Amines

<p>3-Amino-2-methoxy-dibenzofuran (3AMD) is a cytotoxic agent that is used in the treatment of bladder carcinoma. 3AMD inhibits DNA synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. 3AMD has been shown to be a potent inhibitor of cyclen-dependent kinases and to induce DNA damage in human cells. 3AMD also has significant cytotoxicity against malignant cells and has been shown to inhibit the growth of tumours in mice. 3AMD may have carcinogenic potential due to its structural similarity with other carcinogens such as aniline and aminobiphenyl.</p>

<p>Please enquire for more information about 1-Fluoro-3-phenylpropan-2-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>DDAVP is an analogue of vasopressin, which belongs to the class of inositol phosphates. It is a potent agonist for the V1 receptor and has a higher affinity for this receptor than vasopressin. DDAVP also has antagonist properties at the V2 receptor. The biological activity of DDAVP is mediated by its ability to increase phospholipase A2 activity and cause the release of arachidonic acid from membrane phospholipids. This activation causes an increase in prostaglandin synthesis, leading to increased vascular permeability and hypotension. DDAVP may also have antidiuretic effects due to its antagonism of oxytocin receptors.</p>

<p>1,3-Bis(dimethylamino)-2-propanol is a polymeric compound that is soluble in water and organic solvents. It has been shown to have a viscosity of less than 2.0 centipoise (cP) at 20°C and pH 8.5. This compound also has a high solubility in buffers, carboxylates, and chloride ions. 1,3-Bis(dimethylamino)-2-propanol has been used as an additive for silicone surfactants and in the production of tetranuclear gold nanoparticles for use in chemiluminescence applications.</p>

<p>2-Thien-2-ylethanamine is an ethylene diamine that inhibits the production of hydrochloric acid. It has been shown to have potent antitumor activity and inhibitory effects on infectious diseases, such as malaria, caused by Plasmodium falciparum. 2-Thien-2-ylethanamine has also been shown to be a mitochondrial membrane potential inhibitor. These properties may be due to its ability to inhibit the action of malonic acid and other molecules that are involved in mitochondrial function. The inhibition of polycystic ovarian syndrome (PCOS) is also thought to be related to the inhibition of mitochondrial function.</p>

<p>Fmoc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid is a pharmacokinetic drug that is under investigation for prostate cancer. It has been shown to inhibit the growth of prostate carcinoma cells and reduce the expression of prostate specific antigen (PSA) in vivo. Fmoc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid has also been used in bioconjugate chemistry to produce a prodrug that can be taken orally. This prodrug is activated by viral proteases in the stomach, leading to an increase in cytotoxicity against HIV virus and other retroviruses. Fmoc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid has also been shown to inhibit the production of human serum erythropoietin (EPO).</p>

<p>Please enquire for more information about 3-Amino-2-bromo-6-chloropyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Boc-1,2-phenyldiamine is a histone acetyltransferase (HAT) inhibitor. It is an acetylated molecule that contains two phenyl rings, one of which is substituted with an amine group. This compound was designed to inhibit the activity of HATs, which are enzymes involved in the chemical modification of histones and other proteins. N-Boc-1,2-phenyldiamine inhibits the activities of these enzymes and prevents the acetylation of lysines on histones or other proteins. It has been shown to be efficient in inducing apoptosis in human cancer cells and may also have some antitumor effects.</p>

<p>Please enquire for more information about DABCYL-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675)-EDANS ammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>2-Amino-3,5-dibromobenzonitrile is an electrophile that is used to synthesize various boronic acid derivatives. It also inhibits butyrylcholinesterase and 2-aminobenzonitrile, enhancing the activity of organophosphorus cholinesterase inhibitors. 2-Amino-3,5-dibromobenzonitrile has been shown to react with nucleophiles at the alpha position to form a stable intermediate. This reaction has been shown to be reversible in aqueous solution. The compound has been evaluated as a potential chemotherapeutic agent against cancer cells in vitro.</p>

<p>4-Aminobutyrophenone is a butyrophenone, a nitro compound that is the amine derivative of 4-aminobutyric acid. This product is used as a control agent in pest control and as an intermediate for pharmaceuticals and dyes. It has been used to produce methemoglobin, which is used to treat nitrate poisoning. 4-Aminobutyrophenone undergoes acylation reactions with chloride or sulfoxide groups to form chlorohydrins and thiohydrins respectively. These products are bioisosteres of the carbonyl group, which can be hydrolyzed with acid or alkali to produce carboxylic acids or alcohols respectively. Friedel-Crafts acylation with phenol gives benzoylphenylhydroxylamine, which can be oxidized by hydrogen peroxide to give the corresponding nitro compound.</p>

<p>3-Amino-4-methylthiophen-2-carboxylic acid methyl ester (3AMTC) is a novel compound that has been shown to have antihypertensive activity, as well as other pharmacological actions. 3AMTC is an allosteric modulator of α7 nicotinic acetylcholine receptors, which are found in the central and peripheral nervous system. The efficacy of 3AMTC was evaluated using magnetic resonance spectroscopy to measure the effects on mouse tumor cells. This compound showed no carcinogenic potential, which may be due to its inability to cross the blood brain barrier.</p>

<p>(R)-1-Boc-3-Aminopyrrolidine is a small molecule that inhibits 3-kinase. It has been shown to bind to the ATP binding site of PI3Kδ and inhibit its activity. This results in the inhibition of phosphoinositide production, which leads to decreased cell proliferation and survival. (R)-1-Boc-3-Aminopyrrolidine has also been shown to have selectivity for isoform α over β, γ, and δ. The drug binds specifically to the ATP binding site on PI3Kδ, but does not disrupt other interactions such as hydrogen bonding or pi stacking interactions with residues in the vicinity of the ATP binding site. The IC50 values for (R)-1-Boc-3-Aminopyrrolidine were determined using siRNA knockdown experiments against human isoform α PI3Kδ.</p>

<p>2-Amino-2-oxoethoxy)acetic acid is a product that can be used as a transport agent in the process of extracting glycosides. It has been shown to have strong adsorption properties and is able to extract glycosides from plant material. 2-Amino-2-oxoethoxy)acetic acid has a high affinity for calcium, which is an important component in the adsorption mechanism.</p>

<p>N-1-Z-1,4-diaminobutane·HCl is a monomeric compound that inhibits protein–protein interactions. It is a broad-spectrum inhibitor of protein–protein interactions and has been shown to have the potential for use in cancer treatments. The linkers on the N-1 and Z positions are important for the interaction with the target protein. The heterocycle at position 1 can vary depending on which protein is targeted. This compound has been effective against a number of proteins that interact with each other, including cyclin A/CDK2, cyclin B/CDK2, and actin/myosin II. This analog has been shown to be achievable by linking two molecules together through an amide bond.</p>

<p>5-Amino-2-methoxy-4-methylpyridine is a small molecule that inhibits bromodomains. Bromodomains are protein domains that bind to acetylated lysine residues on histones. 5-Amino-2-methoxy-4-methylpyridine binds to the bromodomain, preventing the acetylated lysine residues from binding with other proteins and inhibiting transcription. This drug has been shown to be effective in treating prostate cancer by interacting with the androgen receptor. 5-Amino-2-methoxy-4-methylpyridine also interacts with ATPase, which may lead to increased levels of ATP production, and has been shown to have antitumor effects in vitro.</p>