Building Blocks

<p>Versatile small molecule scaffold</p>

<p>8-Oxabicyclo[3.2.1]octan-2-one (8OBA) is a β-unsaturated ketone with an oxime group at the 8 position. It can be prepared by cyclization of 2,5-diketones with a phosphonate ester in the presence of a base. The syntheses of various ketones have been accomplished using this process, including β-unsaturated ketones and oxophosphonates. This compound is also used as a building block for synthesis of furan derivatives, such as 2,5-furandione and 3,6-dihydro-4H-pyran.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenylcyclopent-2-en-1-one is a cyclic ketone that can be used in the preparation of 2-phenylcyclopentanones by deoxygenation. The compound can also be converted to cyclopentenones by treatment with alcohols, olefins, or esters. It is also useful for the synthesis of the vinyl ethers and cycloadditions. The reduction of this molecule produces cyclohexanol. Treatment with methanol produces 1,4-benzodiazepine derivatives. Finally, it can be used for annulation reactions as well.</p>

<p>1-Chloro-4-(isocyanomethyl)benzene is a heterocyclic compound that belongs to the morpholine family. It is activated by electron withdrawing groups such as nitro, chloro, and cyano groups. The functionalities of this molecule are amines, nitro, and chloro. 1-Chloro-4-(isocyanomethyl)benzene has been shown to be an inhibitor of pyrrole synthesis in biochemical studies. In addition, it has been shown to be a competitive inhibitor of xanthate oxidation in cyclic biochemical reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-3-iodoprop-1-ene is a synthetic chemical that is used as a reagent in organic synthesis. It has been shown to react with alkyl halides, acyl halides, and anilines to produce β-chloro ketones, α,β-unsaturated esters, and chloroamidines respectively. The reaction with chloride ions produces 2-chloroethyl chloroacetate. This compound can also be used to cross-couple aromatic rings using palladium catalysts. 2-Chloro-3-iodopropane is a precursor to polyphosphoric acid (PPA), which is used in the production of fertilizers.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Butyl-2-cyanoacetamide is a chemical compound that is used to express nature and functionalized. The chemical formula for N-Butyl-2-cyanoacetamide is CH3CONHC(CN)COOCH3. It has a melting point of -80 degrees Celsius, a boiling point of 150 degrees Celsius, and a density of 1.08 grams per cubic centimeter.</p>

<p>2-Cyano-N-methyl-N-phenylacetamide is a diazo compound that is used as a ligand for the β-lactams. It can be prepared by reacting methylcyanamide with phenylacetic acid in the presence of nitrous acid. 2-Cyano-N-methyl-N-phenylacetamide reacts with carbonyl groups to form an oxime, which can be hydrolyzed to produce an amine. This reaction occurs intramolecularly and catalysed by copper or silver salts. The houben–hoesch reaction of 2,4,6,8 tetramethylpiperidine with 2-cyano N -methyl N -phenyl acetamide yields the piperidine derivative 1-(2 cyanoethyl)-2-(2 methoxyethoxy)ethylamine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>