Amines

<p>Applications Sulfur Trioxide Triethylamine Complex is a reagent used for the sulfation of polysaccarides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Papy-Garcia, D., et al.: Macromol., 38, 4647 (2005); Langston, S., et al.: Helvetica Chimica Acta, 77, 2341 (1994)<br></p>

<p>Applications 1-Phenyl-2-butanamine (cas# 30543-88-5) is a useful research chemical.<br></p>

<p>Applications Triethylamine Trihydrofluoride is used in the synthesis of modified siRNA’s in vivo used to inhibit hepatitis B replication (1). Used in RNA synthesis in the removal of t-butyldimethylsilyl protection (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Marimani M. et al.: Bioorg Med Chem. 2013 Oct 15;21(20):6145-55. 2. Westman, E. et al.: Nucleic Acids Res. 1994 Jun 25;22(12):2430-1<br></p>

<p>Applications 2-(2-Aminoethylamino)ethanol is a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Its used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013);<br></p>

<p>Applications Trihexylamine is a chemical reagent used i the preparation of infrared luminescence nanohybrid films as well as the isolation and purification of biosuccinic acid used in the pharmaceutical industry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shimizu, T. et al.: Mater. Lett., 110, 180 (2013); Kurzrock, T. et al.: Biotech. Prog., 27, 1623 (2011);<br></p>

<p>Applications 4-AMINOPYRENE (cas# 17075-03-5) is a useful research chemical.<br></p>

<p>Applications 2-Amino-2,3-dimethylbutyramide is an important intermediate in the synthesis of potent imadazoline herbicides. In addition, it is used to prepare new chiral ligands.<br>References Lin, Z. et al.: J. Ind. Microbiol. Biotech., 39, 133 (2012); Lin, Z. et al.: Biotech. Lett., 33, 1809 (2011); Sedlak, M. et al.: Tetra. Lett., 45, 7723 (2004);<br></p>

<p>Applications 4-Amino-6-(tert-butyl)-3-mercapto-4,5-dihydro-1,2,4-triazin-5-one (cas# 33509-43-2) is a useful research chemical.<br></p>

<p>Applications E-3-(Tributylstannyl)-2-propen-1-amine (cas# 202115-92-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Impurity Mesalazine EP Impurity C<br>Applications 2-Aminophenol is an isomer of 4-Aminophenol (A618920) and is used as a reagent for the synthesis of heterocyclic compounds and dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pan, E., et al.: Chem. Sci., 4, 482 (2013); Meek, A.R., et al.: Can. J. Chem., 90, 865 (2012); Kiorpelidous, E., et al.: Chem. Res. Toxicol., 25, 2054 (2012);<br></p>

<p>Applications 2-Amino-4,6,7,8-tetrahydro-5-(N-carbethoxy)thiazolo[5,4-d]azepine (cas# 887352-60-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Amino-2-propanol is a reagent used in the synthesis of protein kinase CK2 inhibitors used in the treatment of neoplasia and other infective diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pagano, M. et al.: J. Med. Chem., 47, 6239 (2004);<br></p>

<p>Applications 6-Aminobenzothiazole is a useful intermediate in synthesizing N-phenyl-substituted and di-substituted guanidinyl benzothiazole derivatives. These derivatives act as antimicrobial and antioxidant agents.<br>References Mahesh, B., et al.: Res. Chem. Intermed., 42, 6195 (2016)<br></p>

<p>Applications Tributylamine is used as a reagent in the syntheses of quaternary ammonium-containing trithiocarbonate RAFT agents and hemi-telechelic cationomers. Tributylamine is also used as a corrosion inhibitor for mild steel in hydrochloric acid and as an initiator for cracking of heptane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, L., et al.: Polymer Chem., 5, 1180 (2014); Bastidas, J.M., et al.: J. Mater. Sci., 35, 2637 (2000); Wang, Z., et al.: Energ. Conver. Manage., 49, 1584 (2008)<br></p>

<p>Stability Hygroscopic<br>Applications N-​Ethyl-​α-​methyl-​3-​(trifluoromethyl)​-benzeneethanamine hydrochloride has been used in case studies for the study of impulsivity, motor skills, and anxiogenic effects in the neuroscience community.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Whitney, K.N., et al.: Exp. Clin. Psychopharm., 21, 345-54 (2013); Arrant, A.E., et al.: Neuropharmacology, 65, 213-22 (2013)<br></p>

<p>Applications A reagent used for the synthesis of hydroxylamines and hydroxyamates.<br>References Magin, D.F., et al.: J. Chromatogr., 178, 219 (1979), Safavy, A., et al.: Bioconjug. Chem., 13, 327 (2002),<br></p>

