Alcohols

<p>Applications 2-(2-Aminoethylamino)ethanol is a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Its used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013);<br></p>

<p>Applications 1-Phenyl-1,2-propanediol is a reagent in pharmaceutical chemistry, used in the synthesis of nor(pseudo)ephedrine related compounds.<br>References Sehl, T. et al.: Green Chem., 16, 3341 (2014); Moorthy, J. et al.: J. Org. Chem., 76, 9593 (2011);<br></p>

<p>Applications Triphenylsilanethiol is a useful organic building block used for carboxyl activation via silylthioesterification, and in the preparation of synthesis of tetraphenylporphyrinate manganese(III) siloxides.<br>References Lamar, A. A.; et al.: Tetrahedron Lett., 56, 6034 (2015); Meininger, D. J.; et al.: J. Coord. Chem., 69, 1970 (2016).<br></p>

<p>Applications 5,16-Androstadien-3-ol is a useful analyte in the study of stir bar sorptive extraction-​thermal desorption-​capillary GC-​MS applied to biological fluids.<br>References Tienpont, B., et al.: Anal. Bioanal. Chem., 373, 46 (2002);<br></p>

<p>Applications 6-Mercapto-1-hexanolcan be used as a chemical linker for anchoring biological molecules to gold surfaces.<br>References McKinlay, C. J. et al.: J. Am. Chem. Soc 138, 3510 (2016)<br></p>

<p>Applications Glycerol 1-oleyl ether is a surfactant that forms a micellar solution as well as hexagonal liquid crystal phase in solution. It can also be used as a host to grow membrane proteins.<br>References Barauskas, J. et al.: Coll. Surf. B. Biointer., 41, 49 (2005);<br></p>

<p>Applications 2-Ethoxyphenol is used in the studies on the inhibition of oral bacteria by phenolic compounds. Studies on the prostagladins cyclooxygenase inhibition by phenolic compounds. Reagent for the stereoselective preparation of (arylthiomethyl)morpholines as selective norepinephrine reuptake inhibitors and dual serotonin/norepinephrine reuptake inhibitors.<br>References Sharpiro, S., et al.: Quantitative Structure-Activity Relationships, 17, 327 (1998); Dewhirst, F. E., et al.: Prostaglandins, 20, 209 (1980); Boot, J., et al.: Bioorg. Med. Chem. Lett., 15, 699 (2005)<br></p>

<p>Applications 1-Hexanol was examined as a perturbing agent on actomyosin ATPase and and was found to modulate the function of actomyosin motor via intermediate-specific structural perturbation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Komatsu, H., et al.: J. Muscle. Res. Cell. Motil., 25, 77 (2004); Hua, J.F., et al.: J. Insect. Physiol., 59, 690 (2013);<br></p>

<p>Applications 3-Phenoxy-1,2-propanediol (cas# 538-43-2) is a useful research chemical.<br></p>

<p>Applications Heptamethylcyclotetrasiloxan-2-ol is a derivative of Octamethylcyclotetrasiloxane (O237145), which is an organometallic reagent that can be used in the preparation of siloxane polymers, with high surface-hydrophobicity restoration.<br>References Fritz, O., et al.: MRS Online Proceedings Library, 1535 (2012); Vanossi, A., et al.: Condensed Matter (2013);<br></p>

<p>Applications 4-(3’,6’-Dimethyl-3’-heptyl)phenol Diethoxylate (cas# 1119449-38-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-(ethylamino)phenol (cas# 621-31-8) is a useful research chemical.<br></p>

<p>Applications 6-Undecanol (cas# 23708-56-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Cetearyl alcohol (cas# 67762-27-0) is a fatty alcohol which is understood to cause contact dermatitis. Ceteryl alcohol also appears in the preparation of solid lipid nanoparticles, nanostructured lipid carriers and nanoemulsion of lornoxicam for transdermal delivery.<br>References Corazza, M.; et al.: Contact dermatitis, 68, 189 (2013). Gonullu, U.; et al.: Acta Pharmaceutica, 65, 1 (2015).<br></p>

<p>Applications Phenol-OD (CAS# 1003-66-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Thymyloxyethanol is an intermediate in the synthesis of monoterpene compound that has a fresh minty camphor-like odour, and naturally occurs in extracts of commercial oil of peppermint.<br>References Birch, A. J., et al.: J. Chem. Soc., 2531 (1949);<br></p>

<p>Applications 2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino)quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors.<br>References Dudash, J., et al.: Bioorg. Med. Chem. Lett., 21, 4790 (2005); Hellerstein, M., et al.: J. Clin. Invest. 100, 1305 (1994)<br></p>

<p>Applications 5-Aminolevulinic Acid Hydrochloride (cas# CAS:5451-09-2) is a useful research chemical.<br></p>

