Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-(3-Fluorophenyl)-1,3,4-thiadiazol-2-amine is a white crystalline solid that is soluble in water. It reacts with hydrogen chloride to form 5-(3-chlorophenyl)-1,3,4-thiadiazol-2-amine and 5-(3-fluorobenzene)-1,3,4-thiadiazol-2-amine. The two dimers are centrosymmetric.</p>

<p>4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol is a fluorescent probe that has been shown to be active against the transcription-polymerase chain of various plant viruses. It is also capable of inhibiting the replication of human immunodeficiency virus type 1 (HIV-1) and murine leukemia virus (MLV). 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol has been used to detect signal in living cells and tissues by fluorescence microscopy. This probe can also be used to detect protein ubiquitination and proteasomal degradation in a variety of organisms, including humans and mice.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Isopropyl 2-pyridyl ketone is an oxime that can be obtained from the reaction of pyridine and acetone. This compound is known for its diastereoselectivity, which is the preference of one stereoisomer over another. Isopropyl 2-pyridyl ketone has been shown to react with ammonium salts to form quaternary salt. The quaternary salt can then react with amines to form optically active products. Isopropyl 2-pyridyl ketone also reacts with hydrocarbons to form cyclic compounds.</p>

<p>1,2-Bis(pyridin-2-yl)ethan-1-one is a ligand that has an enolate form. It is a ferromagnetic compound with a solvothermal synthesis and trinuclear crystal structure. This ligand can be used as a catalyst in organic reactions and as a magnet to study magnetic properties.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-4-[(dimethylcarbamoyl)amino]benzoic acid is an anticancer agent that inhibits the growth of cancer cells by inhibiting the enzyme catalysis that is required for the synthesis of DNA. This drug is a synthetic compound with an active methylene group and an ester hydrochloride group. 2-Chloro-4-[(dimethylcarbamoyl)amino]benzoic acid also has a hydroxy group, which can be activated by enzymes such as enamine to form a reactive methylene, which reacts with other molecules to form reaction products. The mechanism of 2-chloro-4-[(dimethylcarbamoyl)amino]benzoic acid is similar to that of other anticancer drugs such as amine and amide.</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 6-hydroxy-1,3-benzothiazole-2-carboxylate (EHTBC) is a heterocyclic compound that belongs to the class of fluorinated benzothiazoles. It is used in analytical chemistry as a fluorescent probe for detection of ammonium ions. The fluorescence intensity of EHTBC is proportional to the concentration of ammonium ion and can be detected by a spectrophotometer with an excitation wavelength at 360 nm and emission wavelength at 450 nm. The detection time is typically less than 30 seconds. EHTBC has also been shown to have analytical applications in detecting fluoride ion and other halide ions in water samples. Fluoride ions react with EHTBC to form the fluorescent product ethyl 2-[6-(diethylamino)hexyloxy]benzoate, which can be detected by a fluorimeter with an excitation wavelength at 365 nm and emission wavelength at 480 nm.</p>

<p>2,3-Dihydro-1H-indole-1-carboximidamide is a heterocyclic compound that features a 6alkyl, nitro or heteroaromatic ring. It is an intermediate for pharmaceutical formulations and it has been shown to be active against various bacterial strains. 2,3-Dihydro-1H-indole-1-carboximidamide also has nitrogen and halogen atoms, as well as heteroatoms such as oxygen, sulfur and phosphorus. It can have a 6membered or a 5membered ring with one or two heteroatoms.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>