<p>Stability Hygroscopic<br>Applications 4-(2-Aminoethyl)benzene-1,2-diol has been studied for its role in Parkinson's disease.<br>References Segura-Aguilar, J.: Neural Regeneration Research, 12, 897 (2017)<br></p>

<p>Applications N-(5-Aminopentyl)acetamide is an acetylated polyamine, a promising biochemical marker for cancer and many other pathophysiological conditions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hakkinen, M. R., et al.: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci., 941, 81 (2013); Paik, M., et al.: Clin. Chim. Acta, 411, 1532 (2010)<br></p>

<p>Applications N-Ethyl-N-(2-hydroxyethyl)nitrosamine is a member of the nitrosamine class of carcinogens and induces renal cancer. It has been shown to induce tumors in the kidneys of rats and in the lungs of mice.<br>References Hiasa, Y., et al.: Cancer Lett, 145, 143-149 (1999)<br></p>

<p>Impurity Acetazolamide EP Impurity G<br>Applications 5-Amino-1,3,4-thiadiazole-2-thiol is a thiadiazole derivative with antibacterial acitivity used in the preparation of herbicides as well as carbonic anhydrase inhibitors. (Acetazolamide EP Impurity G)<br>References Li, Z. et al.: Ying. Huax., 5, 54 (1988); Supuran, C. et al.: Rev. Roum. Chim., 40, 1227 (1995);<br></p>

<p>Applications 2-(3,4-Diethoxyphenyl)ethanamine is a useful intermediate in the preparation of Drotaverine hydrochloride, an antispasmodic drug arising from papaverine class of biologically active compounds.<br>References Turks, M., et al.: Rigas Tehniskas Universitates Zinatniskie Raksti, Serija 1: Materialzinatne un Lietiska Kimija, 23, 107 (2011)<br></p>

<p>Applications 4-Amino-3-hydroxybenzoic Acid is disubsituted benzoic acid used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors.<br>References Kono, K. et al.: J. Antibiot., 53, 759 (2000);<br></p>

<p>Applications Triethanolamine is used primarily as a surfactant, reducing the surface tension between two media. It is also used as a general emulsifier for preparations, such as ones involving drug penetration assays.<br>References Huo, Q. et al.: Chem. Mat., 8, 1147 (1996); Alves, MN. et al.: Int. J. Pharm., 341, 215 (2007);<br></p>

<p>Applications O-Benzylhydroxylamine (cas# 622-33-3) is a useful research chemical.<br></p>

<p>Applications 5-Amino-1-pentanol is an aliphatic amino alcohol with potential plasma lipid-lowering properties. 5-Amino-1-pentanol and other amino alcohols are used as emulsifying agents in dry-cleaning soaps, wax removers, cosmetics, paints and insecticides.<br>References Bondesson, G. et al.: Acta Pharm. Suec., 11, 417 (1974); Scheers, E.M. et al.: ALTA Alt. Lab. Anim., 30,309 (2002);<br></p>

<p>Applications Dimethyl Aminoterephthalate is used to prepare imidazotetrazinones as probes for action of temozolomide. It can be used to prepare aminoquinazolines with neurokinin-2 receptor antagonist activity.<br>References Clark, A., et al.: J. Med. Chem., 38, 1493 (1995); Jacobs, R., et al.: Bioorg. Med. Chem. Lett., 5, 2879 (1995)<br></p>

<p>Stability Unstable in Aqueous Solution<br>Applications 4-Amino-1-butanol is used in the synthesis of NSAIDs with anti-inflammatory properties. Also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Majumder, J. et al.: Langmuir, 29, 10254 (2013); Muth, A. et al.: J. Med. Chem., 56, 5819 (2013)<br></p>

<p>DEAC, SE (7-Diethylaminocoumarin-3-carboxy acid) is a blue fluorescent dye for labeling amine-containing organisms. λex of DEAC, SE is 330 nm and λem is 402</p>

<p>Applications 1,3-Diaminopropane is a common chemical reagent, used in the synthesis of 7-methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors applied in the treatment of Alzheimer’s disease. Also used in the synthesis of thrombosis inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Spilovska, K. et al.: Molecules, 18, 2397 (2013); Smith, S. et al.: Blood, 120, 5103 (2012);<br></p>

<p>Applications N,N-Dimethyldodecylamine is used as a reagent in the synthesis of epoxy quaternary ammonium salt surfactants which exhibit potential antibacterial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, Y., et al.: J. Disper. Sci. Technol., 35, 1460 (2014)<br></p>

<p>Applications Ethanolamine is used in the preparation of various pharmaceutical compounds and inhibitors. Substituted carboxamides are synthesized using Ethanolamine that show potent antitumor activity. Also used in the synthesis of aminoquinolones which display anti-plasmodial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);<br></p>

