Building Blocks

<p>Dimethyl-piperidin-2-ylmethyl-amine (DMPM) is a chemical compound that is known to inhibit activation pathways of NF-κB. DMPM is a selective inhibitor of the activation pathway of NF-κB, and has been shown to reduce inflammation in mouse models. It also inhibits receptor-mediated pathways, which are involved in the activation of antigen presenting cells. DMPM has been shown to be effective in inhibiting chronic inflammation and autoimmunity. This drug has been found to inhibit the inflammatory response by preventing the production of cytokines such as TNF-α, IL1β, IL6, and IFNγ. The chemical structure of DMPM has been shown to be stable enough for screening purposes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4,6-Dimethylisothiazolo[5,4-b]pyridin-3(2H)-one is a crystalline compound that belongs to the group of p2 molecules. This molecule has an electron density of 0.071 e/Å and a molecular weight of 172.14 g/mol. The tautomeric form is the most stable, with a geometry of C2v and a density of 1.8 g/cm3. The substituents are phenyl rings and methyl groups that have a molecular structure with the following constants: Torsion angle (χ) = -7°; Diameter (D) = 2.8 Å; Distance (d) = 2.4 Å; Length (l) = 3.9 Å; Angle (θ) = -57°; Distance to plane (a) = 2.0 Å</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-ethoxy-4-hydroxybenzonitrile is a chemical compound that is found in many plants, such as eucalyptus and lavender. It has been shown to have an attractant effect on Diptera, especially Drosophila dorsalis. The structure of 3-ethoxy-4-hydroxybenzonitrile is similar to that of veratrole and methyl eugenol, both compounds that are known to be chemically attractive to flies. In the laboratory, 3-ethoxy-4-hydroxybenzonitrile has been shown to be more effective than either veratrole or methyl eugenol at attracting Drosophila dorsalis. This chemical can also cause damage when irradiated with ultraviolet light.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Chloromethyl)phenol is a sulfonating agent that can be used as a reagent for the preparation of sulfonic acids, which are important for their use in pharmaceuticals and as dyes. 3-(Chloromethyl)phenol has been shown to react with anions such as chloride and bromide, forming the corresponding sulfonyl chlorides. This reaction is reversible, and the equilibrium constant can be increased by adding more 3-(chloromethyl)phenol or other bases such as carbon disulfide. The thermochemistry of this reaction is enthalpy driven and shows additivity with respect to the concentration of reactants at low concentrations.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>