Amines

<p>Applications 2-Amino-N-benzylbenzamide can be used for drug discovery and pharmaceutical manufacturing.<br>References Amini-Rentsch, L., et.al., Ind. Eng. Chem. Res., 58, 10164-10171, (2019);<br></p>

<p>Applications 7-Amino-alpha-tetralone<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Tetrabutylammonium Hydroxide is used in biological studies for the detection of counter-anion effect on antimicrobial activity of tetrabutylammonium salts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ingalsbe, M.L., et al.: Bioorg. Med. Chem., 19, 4984 (2009)<br></p>

<p>Applications Ethyl (1S,3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxycyclohexane-1-carboxylate, is a building block used in various chemicla synthesis. It can be used for the preparation of six stereoisomers of diaminocyclohexane carboxamide as key intermediates for synthesis of factor Xa inhibitors.<br>References Wang, X. et al.: Tetrahedron, Vol.73, Iss.11, P1381-1388 (2017);<br></p>

<p>Applications Ethyl 2-(2-Aminothiazol-4-yl)glyoxylate is used in the synthesis of antibacterial compounds. Also used in the synthesis of antiallergic and antiinflammatory agents, as glycolic amide derivatives.<br>References Takasugi, H. et al.: J. Antibio., 36, 846 (1983); Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);<br></p>

<p>Applications 2,5-Bis(aminomethyl)tetrahydrofuran<br></p>

<p>Applications Methyl 4-(Methylamino)picolinate is a pyridinyl building block and a useful synthetic intermediate.<br></p>

<p>Applications 9-(2-(Benzyloxy)ethyl)-2-((2-(benzyloxy)ethyl)amino)-1H-purin-6-(9H)-one is an intermediate used in the synthesis of 9-(2-Hydroxyethyl)guanine (H942035), which is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.<br>References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);<br></p>

<p>Applications 2-Benzylthio-5-amino-1,3,4-thiadiazole is used to study and investigate its antitumor activities against human cervix adenocarcinoma(HeLa), human liver cancer cell(SMMC-7721), human breast cancer cell(MCF-7) and human lung cancer cell(A549) lines that isfurther evaluated by CCK-8 assay.<br>References Zhao, J., et. al., Chem. Res. Chin. Univ.,30, 764-769 (2014)<br></p>

<p>Applications (2R)-2-(dimethylamino)propan-1-ol (cas# 55197-05-2) is a useful research chemical.<br></p>

<p>Applications 4-phenylcyclohexanamine (cas# 19992-45-1) is a useful research chemical.<br></p>

<p>Applications N1,N1,N2,N2-Tetrakis(2-aminoethyl)-1,2-ethanediamine is used in the preparation of strong circularly polarized luminescence of rare earth complexes<br>References Petoud, S. et al.: J. Am. Chem. Soc., 129, 77 (2007); Xu, J., et al.: J. Am. Chem. Soc., 133, 19900 (2011);<br></p>

<p>Applications 5-PHENYL-1,2,4-TRIAZIN-3-AMINE (cas# 942-60-9) is a useful research chemical.<br></p>

<p>Applications 1-(9H-Purin-6-ylamino)propan-2-ol is a reagent used for organic synthesis and also functions as a plant growth regulator.<br>References Gao, Y., et al.: J. Heterocyclic Chem., 53, 579 (2016); Oda, A., et al.: From Faming Zhuanli Shenqing (2016), CN 105503875 A 20160420; Lira, E. P.: J. Org. Chem., 33, 3355 (1968)<br></p>

<p>Applications 5-Iodo-2-aminoindane<br></p>

<p>Applications Methyl 4-amino-2-fluorobenzoate<br></p>

<p>Applications Methyl 2-Aminothioazole-4-carboxylate (cas# 118452-04-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 2-Amino(hydroxyimino)acetate is an intermediate used in the synthesis of N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide (H942278), which is a photolysis product of Metronidazole (M338880), an antibiotic.<br>References Moore, Douglas E., et al.: Radiation Phy. and Chem., 36(4), 547-50 (1990)<br></p>

<p>Applications 3-Amino-2-(formylamino)-3-iminopropanamide is a Temozolomide (T017775) impurity. Temozolomide acts as a imidazotetrazine alkylating agent. An antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997), Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999), Hait, W., et al.: Cancer Res., 69, 1263 (2009),<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications 6-Aminohexanenitrile (cas# 2432-74-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Amino-2-chloroquinazolin-4(1H)-one is a synthetic reagent.<br></p>

