to interact with amines and hydrate in humid conditions. The crystal structure of 1,2,5-thiadiazole-3,4-dicarboxylic acid has been determined by x-ray diffraction. The molecule forms a mononuclear complex with chloride ions in the crystal system called the cycloaliphatic motif. 1,2,5-Thiadiazole-3,4-dicarboxylic acid has also been found to form hydrogen bonds with temperatures in the range of −10°C and 30°C.</p>

Versatile small molecule scaffold

<p>4-Allyl-3-thiosemicarbazide is a copper complex that inhibits the growth of cancer cells. Copper chloride is an important catalyst for this reaction. The coordination geometry of the copper ion and the structure of the product are key factors in determining its cytotoxicity. This compound has been shown to have significant cytotoxicity against a variety of cancer cell lines, including leukemia, lymphoma, breast, prostate, lung, pancreatic and colon cancer cells. 4-Allyl-3-thiosemicarbazide is also able to inhibit kinesin by binding to its ATPase site and preventing it from transporting cargo along microtubules.</p>

<p>3-Methylpiperidin-2-one is a hydroxylated piperidine derivative that can be synthesized by the reaction of xylene with triphosgene in the presence of an acid hydrazide. This compound has been shown to have antibacterial activity against Streptococcus faecalis and other bacteria, but it is carcinogenic in rats. 3-Methylpiperidin-2-one has been used as a ligand for metal ions such as copper and nickel. It can be synthesized using methods like alkylation or chiral synthesis with five membered rings.</p>

<p>Bis(dimethylamino)dimethylsilane (Bis-DMAS) is a silylating agent that reacts with the hydroxy groups of siloxanes to form a cross-link. It can be used as a functional group for the synthesis of polymers, coatings, and adhesives. Bis-DMAS has also been used to improve the reactivity of other functional groups, such as carbonyls, amines, nitriles, and epoxides. It is reactive in air and moisture and should be stored in an inert atmosphere. Bis-DMAS reacts with metal surfaces to form a coating by reacting with both the metal surface and hydrogen atoms on the surface. The reaction temperature is dependent on the substrate: higher temperatures are needed for copper than aluminum due to copper's higher reactivity. The activation energies are different for each reaction type: thermal reactions have an activation energy of 40 kJ/mol while electrochemical reactions have an activation energy of</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-5-methoxybenzyl bromide is a cyclization agent that is used in the synthesis of tetracyclines, polyphosphoric acid, and tetralones. It is typically used as a catalyst for cyclization reactions involving aromatic rings. This agent reacts with phosphorus oxychloride to produce polyphosphoric acid. Polyphosphoric acid can be used to synthesize tetracyclines and tetralones. 2-Chloro-5-methoxybenzyl bromide also acts as an oxidizing agent that converts primary alcohols into carboxylic acids and secondary alcohols into ketones or aldehydes.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,2-Dimethyl-chroman-4-one is a synthetic compound that has been shown to be an antibacterial agent. It is active against many Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis. 2,2-Dimethyl-chroman-4-one also inhibits the activation of the MAP kinase pathway and the synthesis of protein kinase C. The irradiation of 2,2-dimethylchroman-4-one produces a compound which has been shown to have antiinflammatory effects on mesenchymal stromal cells.</p>

<p>Ethyl 4-hydroxy-3-methyl-1-benzofuran-2-carboxylate (EHMC) is an oxadiazole compound that has been shown to be toxic to the central nervous system. It is a tetraacetate ester of the compound and it has been shown to induce death in mice. EHMC has also been observed to produce thionyl chloride, aldehydes and dehydrogenation products in tissue samples. Elution profiles of EHMC from liquid chromatography have shown that this chemical can be quickly metabolized by methylation and subsequent degradation into benzofuran derivatives. The heterozygote for this compound is known for its ability to metabolize carbohydrates more efficiently than normal individuals.</p>

<p>4-Hydroxy-3-methyl-1-benzofuran-2-carboxylic acid (4HMBF) is an antifungal agent that belongs to the group of phenylacetic acid derivatives. It has been shown to have antifungal activity against Candida albicans and other fungal species. 4HMBF incorporates into the fungal cell wall by reacting with the chain, which may inhibit protein synthesis. The biological properties of 4HMBF are not yet fully understood. It has been found to be a lead compound for future drug design.</p>