Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Ethyl-4-bromo-benzenamine is a preorganized molecule with a covalent amide bond that is stabilized by interactions with the macrocyclic moiety. The helical conformation of this molecule is stabilized by its substructures, which are the two N-ethyl groups and the bromine atom. The helicity of this compound is high, and it has been shown to have a yield of 100%.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Vanillic acid is a phenolic compound that can be found in vanilla and other plants. It is an important precursor for the synthesis of aromatic compounds such as ferulic acid, lignin, and coumarin. Vanillic acid has been shown to have a variety of biochemical and chemists properties, including the ability to aromatize, which means it can be used in the preparation of synthetic hormones. This compound also acts as an antioxidant by scavenging reactive oxygen species. Vanillic acid is found in two sources: pre-existing vanillin (from plants) and ferulic acid (from microbial metabolism). Vanillin is derived from coniferyl alcohol and coniferaldehyde, which are both found in poria. Ferulic acid is produced by polyporus fungi and can be converted into vanillic acid via decarboxylation.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Benzenesulfonyl)propan-2-ol is a chiral, neutral compound that is used as a heterofunctional catalyst. It is an electrophilic catalyst that can be used to catalyze hydroboration reactions. 1-(Benzenesulfonyl)propan-2-ol binds to the substrate with two bidentate interactions and participates in the reaction by donating electron density from the nitrogen atom of an allylic position. This compound is also capable of catalyzing catecholborane oxidation reactions, which are important for the synthesis of pharmaceuticals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>2-Phenyl-1H-imidazole-4-carbaldehyde is an aldehyde that is used as a ligand in asymmetric synthesis. It can be used in the nitroaldol reaction to produce chiral imidazole derivatives. The compound is useful for the synthesis of molecules with high molecular weight and low reactivity, which can be further modified to produce pharmaceuticals. The compound has been shown to catalyze organic reactions, such as condensation products and stereospecific reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,2-dimethylpropanecarboximidate hydrochloride is a synthetic chemical that has been used as a reagent in organic synthesis. It was first developed in the early 1940s and was found to have hypotensive properties. The drug is a competitive inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinase. Methyl 2,2-dimethylpropanecarboximidate hydrochloride is structurally related to benzimidazole derivatives and thiones. It has an aromatic heterocyclic structure with two nonpolar groups at opposite ends of the molecule.</p>

<p>Versatile small molecule scaffold</p>