Building Blocks

<p>Versatile small molecule scaffold</p>

<p>1-(Sulfamoylamino)propane is a synthetic sulfonamide with a chemical ionization mass spectrum. It has been shown to inhibit drug-metabolizing enzymes such as cytochrome P450, which may lead to increased levels of the active form of the drug. This compound has been studied for its potential use in Alzheimer's disease and cardiovascular diseases. 1-(Sulfamoylamino)propane also inhibits viral replication and β-amyloid production, and it is an anti-infective agent.</p>

<p>(Ethylsulfamoyl)amine is a drug that can be used as a cancer therapy. It has been shown to inhibit the growth of cancer cells by targeting mitochondrial functions and protein synthesis. The drug also has anti-inflammatory properties and can be used to treat depression, but is not effective in treating bacterial infections. (Ethylsulfamoyl)amine is an amide with sulfamate and sulfamic acid functional groups. It has been shown to have antimicrobial activity against certain bacteria such as Mycobacterium tuberculosis, Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Proteus mirabilis. (Ethylsulfamoyl)amine is also an aliphatic hydrocarbon with heterocyclic properties that can be used as a hypoxic tumor-targeting particle for radiation therapy.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Difluoromethoxy)benzamide is an intermediate in the synthesis of roflumilast, which is a drug used to treat asthma. This intermediate is produced by condensation of methoxybenzoic acid with benzaldehyde and hydrochloric acid. The product can be purified by recrystallization or by conversion to its n-oxide, which has advantages over the chloride form because it is easier to handle and has less impurities. 4-(Difluoromethoxy)benzamide can be used in the industrial production of roflumilast, as it reacts quickly and easily with other chemicals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methyl-2-[(2-methylphenyl)formamido]pentanoic acid is a synthetic compound that inhibits the growth of certain types of bacteria, fungi, and viruses. It is thought to work by disrupting the synthesis of DNA and RNA. 4-Methyl-2-[(2-methylphenyl)formamido]pentanoic acid has not been studied for use in humans. However, it has shown effectiveness against microorganisms such as Escherichia coli, Staphylococcus aureus, Salmonella typhimurium, Listeria monocytogenes, Candida albicans, Trichophyton mentagrophytes, and Saccharomyces cerevisiae.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(1,1-Dioxo-1,2-benzothiazol-3-yl)amino]-4-methylpentanoic acid (PDB code: 2WZH) is a peptide that has been shown to activate the ion channel TRPV4. It has also been shown to be an inhibitor of protein interactions and receptor binding. PDB codes for 2-[(1,1-Dioxo-1,2-benzothiazol-3-yl)amino]-4-methylpentanoic acid are 2WZH and 1J0E.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>