Amines

<p>Impurity Acetazolamide EP Impurity G<br>Applications 5-Amino-1,3,4-thiadiazole-2-thiol is a thiadiazole derivative with antibacterial acitivity used in the preparation of herbicides as well as carbonic anhydrase inhibitors. (Acetazolamide EP Impurity G)<br>References Li, Z. et al.: Ying. Huax., 5, 54 (1988); Supuran, C. et al.: Rev. Roum. Chim., 40, 1227 (1995);<br></p>

<p>Impurity Niltazoxanide USP Related Compound A 2-Amino-5-nitrothiazole<br>Applications Niltazoxanide USP Related Compound A 2-Amino-5-nitrothiazole.<br>References Kariduraganavar, M. et al.; J. Mol. Struct. 987, 158 (2011). Tambe, S. J. et al.; Appl Polymer Sci. 114, 2291 (2009)<br></p>

<p>Applications PROP-2-EN-1-AMINE HCL (cas# 10017-11-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Majority of 1,6-Diaminohexane is used in the manufacturing of Nylon.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chen, G., et al.: Polymer, 47, 4760 (2006); Klitgaard, S., et al.: Green Chem., 10, 419 (2008)<br></p>

<p>Applications 1-aminoindan (cas# 34698-41-4) is a useful research chemical.<br></p>

<p>Applications Ammonium Nonanoate is the salt form of n-Nonanoic Acid (N649385), which is commonly used in conjunction with glyphosate, a non-selective herbicide, for a quick burn-down effect in the control of weeds in turfgrass. It is also used in the preparation of plasticizers and lacquers.<br>References Pline, W., et al.: Weed Technol., 14, 667 (2000); Frade, J., et al.: Anal. Bioanal. Chem., 395, 2167 (2009);<br></p>

<p>Applications Bis(p-acetylaminophenyl) Ether is a chemical reagent used in the synthesis of photosensitive polymer compounds and optical application. It also is used in the preparation of benzimidazole derivatives displaying anti-tumor activity through apoptosis.<br>References Wang, X. et al.: Bioorg. Med. Chem. Lett., 22, 6297 (2012); Gubbelmans, E. et al.: Polymer, 46, 1784 (2005); MacDonald, S. et al.: ACS Symp. Ser., 184, 73 (1982);<br></p>

<p>Applications 6-Aminobenzothiazole is a useful intermediate in synthesizing N-phenyl-substituted and di-substituted guanidinyl benzothiazole derivatives. These derivatives act as antimicrobial and antioxidant agents.<br>References Mahesh, B., et al.: Res. Chem. Intermed., 42, 6195 (2016)<br></p>

<p>Applications N,N-Dimethyltetradecylamine (cas# 112-75-4) is a compound useful in organic synthesis.<br></p>

<p>Applications (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.<br>References Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)<br></p>

<p>Applications 6-Amino-5-1,3-dimethyl-5-(formamido)uracil is a substitued uracilic metabolite of methylxanthine and is also a metabolite of Theophylline (T343850). 6-Amino-5-1,3-dimethyl-5-(formamido)uracil has been used for the synthesis of 8-arylaminotheophyllines.<br>References Peri, G., et. al.: Toxicol. Lett., 18, 133 (1983); Celardo, A., et. al.: Eur. J. Drug Metab. Ph., 10, 279 (1985); Senga, K., et. al.: J. Heterocyclic Chem., 15, 641 (1978)<br></p>

<p>Applications N-[(4-chlorophenyl)methyl]cyclopentanamine is a useful reagent for the preparation of γ-​lactams.<br>References Fujii, T., et al.: Tetrahedron Letters, 61, 152276 (2020)<br></p>

<p>Applications [4-[[4-(dimethylamino)phenyl]-(4-dimethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]phenyl]-trimethylazanium;dichloride (cas# 82-94-0) is a useful research chemical.<br></p>

<p>Applications 4-Aminoantipyrine (cas# CAS:83-07-8) is a useful research chemical.<br></p>

