Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>2-Aminothiazolo[5,4-b]pyridine is an isothiocyanate that has potent antiproliferative and anticancer effects. It causes the inhibition of tumor growth by inhibiting the activity of enzymes such as DNA polymerase or topoisomerase II. 2-Aminothiazolo[5,4-b]pyridine also inhibits the proliferation of cancer cells and induces apoptosis. The anticancer effects are due to its ability to inhibit tumor cell growth and induce apoptosis in cancer cells.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Sodium 5-Formyl-2-furansulfonate is a water soluble amine that is used as an additive in the production of pharmaceuticals, agricultural chemicals, and coatings. It is an anticoagulant that has been shown to prevent blood clotting by inhibiting platelet activation. Sodium 5-Formyl-2-furansulfonate can be used as a coating on medical devices and implants to prevent clotting. One of its most promising applications is in the development of new drug delivery systems for drugs with low solubility or poor bioavailability. This chemical may also play a role in the prevention of atherosclerosis by modifying fibrinogen and dopamine, which are important for regulating blood pressure.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Bromo-3-methoxy-1,2-thiazole is a carboxylic acid. It is a cyanating agent and can be used to form carboxamides. The dealkylation of 4-bromo-3-methoxy-1,2-thiazole gives methyl 4-(4′-bromophenyl)butanoate. Halogenation of the carbonyl group leads to the formation of 4-(4′-chlorophenyl)butanoic acid. 4-(4′-Bromophenyl)butanoic acid can be converted into an isothiazole by reacting with potassium hydroxide in methanol.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Ethyl bicyclo[2.2.2]octane-1-carboxylate is a chelate ring that has been shown to enhance the absorption of drugs into the skin and other tissues. It is a cationic surfactant with the ability to form hydrogen bonds in intermolecular and intramolecular configurations. Ethyl bicyclo[2.2.2]octane-1-carboxylate has been used as a catalyst in the synthesis of palladium complexes, as well as an absorption enhancer for hydrophobic compounds such as pesticides, herbicides, and fungicides. The coordination geometry of ethyl bicyclo[2.2.2]octane-1-carboxylate allows it to form hydrogen bonds with nitrogen atoms in proteins and other molecules, which enhances its absorption properties when applied topically on human skin or other tissues.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Benzofuran-5-ylmethanol is an aromatic ether that finds applications in various industries such as research chemicals, medicines, and catalysts. It is used as a building block for the synthesis of compounds like oxalyl glycine, aldehyde dimers, and trifluoroacetic acid. Benzofuran-5-ylmethanol also exhibits antiviral properties and has been studied for its potential in inhibiting viral replication. Additionally, it is a precursor for the synthesis of phenylethylamine derivatives and polyunsaturated fatty acids. With its diverse range of applications, Benzofuran-5-ylmethanol serves as a valuable compound in the field of organic chemistry and industrial processes.</p>

<p>5-hydroxy-4-methoxy-2-nitrobenzoic acid is a synthetic antioxidant that is synthesised from α-tocopherol. It has been shown to be an effective scavenger of hydroxyl radicals and reactive oxygen species, which are involved in the oxidative degradation of biomolecules. 5-Hydroxy-4-methoxy-2-nitrobenzoic acid can be used as an antioxidant in food and cosmetics. This compound also reacts with linoleic acid, forming a phenolic product, which has antioxidant activity.</p>