Amines

<p>Applications Mono and dibasic phosphate esters are anionic surfactants which have the main feature of the stability in alkaline conditions over other surfactants. They have a wide range of properties including outstanding wetting, emulsification, lubrication, coupling activity and detergency.<br>References Ramirez, F., et al.: Tetrahedron, 35, 1581 (1979);<br></p>

<p>Applications 2-aminobenzenesulfonamide (cas# 3306-62-5) is a useful research chemical.<br></p>

<p>Applications 12-(tert-Butoxycarbonylamino)dodecylamine can be used to synthesize inhibitors of topoisomerase I for use as anticancer agents.<br>References Cinelli, M., et al.:Bioorg. Med. Chem., 17, 7145 (2009); Morrell, A., et al.: J. Med. Chem., 50, 2040 (2007)<br></p>

<p>Applications ethyl 3-aminobutanoate (cas# 5303-65-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Amino(3-​chlorophenyl)​acetic Acid functions as intermediate useful in the preparation of synthetic penicillins, also used in the structure-activity relationship examination of several drugs containing the benzyl moiety, their roles in biochemical and pharmacological processes.<br>References Hansch, C., et al.: J. Med. Chem., 13, 957 (1970); Holdrege, C. T., et al.: Can. (1975), CA 966853 A2 19750429;<br></p>

<p>Applications N-(2-Chloroprop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine is related to the drug Rasagiline(R126030). Rasagiline is used to increase the availability of dopamine at striatal receptors as a method to treat Parkinson’s disease.<br>References Youdim, M.B.H., et al.: Br. J. Pharmacol., 132, 500 (2001); Finberg, J.P., Rambam Maimonides Med. J., 1 (2010)<br></p>

<p>Applications A more base-stable alternative to Ellman’s reagent for the quantification of thiol contents and enzymatic assays under basic pH conditions. . It reacts with free thiols similar to Ellman’s reagent but has dramatically improved stability under alkaline conditions, making it an excellent alternative to Ellman’s reagent.<br>References Zhang, H., et al.: Bioorg. Chem., 26, 356 (1998), Chen, Y., et al.: Biochem., 43, 11491 (2004),<br></p>

<p>Applications Ammonium bisulfite - In water (cas# 10192-30-0) is a useful research chemical.<br></p>

<p>Applications 1-(2-Phenylethynyl)cyclohexanamine is a reactant that functions as a catalyst in the cyclization of propargylamines.<br>References Zhao, D. et al.: ChemCatChem., 9, 4598 (2017); Yuan, R. et al.: J. Org. Chem., 82, 3639 (2017);<br></p>

<p>Applications Aminoacetonitrile is a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.<br>References Ward, Y., et al.: J. Med. Chem., 45, 5471 (2002); Wilkerson, W., et al.: J. Med. Chem., 40, 4079 (1997)<br></p>

<p>Applications hexyl 4-aminobenzoate (cas# 13476-55-6) is a useful research chemical.<br></p>

<p>Applications 9,10-Dihydroergotamine N-Oxide is a useful synthetic compound.<br></p>

<p>Applications (2S)-2-acetamido-5-(diaminomethylideneamino)pentanoic Acid (cas# 155-84-0) is a useful research chemical.<br></p>

<p>Applications 3-Amino-4-hydroxybenzoic acid (cas# 1571-72-8) is a useful research chemical.<br></p>

<p>Applications ethyl 3-amino-3-oxopropanoate (cas# 7597-56-0) is a useful research chemical.<br></p>

<p>Applications N-Benzylethylenediamine can be used to develop imidazoline derivatives as ligands for dopamine D4 receptor. It is also a reagent for enantioselective synthesis of epoxides and piperazinones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mammoli, V., et al.: ChemMedChem 11, 1819 (2016); Meninno, S., et al.: Org. Lett. 17, 4348 (2015)<br></p>

<p>Stability Volatile<br>Applications rac 1,2-Diaminopropane is used as model precursor in the electron induced deposition of amorphous carbon nitride films. It is also used to synthesize cage peroxide, 1,6-diaza-3,4,8,9-tetraoxa-11-methylbicyclo[4.4.2]dodecane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wnuk, J., et al.: J. Phys. Chem., 113, 12345 (2009); Edward, J., et al.: Can. J. Chem., 77, 1057 (1999)<br></p>

<p>Applications 5-Chloropyridazin-3-amine is an intermediate used to prepare aminopyrazines as novel, potent Nav1.7 antagonists.<br>References Bregman, H., et al.: Bioorg. Med. Chem. Lett., 22, 2033 (2012)<br></p>

<p>Applications 2-(4-Aminophenyl)propanoic acid is a reagent in the preparation of 3-aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents (Erratum).<br>References Pevarello, P., et al.: J. Med. Chem., 48, 5058 (2005);<br></p>