<p>Applications 4-Chlorophenylamine is an organic chemical reagent and precursor in the synthesis of various drugs and dyestuffs. It is a building block and a degredation product of Chlorhexidine (C335045), an antiseptic as well as azo dyes and pigments in printing and textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leucea, D. et al.: Ind. Text., 61, 304 (2010); Below, H. et al.: Microchim. Acta 146, 129 (2004);<br></p>

<p>Applications N-(2-PROPYNYL)-2,3-DIHYDROINDEN-1-AMINE (cas# 1875-50-9) is a useful research chemical.<br></p>

<p>Applications 4-Amino-nicotinonitrile<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.<br>References Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000); Fujita, H. et al.: Brain Res., 1113, 10 (2006); Breese, G.R. et al.: 174, 313 (1970);<br></p>

<p>Applications 9-(2-Chloro-ethyl)-9H-purin-6-ylamine (cas# 19255-48-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Amino-4,6,7,8-tetrahydro-5-(N-carbethoxy)thiazolo[5,4-d]azepine (cas# 887352-60-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-aminobenzene-1,4-disulfonic acid (cas# 98-44-2) is a useful research chemical.<br></p>

<p>Applications 2,​4-​Diaminoanisole is a component and degredation product of azo dyes in fabrics and textiles. Azo dyes occasionally produce carcinogenic effects and environmental reproductive toxicology. Dyes and metabolites, Environmental TestingEnvironmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nguyen, A. et al.: J. Env. Sci. Health A., 51, 744 (2016);<br></p>

<p>Applications 1-Aminopyrene is used in the synthesis of novel fluorescent nanoscale ionic silicate platelets for use in bacterial detection and other biosensor applications.<br>References Lin, H.. et al.: ACS App. Mater. Inter., 7, 10771 (2015);<br></p>

<p>Applications 2-(Acetylamino)-N-(phenylmethyl)propanamide, has shown to have anticonvulsant activity in vitro. Likely an impurity in the medication Lacosamide, (L098500).<br>References Martinez, J C. et al: MATCH, Vol. 67, issue 3, P: 745-758 (2012);<br></p>

<p>Applications Benzyltrimethylammonium Hydroxide is a reagent used in the preparation of dithiocabamates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zaidi, S. et al.: Chem. Biol. Interface., 7, 166 (2017);<br></p>

<p>Applications p-Aminophenyl Arsenoxide is a useful reagent for the study of 2-oxoacid dehydrogenase multienzyme complexes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stevenson, et al.: Biochemistry, 17, 11, 2191 (1978)<br></p>

<p>Applications Tetrabutylammonium Chloride is used in the preparation of polypyrrole coatings with self healing properties for iron corrosion.<br>References Nakayama, M. et al.: Electrochem. Comm., 9, 1145 (2007);<br></p>

<p>Applications 1,3-Diethyl-6-aminouracil (cas# 41740-15-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Trihexylamine is a chemical reagent used i the preparation of infrared luminescence nanohybrid films as well as the isolation and purification of biosuccinic acid used in the pharmaceutical industry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shimizu, T. et al.: Mater. Lett., 110, 180 (2013); Kurzrock, T. et al.: Biotech. Prog., 27, 1623 (2011);<br></p>

<p>Applications 3,3′-Diaminobenzidine is a peroxidase substrate and a reagent for spectrophotometric determination of selenium.<br></p>

<p>Stability Hygroscopic<br>Applications Ammonium oxalate is used as an analytical reagent and general reducing agent. It is commonly employed in soil chemical analysis to extract iron and aluminum from poorly-crystal line minerals.<br>References Seyed, D., et al.: J. Photo. Chem., 394, 112486 (2020); Blanchard, F., et al.: Cryst. Growth Des., 18, 4593-4601 (2018)<br></p>

<p>Applications 2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.<br>References Lacotte, P. et al.: ChemMedChem, 8, 104 (2013); Klein, J. et al.: Org. Lett., 14, 330 (2012);<br></p>