<p>Applications N-Lauryldiethanolamine (cas# 1541-67-9) is a useful research chemical.<br></p>

<p>Applications Phosphorylethanolamine is used in the synthesis of Sphingomyelin, a type of sphingolipid found in animal cell membrane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Myller, A.T. et al.: Appl. Surf. Sci., 257, 1616 (2010);<br></p>

<p>Applications 5-Ethyl-1,3-benzenediol is a useful compound that is utilized in polycarbonate-​polyester blends. As well, it is a useful reactant for the synthesis of organic compounds such as resorcinol-​formaldehyde, and dihydroxyphthalic acids.<br>References Yurkevichyute, A.S., et al.: Solid Fuel Chem., 50, 64-68 (2016); Chakravarti, S., et al.: U.S.14 pp., Chemical Indexing Equivalent to 148:562759 (WO) Patent 2010 CODEN:USXXAM;<br></p>

<p>Applications (±)-2-Phenylbutanol is used as a reagent in the synthesis of carbamate derivatives of Felbamate (F231000), as potential anticonvulsant agents. (±)-2-Phenylbutanol is also used to prepare analogs of O-(2-phenylethyl)-N-phenylthiocarbamate which can serve as non-nucleoside HIV-1 reverse transcriptase inhibitors.<br>References Kung, C., et al.: Med. Chem. Res., 19, 498 (2010); Cesarini, S., et al.: Bioorg. Med. Chem., 16, 4173 (2008)<br></p>

<p>Applications Diglycerol was used in cosmetic deodorants. It is also a component in thickening and gelatation agents.<br>References Wolf, F., et al.: Eur. Pat. Appl. (1996), EP 691125 A1 19960110.; Yamada, M., et al.: Jpn. Kokai Tokkyo Koho (1980), JP 55025430 A 19800223.<br></p>

<p>Applications 4-Nonylphenol is widely used in manufacturing of polymer stabilizers and nonionic surfactants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Soares, A., et al.: Envir. Inter. 34(7), 1033–049 (2008)<br></p>

<p>Applications N-(Nitrosomethyl)ethanolamine can be used to study the chemical-molecular perspective of the liver specificity of the carcinogenicity of NOCs.<br>References Yuan, J., et.al.: Chem. Res. Toxicol., 25, 2432-2442, (2012);<br></p>

<p>Applications 2,2,4,4-Tetramethyl-1,3-cyclobutanediol (cas# 3010-96-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Ethoxy-1,2-propanediol is a possbile antiknock additive for gasoline and diesel fuel.<br>References Wessendorf, R.: Erdoel &amp; Kohle, Erdgas, Petrochemie, 48, 138 (1995)<br></p>

<p>Applications 2-Octyl-1-tetradecanol is used in preparation of 2-Bromo-2-octyltetradecane (B687015) used in cosmetics formulations.<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Calcifediol is a metabolite of Vitamin D. The principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Morii, et al.: Arch. Biochem. Biophys., 120, 513 (1967); Blunt, et al.: Biochemistry, 7, 3317 (1968), Liu, et al.: Science, 311, 1770 (2006);<br></p>

<p>Applications 9-Fluorenemethanol is used in the design and in the synthesis of novel type somatostatin analogs with antiproliferative activities on A431 tumor cells.<br>References Miyazaki, A., et al.: Tetrahedron Lett., 45, 6323 (2004)<br></p>

<p>Applications 4-Amino-1-pentanol (cas# 927-55-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Phenoxyethanol is a preservative used in cosmetics and is also used as an anesthetic in aquaculture and fisheries.<br>References Pillai, R., et. al.: Cosmet. Technol., 16, 25 (2013); Ghanawi, J., et. al.: Aquac. Res., 44, 359 (2013)<br></p>

<p>Applications 2-(Aminooxy)ethanol<br></p>

<p>Applications 4-tert-Amylphenol, is an antimicrobial pesticide. It has also been shown that para-substituted phenols and their 2-dimethylaminomethyl and 2-phenylthiomethyl derivs. posses antioxidative activity, and is used in lubricating oils, fuels, fats, and polymers.This compound is a contaminant of emerging concern (CECs).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Environmental Protection Agency, Federal Register, 69, 23113 (2004); Abdullaeva, F. A., et al.: Neftekhimiya, 17, 931 (1977);<br></p>

<p>Applications Isopropanol is a volatile organic compound (VOC) that is widely used in the rubber, cosmetics, pharmaceutical, and chemical industries worldwide. Isopropanol’s ability to dissolve a variety of compounds, and its fast evaporation time make it an ideal solvent to work with in the laboratory. Isopropanol is used as a disinfectant in the medical field, and is also utilized for the preservation of biological specimens.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Adams, D., et al.: J. Hosp. Infect., 61, 287 (2005); Bustard, M., et al.: Extremophiles, 6, 319 (2002); Herman, C.: Jour. Lab. &amp; Clin. Med., 26, 1788 (1941)<br></p>