<p>Applications: 2-Amino-7,8-dihydro-7,7-dimethyl-4-propyl-5(6H)quinazolinone (cas# 331966-05-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 4'-Dimethylaminophenyl acetylene<br></p>

<p>Applications A reactant used in the preparation of (-)-Amathaspiramide F.<br>References Sakaguchi, K. et al.: Tetrahedron, 65, 10355 (2009); Sakaguchi, K. et al.: Org. Lett., 10, 5449 (2008)<br></p>

<p>Applications 4-​(Dimethyloxidoamino)​butanoic Acid Hydrochloride, is a metabolite of Lauramine Oxide (L178530), which is a frequently used amine oxide surfactant. It is strongly hydrophilic , and it forms normal micelles and normal liquid crystalline phases.<br>References Kocherbitov, v., et al.: J. Molec. Struct.: Theochem., 808, 111 (2007); Kocherbitov, v., et al.: J. Phys. Chem. B., 110 (27), 13649 (2006); Turan, T.S., et al.: Xenobiotica, 11, 447 (1981)<br></p>

<p>Applications 2-(3-Aminopropylamino)ethanol is the hydroxy analogue of WR-1065 (A576820), a metabolite of Amifostine (A576810). Amifostine is an organic thiophosphate that has the ability to protect a broad range of tissues from cytotoxicity (e.g. from chemotherapeutic agents) without inducing an antitumour response. 2-(3-Aminopropylamino)ethanol is also used as an nucleophilic tag in the detection of human butyrylcholinesterase adducts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Antonadou, D., et al.: Int. J. Rad. Oncol. Biol. Phys., 52, 739 (2002); Kemp, G., et al.: J. Clin. Oncol., 14, 2101 (1996)<br></p>

<p>Applications N-(3-(Dimethylamino)propyl)dodecanamide is used in the study of surface chemistry and colloids as a new surfactnt for hydrate anti-agglomeration in hydrocarbon flowlines and seabed oil capture.<br>References Sun, Minwei, Journal of Colloid and Interface Science, 402, 312-319, (2013)<br></p>

<p>Applications Bis(p-aminophenyl) Ether is a reagent used in the preparation of polyimide-silica composite membranes for gas separation techniques. In addition, it is used in the synthesis of polymer films for electrolyte membranes. Dyes and metabolites, Environmental Testing<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lua, A. et al.: React. Funct. Polym., 73 756 (2013); Song, Y. et al.: J. Pow. Souce., 238, 236 (2013); Saito, K. et al.: React. Funct. Polym., 73, 756 (2013);<br></p>

<p>Applications 4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-butanamine is a reactant that is used for the synthesis of various racemic and biotinylation of azamacrocycles.<br>References Krivickas, S.J., et al.: J. Org. Chem. 72, 8280 (2007).<br></p>

<p>Applications Trimethylphenylammonium Iodide (cas# 98-04-4) is a compound useful in organic synthesis.<br>References Dorweiler, J., et al.: Biochem., 42, 14653 (2003),<br></p>

<p>Applications N-Benzoylcarbonylaminoacetamidine Hydrochloride (cas# 50850-19-6) is a compound useful in organic synthesis.<br>References Kitagawa, H., et al.: Bioorg. Med. Chem. Lett., 17, 4982 (2007),<br></p>

<p>Applications (±)-trans-1,2-Diaminocyclohexane is a reagent used in the thyroid receptor agonists for treatment of androgenetic alopecia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Li, J. J., et al.: Bioorg. Med. Chem. Lett., 20, 306 (2010)<br></p>

<p>Applications Used in the synthesis of novel phosphorothioates and phosphorodithioates as cholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Millard, C., et al.: J. Neurochem., 64, 1909 (1995), Nicolet, Y., et al.: J. Biol. Chem., 278, 41141 (2003), Casida, J., et al.: Chem. Res. Toxicol., 17, 983 (2004),<br></p>

<p>Applications 6-Bromohexyltriethylammonium Bromide (cas# 161097-76-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-AMINO-2,2-DIMETHYL-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE (cas# 105807-84-9) is a useful research chemical.<br></p>

<p>Applications 3,4-Diaminobenzenesulfonic Acid is a useful organic synthetic reagent and a sulfonate-aminium zwitterion.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, J., et al.: Acta Crystallogr. B., 66, 3281 (2010)<br></p>