<p>Applications Methyl 5-Aminopentanoate Hydrochloride is used as a reactant to synthesize several compounds with therapeutic potential.<br>References Larson, Peter, et al.: ACS Med. Chem. Let, 8(11), 1148-1152 (2017);Li, Yongtao, et al.: J. of Med. Chem., 61(7), 3166-3192 (2018);Lu, Yuzhi, et al.: ACS Med. Chem. Let., 7(12), 1185-1190 (2016)<br></p>

<p>Applications Triethylamine Trihydrofluoride is used in the synthesis of modified siRNA’s in vivo used to inhibit hepatitis B replication (1). Used in RNA synthesis in the removal of t-butyldimethylsilyl protection (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Marimani M. et al.: Bioorg Med Chem. 2013 Oct 15;21(20):6145-55. 2. Westman, E. et al.: Nucleic Acids Res. 1994 Jun 25;22(12):2430-1<br></p>

<p>Applications 6-Phenylhexylamine Hydrochloride (cas# 120375-57-7) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications Used in the manufacturing of L-tryptophan by enzymic reaction.<br>References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),<br></p>

<p>Applications 2,6-Diaminopimelic Acid is useful in biological studies involving amino acids and amino sugars as molecular indicators of the origins of organic matter in buried tephra soils.<br>References Hobara, S., et al.: Geoderma, 373, 114449 (2020)<br></p>

<p>Applications Tetramethylammonium Triacetoxyborohydride is used in the synthesis of Peloruside A. Epoxypropanoate is a neurokinin substance P receptor antagonist synthesized from this compound.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gazaille, J. et al.: Org. Lett., 14, 178 (2012); Prevost, S. et al.: Tetrahedron Asymm., 21, 16 (2010);<br></p>

<p>Applications Hydrochloride salt of benzyltriethylammonium which acts as a phase-transfer catalyst in chemical reactions.<br>References Shi, Z. et al.: Chem. Sci., 4, 829 (2013); Landeros, J. et al.: J. Mol. Struct., 1037, 412 (2013);<br></p>

<p>Applications Phenyl(9H-purin-6-yl)amine (cas# 1210-66-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(2-Aminoethoxy)anisole is used as an additive to vinylphosphonic acid esters and acrylonitrile forming compounds displaying hypotensive activity. An impurity from the process of Carvedilol (C184625)<br>References Reznik, V. et al.: Russ. Chem. Bull., 48, 979, (1999); Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990), Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996),<br></p>

<p>Applications 2-(4-Diethylamino-2-hydroxybenzoyl)benzoic Acid<br></p>

<p>Applications Diisopropanolamine is used as a reagent in the synthesis of pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors.<br>References Kravchenko, D., et al.: Lett. Drug Des. Discov., 3, 61 (2006)<br></p>

<p>Impurity Brimonidine EP Impurity C<br>Applications 6-Quinoxalinamine is used in the synthetic preparation and evaluation of novel nitroheterocyclic hypoxic markers for solid tumor.<br>References Zhu, W., et al.: Bioorg. Med. Chem., 16, 3255 (2008)<br></p>

<p>Applications N,N-Dicyclohexylmethylamine is used as a reagent in the base preparation of 13C2- and 2H phenethylamines as internal standards for IDMS by Pd-catalyzed double carbonylation of aryl iodides in the presence of amine nucleophiles followed by deoxygenation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nielsen, D., J. Org. Chem., 74, 6155 (2012)<br></p>

<p>Applications Triphenylamine (cas# 603-34-9) is a useful research chemical.<br></p>

<p>Applications (S)-2-Amino-4-[(3-aminopropyl)amino]-butanoic Acid is used in the reaction of carboxynorspermidine decarboxylase of Vibrio alginolyticus.<br>References Nakao, H., et al.: J. Gen. Microbiol. 136, 1699-704 (1990)<br></p>