<p>Applications 4-(2-Hydroxyethyl)morpholine is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary culture/DNA.<br>References Conaway, C.C. et al.: Mutat. Res. Gen. Toxicol. Test., 136, 153 (1984); Tsai, S.-W. et al.: Chem. Technol. Biotechnol., 74, 751 (1999);<br></p>

<p>Applications 2-Butoxyethanol is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors.<br>References Sun, Y., et al.: Bioorg. Med. Chem. Lett., 21, 3798 (2011); Yi, W., et al.: Eur. J. Med. Chem., 45, 639 (2010)<br></p>

<p>Applications Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.<br>References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976),<br></p>

<p>Applications 2-Azidoethanol is used as a reagent in the glycosylation of mono- or polysaccharides. 2-Azidoethanol is also used as a 2’-deoxy-ethynyluridine (EdU) blocker in nuclear DNA, preventing cross reactivity with other antibodies in order to better study its related pathways in the body.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liboska, R., et al.: PLOS ONE, 7, e51679 (2012); Sun, X., et al.: Biomacromolecules, 3, 1065 (2002)<br></p>

<p>Applications 1-Pentanol is a volatile component usually found in Jostaberry extracts, and is also used as a reagent to prepare derivatives of Ferulic acid (F308900) and Caffeic acid (C080000) which exhibit anticancer properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hempfling, K., et al.: J. Agr. Food Chem., 61, 9067 (2013); Li, W., et al.: Biorgan. Med. Chem., 22, 6085 (2012)<br></p>

<p>Stability Hygroscopic<br>Applications Diethanolamine similar to triethanolamine (T775580) is used as a surfactant. It also has the potential to be a corrosion inhibitor by means of chemisorption.<br>References Bhajiwala, H.M et al.: Bull. Electrochem., 17, 441 (2001); Yu, J. et al.: Thin. Solid. Films., 379, 7 (2000);<br></p>

<p>Impurity Doxylamine EP Impurity B<br>Stability Light Sensitive<br>Applications Doxylamine intermediate.<br>References Rennison, D., et al.: Bioorg. Med. Chem., 15, 2963 (2007),<br></p>

<p>Applications Sinapyl alcohol (cas# 537-33-7) is a useful research chemical.<br></p>

<p>Stability Unstable in Aqueous Solution<br>Applications 4-Amino-1-butanol is used in the synthesis of NSAIDs with anti-inflammatory properties. Also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Majumder, J. et al.: Langmuir, 29, 10254 (2013); Muth, A. et al.: J. Med. Chem., 56, 5819 (2013)<br></p>

<p>Impurity Betaxolol EP Impurity D<br>Applications 4-[2-(Cyclopropylmethoxy)ethyl]phenol (Betaxolol EP Impurity D) is an intermediate for the synthesis of Betaxolol.<br></p>

<p>Applications (S)-(+)-Propane-1,2-diol is a general reagent used in organic synthesis. (S)-(+)-Propane-1,2-diol is used in the synthesis of anti-tuberculosis agents inspired by BTZ043 for MDR resistant strains.<br>References Tiwari, R. et al.: ACS Med. Chem. Lett., 5, 587 (2014); Tiwari, R. et al.: J. Am. Chem. Soc., 135, 3539 (2013);<br></p>

<p>Applications (Z)-Icos-9-en-1-ol is a useful research chemical for organic synthesis and other chemical processes.<br>References Cheng, J., et al.: Bioresour. Technol., 151, 415 (2014); Marrufo, T., et al.: Molecules, 18, 10989 (2013)<br></p>

<p>Applications 1-Indanol 98% (cas# 6351-10-6) is a useful research chemical.<br></p>

<p>Applications 4-Phenyl-3-buten-2-ol can be used as reagent/reactant for rhodium-catalyzed dynamic kinetic enantio-, chemo- and regioselective allylation of phenols/naphthols/hydroxypyridines with allylic carbonates. It can also be used in biological study for comparative study on quality of soy sauce produced from whole soybeans and defatted soybeans.<br>References Li, C., and Breit, B.: Chemistry- A European Journal, 22, 14655-14663 (2016); Li, X., et al.: Zhongguo Niangzao, 34, 22-26 (2015);<br></p>

<p>Impurity Bisoprolol EP Impurity M<br>Applications 4-[(2-Isopropoxyethoxy)methyl]phenol (Bisoprolol EP Impurity M) is an intermediate for the synthesis of Bisoprolol.<br>References Haeusler, G., et al.: J. Cardiovasc. Pharmacol., 8, S2 (1986), Dubois, E., et al.: J. Med. Chem., 39, 3256 (1996), Horikiri, Y., et al.: J. Pharm. Sci., 86, 560 (1997),<br></p>