<p>Applications p-Anilinoaniline is an antioxidant that has shown to cause a reduction of NOx emissions from soybean biodiesel powered DI diesel engines but has increased CO and HC emissions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Varatharajan, K., Cheralathan, M.: Fuel Process Technol., 106, 526 (2013)<br></p>

<p>Stability Hygroscopic<br>Applications [3-(3,4-dimethoxyphenyl)propyl](methyl)amine hydrochloride (cas# 83979-31-1) is a useful research chemical.<br></p>

<p>Applications (1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate Oxalate has been used as a reactant for the preparation of oxadiazole compounds containing cyclohexanediamine moiety.<br></p>

<p>Applications N-aminomorpholine-4-carbothioamide (cas# 6499-15-6) is a useful research chemical.<br></p>

<p>Applications Used for induction of nitrilase activity in Arthrobacter. Used as radioprotective agent.<br>References Houseman, A., et al.: Biochem. 32, 4430 (1993),<br></p>

<p>Applications 4-(4-Aminophenoxy)benzonitrile<br></p>

<p>Applications O,O-Dibutyl Phosphorodithioate is an intermediate used to prepare oligodeoxyribonucleoside phosphorodithioates.<br>References Okruszek, A., et al.: J. Org. Chem., 60, 6998 (1995)<br></p>

<p>Stability Light Sensitive<br>Applications A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aslan, K., et al.: J. Fluoresc., 14, 391 (2004), Gole, A., et al.: Langmuir, 20, 7117 (2004), Cavalcante, A., et al.: Biochem. Eng. J., 29, 258 (2006),<br></p>

<p>Applications 2-Aminomethyl-1,4-benzodioxane is used in the synthesis of N-substituted (dihydrobenzodioxinyl)methylamine derivatives as D2 antagonists/5-HT1A partial agonists with potential as atypical antipsychotic agents in relation to affinity for α1 adrenoceptors.<br>References Birch, A. M., et al.: J. Med. Chem., 42, 3342 (1999);<br></p>

<p>Applications 2-cyclohexylpropan-1-amine (cas# 103254-49-5) is a useful research chemical.<br></p>

<p>Applications TERT-BUTYL N-(DIAMINOMETHYLIDENE)CARBAMATE (cas# 219511-71-4) is a useful research chemical.<br></p>

<p>Applications 4,4-Diethoxy-N,N-diethyl-1-butanamine is a useful reagent for the synthesis of amino acetals.<br>References Keglevic, D., et al.: Croat. Chem. Acta, 35, 175(1963)<br></p>

<p>Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.<br>References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)<br></p>

<p>Applications 5-Amino-2-chlorobenzenesulfonamide (cas# 2015-19-2) is a compound useful in organic synthesis.<br>References Somers, F., et al.: Pharm. Pharmacol. Commun., 6, 89 (2000), D'Ambrosio, K., et al.: J. Med. Chem., 51, 3230 (2008),<br></p>

<p>Applications Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Akesson B. et al.: Int Arch Occup Environ Health. 1986;57(4):297-302. 2. Roos RW. et al.: J Chromatogr. 1986 Dec 24;370(3):403-18.<br></p>

<p>Applications ETHYL 4-AMINO-2-FLUOROBENZOATE (cas# 73792-06-0) is a useful research chemical.<br></p>

<p>Applications ethyl 2-(methylamino)-2-oxoacetate (cas# 18522-95-7) is a useful research chemical.<br></p>

<p>Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.<br></p>

<p>Applications 5-Chloropyridazin-3-amine is an intermediate used to prepare aminopyrazines as novel, potent Nav1.7 antagonists.<br>References Bregman, H., et al.: Bioorg. Med. Chem. Lett., 22, 2033 (2012)<br></p>

<p>Applications 4-Azidobutylamine is weakly or non-mutagenic to Salmonella typhimurium.<br>References Owais, W.M., et. al.: Mutat. Res. Genetic Toxicol. Testing, 118, 229 (1983)<br></p>

<p>Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.<br>References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)<br></p>

<p>Stability Volatile<br>Applications rac 1,2-Diaminopropane is used as model precursor in the electron induced deposition of amorphous carbon nitride films. It is also used to synthesize cage peroxide, 1,6-diaza-3,4,8,9-tetraoxa-11-methylbicyclo[4.4.2]dodecane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wnuk, J., et al.: J. Phys. Chem., 113, 12345 (2009); Edward, J., et al.: Can. J. Chem., 77, 1057 (1999)<br></p>