<p>Applications 5-Hydroxytryptamine (cas# 50-67-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-(N-Ethyl-N-2-hydroxyethylamino)-2-penthlamine is a useful synthetic intermediate in the synthesis of Hydroxy Chloroquine (H905300/H905305); a major metabolite of Chloroquine (C379965, diphosphate salt) which is a standard anti-malarial drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003); Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003); Huang, S., et al.: Talanta, 64, 887 (2004); Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983); Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998); Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999)<br></p>

<p>Applications N-(Benzyloxycarbonyl)ethanolamine is an intermediate used to prepare alkynylaryladenines as A2A adenosine receptor agonists and effects on hepatic glucose production. It is also used in the synthesis of functionalized N-arylaminoethyl amides as noncovalent inhibitors of cathepsin S.<br>References Harada, H., et al.: Bioorg. Med. Chem., 9, 2709 (2001); Tully, D., et al.: Bioorg. Med. Chem. Lett., 16, 5112 (2006)<br></p>

<p>Applications α-Isopropylbenzylamine Hydrochloride is used in the synthetic preparation of arylalkylamines by addition of Grignard reagents to phosphorylaldimines.<br>References Zwierzak, A., Napieraj, A.: Synthesis, 6, 930 (1999)<br></p>

<p>Applications Has a DNA binding effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mikata, Y., et al.: Chem. Pharm. Bull., 48, 477 (2000),<br></p>

<p>Applications 3,3′-Diaminobenzidine is a peroxidase substrate and a reagent for spectrophotometric determination of selenium.<br></p>

<p>Stability hygroscopic<br>Applications 3-Amino-1-propanol is used in the synthesis of tetrathiafulvalenes displaying optical and electrochemical properties. Also used in the synthesis of lipid-like materials for the delivery and encapsulation of RNAi therapeutics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ignatenko, E. et al.: Russ. J. Org. Chem., 49, 1379 (2013); Akinc, A. et al.: Nat. Biotech., 26, 561 (2008);<br></p>

<p>Stability Hygroscopic<br>Applications Used in the manufacturing of L-tryptophan by enzymic reaction.<br>References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),<br></p>

<p>Applications 4-(diethylamino)benzophenone (cas# 18127-87-2) is a useful research chemical.<br></p>

<p>Applications Ethylamine Solution is used as a reagent in the synthesis of a series of hexadentate ligands as potential antibacterial agents. Also used as a reagent in the synthesis of tetrahydrothiazolopyridine derivatives as potent smoothened antagonists.<br>References Zhang, M., et al.: Chem. Biol. Drug Des., 84, 659 (2014); Ma, H., et al.: Eur. J. Med. Chem., 89, 721 (2015)<br></p>

<p>Applications 2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.<br>References Lacotte, P. et al.: ChemMedChem, 8, 104 (2013); Klein, J. et al.: Org. Lett., 14, 330 (2012);<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications 4-Aminophenylphosphorylcholine (cas# 102185-28-4) is a compound useful in organic synthesis.<br>References Bruderer, U., et al.: Mol. Immunol., 26, 63 (1989),<br></p>

<p>Stability Hygroscopic<br>Applications N-(2-Chloroethyl)-1,2-ethanediamine Dihydrochloride is an analog of 2-(2-Aminoethylamino)ethanol (A608990); a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Also used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013)<br></p>

<p>Applications 6-[(6-Aminohexyl)amino]-6-oxo-hexanoic acid is a nylon oligomer with flame retardant properties.<br>References Zahn, Helmut et al.: Chemische Berichte, 92, 1381 (1959)<br></p>

<p>Applications 2-Amino-2-thiazoline (cas# 1779-81-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Aminobutanol is used in the preparation of CDK inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, J. et al.: Chin. J. Chem., 31, 1181 (2013); Tahghighi, A. et al.: J. Enz. Inhib. Med. Chem., 28, 843 (2013);<br></p>

<p>Applications Diammonium salt of Phosphoric Acid, used in various chemical processes as a phosphorylating compound. Also used in the preparation of prosthetics and collagen nanocomposites due to the bone-like properties.<br>References Ezhova, Z. et al.: Russ. J. Inorg. Chem., 58, 1177 (2013); Wu, Y. et al.: Asian J. Chem., 25, 5881 (2013);<br></p>

<p>Stability Hygroscopic<br>Applications Neamine is normally found as a core structure of aminoglycoside antibiotics. It is used in the synthesis of disaccharide neamine derivatives as antibacterial agents.<br>References Kawaguchi, H., et al.: J. Antibiot., 25, 695 (1972), Fourmy, D., et al.: Science, 274, 1367 (1996), Riguet, E., et al.: J. Med. Chem., 47, 4806 (2004)<br></p>