<p>Applications 4-Nitro-1,3-diaminobenzene is a general chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of potent and selective Chk-1 inhibitors in the treatment of various cancers.<br>References Wang, L. et al.: J. Med. Chem., 50, 4162 (2007);<br></p>

<p>Applications Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Akesson B. et al.: Int Arch Occup Environ Health. 1986;57(4):297-302. 2. Roos RW. et al.: J Chromatogr. 1986 Dec 24;370(3):403-18.<br></p>

<p>Applications N,N'-Diaminoguanidine Monohydrochloride is an analyte for HPLC. It also functions as an intermediate for the synthesis of energetic salts or materials based on dinitroguanidine.<br>References Shen, K., et al.: Huaxue Gongye Yu Gongcheng Jishu, 35, 74 (2014); Hu, B., et al.: Aust. J. Chem., 67, 1037 (2014); Zhang, Y., et al.: Chem. - A Eur. J., 18, 987 (2012)<br></p>

<p>Stability Light Sensitive<br>Applications A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aslan, K., et al.: J. Fluoresc., 14, 391 (2004), Gole, A., et al.: Langmuir, 20, 7117 (2004), Cavalcante, A., et al.: Biochem. Eng. J., 29, 258 (2006),<br></p>

<p>Applications 1,2,4-Triazin-3-amine can be used as integrade inhibiting antiviral agents.<br>References Kiyama, R., et.al.: PCT Int. Appl.WO 2003016275 A1, 663, (2003);<br></p>

<p>Applications 5-Iodo-2-aminoindane<br></p>

<p>Applications TETRAMETHYLAMMONIUM BOROHYDRIDE (cas# 16883-45-7) is a useful research chemical.<br></p>

<p>Applications 2-{[2-(Dimethylamino)ethyl]methylamino}ethanol is a reagent in the preparation of diamino(aminoalkoxy)quinazolines.<br>References Liu, F., et al.: J. Med. Chem., 53, 5844 (2010);<br></p>

<p>Applications 2-(4-Amino-2-ethoxyphenyl)pthalimide (cas# 106981-52-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-cyclohexylpropan-1-amine (cas# 103254-49-5) is a useful research chemical.<br></p>

<p>Applications 5-(aminomethyl)-2-furoic acid hydrochloride (cas# 934-65-6) is a useful research chemical.<br></p>

<p>Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.<br>References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)<br></p>

<p>Applications N-Ethyl-2,4-dichlorobenzylamine<br></p>

<p>Applications 1,10-Diaminodecane (cas# 646-25-3) is a useful research chemical.<br></p>

<p>Applications 4-(Aminomethyl)-Cyclohexanecarboxylic Acid (cas# 701-54-2) is a useful research chemical.<br></p>

<p>Applications (S)-Pyroglutaminol (cas# 17342-08-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanethiol is used in the preparation of fluorescent N/S acyl derivatives.<br>References 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)thio]ethanamine<br></p>

<p>Applications 4-Azidobutylamine is weakly or non-mutagenic to Salmonella typhimurium.<br>References Owais, W.M., et. al.: Mutat. Res. Genetic Toxicol. Testing, 118, 229 (1983)<br></p>

<p>Applications 2,4-Diaminobenzenesulfonic acid (cas# 88-63-1) is a useful reagent for improving the chlorine resistance and water permeability of polyamide (PA) membrane in water treatment.<br>References Meng, Q. W., et al.: ACS Applied Mat., 12, 35393 (2020)<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 4-(2-Aminophenyl)-4-oxo-2-butenoic Acid is a novel human lens metabolite from normal and cataractous human lenses. A UV filter.<br>References Mizdrak, J., et al.: Tetrahedron, 63, 4990 (2007); Taylor, L. M., et al.: Exp. Eye Res., 75, 165 (2002)<br></p>

<p>Applications Isopropyl 3-Aminocrotonate (cas# 14205-46-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Tetra-N-octylammonium iodide (CAS# 16829-91-7) is a tetraalkylammonium salt and a useful nitrogen-containing building block. Tetra-N-octylammonium iodide is also used as a solid extrantant for platinum and gold in analysis of natural objects.<br>References Dmitriev, S.; et al.: Anal. Sci., 7, 65 (1991).<br></p>

<p>Applications Nonoxidative coloring agent for semipermanent coloring of keratin fibers such as hair and wool.<br>References Chen, C., et al.: Science, 279, 851 (1998), Nitz, M., et al.: Chembiochem., 4, 272 (2003),<br></p>

