Building Blocks

<p>2-(Methylamino)-5-nitrobenzoic acid is a benzimidazole that contains a planar, aromatic ring and an amino group in the side chain. The compound is a hydrogen bond donor and acceptor. It undergoes oxidative cyclisations to form benzoic acids from anilines, which are generated through hydrogen atom abstraction. 2-(Methylamino)-5-nitrobenzoic acid also reacts with other aromatic compounds to form dimers or benzoic acids.</p>

5-Chloro-2-phenoxyphenol (5CPP) is a phenolic compound that inhibits bacterial growth by binding to the diphenyl ether binding site on the enzyme fatty acid synthase. 5CPP is an inhibitor of bacterial fatty acid biosynthesis and has been shown to be effective against wild-type strains of staphylococcus aureus, including methicillin resistant strains. 5CPP binds to the active site of the enzyme and prevents it from functioning, thereby inhibiting production of fatty acids. It also has shown activity against Listeria monocytogenes and Bacillus subtilis.

<p>2-Methoxy-2-phenylethan-1-amine is a modification of an amino acid that can be used to synthesize drugs. It belongs to the chemotype phenethylamines, which are compounds that contain a benzene ring and an amine group. 2-Methoxy-2-phenylethan-1-amine has been shown to bind to dopamine D4 receptors in the brain, which may contribute to its psychoactive effects. This compound is also able to inhibit chemokine production, which may help with inflammatory conditions such as asthma.</p>

<p>Samarium(III) isopropoxide (Sm(0)IPO) is a metal ion that has a slow reaction rate with hydrochloric acid in the presence of nitrogen atoms. It can be used to form chiral compounds. Sm(0)IPO, which has fluorescence properties, is used as an analytical reagent in organic chemistry and biochemistry. The reactions of Sm(0)IPO are initiated by the protonation of the hydroxyl group on the metal ion followed by nucleophilic attack by the amino acid serine protease. This reaction results in the formation of an acyl halide.</p>

<p>3-(Dimethylamino)-1-phenylpropan-1-one hydrochloride (3DAPOH) is a potent and selective inhibitor of the enzyme fatty acid synthase. 3DAPOH is used in tissue culture to inhibit the growth of cancer cells. This drug has been shown to inhibit the development of xeno-graft tumors in mice. 3DAPOH also inhibits the growth of Gram-positive bacteria and anthelmintic drugs, such as Fasciola hepatica, Trichostrongylus axei, and Ascaris suum. The mechanism by which this drug inhibits bacterial growth is not well understood; however, it may be due to its ability to induce apoptosis in certain types of cells.</p>

<p>4-Chlorobenzenediazonium is a benzenediazonium salt that can be used to form arylating agents. It has been used in the synthesis of olefins and as a reagent for the synthesis of 4-chloro-3-(4-chlorophenyl)butan-2-one, which is an intermediate for the synthesis of dyes. 4-Chlorobenzenediazonium can also be used to synthesize cyano compounds from nitroarenes and chloroformates.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methyl-2-phenylbutyric acid is a reactive chemical that has a basic group and an ionic character. It is synthesized by the reaction of acetone with methyl iodide in the presence of sodium hydroxide and potassium carbonate. The product can be racemized to its isomer, 2-phenylbutyric acid, by heating with hydrochloric acid or acetic acid. 3-Methyl-2-phenylbutyric acid has been used in chromatographic analysis for the separation of phenols, amino acids, and other compounds. 3-Methyl-2-phenylbutyric acid also reacts with nucleophiles such as water to form ion pairs.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>