<p>Applications N-Ethyl-3-phenylpropylamine is an intermediate in the synthesis of 4-Hydroxy Alverine (H827950), a metabolite of Alverine (A575780) in plasma.<br>References Bouvier, M., et al.: Gastroenterol. Clin. Biol., 16, 334 (1992), Mitchell, S., et al.: Aliment. Pharmacol. Ther., 16, 1187 (2002), Hayase, M., et al.: Br. J. Pharmacol., 152, 1228 (2007),<br></p>

<p>Applications 3-Aminohydantoic Acid is an intermediate in the synthesis of new derivative of 5-Nitro-2-furfural, proved to be bactericidal.<br>References Swirska, A., et al.: Rocz. Chem., 31, 1335 (1957);<br></p>

<p>Applications Benzyltrimethylammonium dichloroiodate is used in the mechanism of oxidation.<br>References Srinivasan, N., et al.: Tetrahedron, 30, 419 (1974), Sankhla, R., et al.: J. Chem. Res., 0465 (2002),<br></p>

<p>Applications 5-Amino-2-bromobenzoic acid (cas# 2840-02-0) is a useful research chemical.<br></p>

<p>Applications Used for the preparation of dihydrouracils as anti-ictogenic or anti-epileptogenic agents.<br>References Akoulitchev, S., et al.: Nature, 377, 557 (1995), Marshall, N., et al.: J. Biol. Chem., 270, 12335 (1995), Marshall, N., et al.: J. Biol. Chem., 271, 27176 (1996), Shapiro, G., et al.: J. Clin. Oncol., 24, 1770 (2006),<br></p>

<p>Applications (1R)-2,3-Dihydro-N-2-propen-1-yl-1H-inden-1-amine Ethanedioate is an intermediate used in the synthesis of propargylated aminoindan derivatives via allylation, bromination, dehalogenation sequence.<br>References Phull, M., et al.: PCT Int. Appl., WO 2009081148 A1 20090702 (2009)<br></p>

<p>Applications O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine can be used to treat fibrotic and inflammatory diseases.<br>References Gomer, R.H., et.al., PCT Int. Appl., 167, (2020);<br></p>

<p>Applications Cyclopent-3-enamine hydrochloride (cas# 91469-55-5) is a useful research chemical.<br></p>

<p>Applications trans-4-(Dimethylamino)-3-buten-2-one is an reagent used in the synthetic preparation of various substances.<br>References Maggiulli, C.A., et al.: Org. Prep. Pro. Int., 16, 31 (1984); Afarinkia, K., et al.: Sci. Syn., 14, 275 (2003);<br></p>

<p>Applications [4-(Trimethylammonium)benzyl] Alcohol Bromide is a compound useful in organic synthesis.<br></p>

<p>Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.<br>References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)<br></p>

<p>Applications 4-Aminoindan is a reactant in the preparation of a UBLCP1 proteasome phosphatase inhibitor.<br>References He, Y., et. al.: Bioorg. Med. Chem., 23, 2798 (2015)<br></p>

<p>Applications (3,3-diethoxypropyl)dimethylamine (cas# 16851-30-2) is a useful research chemical.<br>References Choi, G., et al.:Angew. Chem. Int. Ed., 57,6166(2018)<br></p>

<p>Applications 3-DI-N-PROPYLAMINO-1-PROPYNE (cas# 6323-79-1) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br></p>

<p>Applications tert-Butyl 2-Aminobenzoate is a useful reagent for preparing alkylamino quinazolinones.<br>References Lu, C., et al.: J. Org. Chem., 83, 1154 (2018)<br></p>

<p>Applications Tetrabutylammonium Diphenylphosphinate is used as a reagent in the synthesis of the potent antiviral agent (-)-Macrolactin A and its related compounds, (+)-Macrolactin E and (-)-Macrolactinic Acid, via a Stille cross-coupling reaction.<br>References Smith, A.B., et al.: J. Am. Chem. Soc., 120, 3935 (1998)<br></p>

<p>Applications O,O-Dibutyl Phosphorodithioate is an intermediate used to prepare oligodeoxyribonucleoside phosphorodithioates.<br>References Okruszek, A., et al.: J. Org. Chem., 60, 6998 (1995)<br></p>

<p>Applications Tetrabutylammonium tetrafluoroborate (cas# 429-42-5) is a useful research chemical.<br></p>

<p>Applications (Z)-Benzyl (2-Amino-2-(hydroxyimino)ethyl)carbamate is an intermediate used in the synthesis of N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide (H950690), which is a derivative of Raltegravir (R100305), a potent integrase (IN) inhibitor for WT and S217Q PFV IN.<br>References Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)<br></p>

<p>Applications 4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-butanamine is a reactant that is used for the synthesis of various racemic and biotinylation of azamacrocycles.<br>References Krivickas, S.J., et al.: J. Org. Chem. 72, 8280 (2007).<br></p>