Cyano-, Nitrile-

<p>Applications N-(3-Chloro-4-fluorophenyl)-2-cyanoacetamide (cas# 219529-31-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes.<br>References Rafiee, M., et al.: J. Electroanal. Chem., 626, 36 (2009); Deng, J., et al.: Eur. J. Med. Chem., 46, 71 (2010)<br></p>

<p>Applications Ethyl 2-Cyanopropanoate is a building block used in many organic reactions such as the preparation of highly substituted benzenes.<br>References Zhang, X., et. al.: Organic Lett., 13, 5024 (2011)<br></p>

<p>Applications Tetrakis(acetonitrile)palladium Bis(tetrafluoroborate) is used to prepare an α-Diimine-transition metal complex, which is used as a catalyst for polymerization of olefins. It is also a catalyst used in cross coupling reaction for C-C, C-O, and C-N bond formation.<br>References Feldman, J., et al.: Organometallics, 16, 1514 (1997); Johnson, L., et al.: PCT Int. Appl., WO 9623010 A2 19960801 (1996); Poppenbery, J., et al.: Surface Sci., 2011; Pijnenburg, N., et al.: Dalton Transactions, 40, 8896 (2011); Kilpin, K., et al.: Inorg. Chem., 50, 6334 (2011)<br></p>

<p>Applications N-(β-Cyanoethyl)-N-(ethoxycarbonylethyl)benzylamine is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Cyanophenol is used in a study to assess chemical uptake into human stratum corneum.<br>References Stinchcomb, A.L., et. al.: Pharm. Res., 16, 1288 (1999)<br></p>

<p>Applications Phthalodinitrile monomers can be polymerized thermally in the presence of small amounts of curing agents into thermosetting polymers. Phthalodinitrile is a precursor to phthalocyanine which is used as a dye or pigment.<br>References Sastri, S. B. and Keller, T. M.: J. Polym. Sci. A Polym. Chem., 36, 1885-1890(1998), Löbbert, G. Phthalocyanines. In Ullmann's Encyclopedia of Industrial Chemistry, (Ed.)., (2000).<br></p>

<p>Applications Ethyl Cyanoformate (cas# 623-49-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Cyano-N-((furan-2-ylmethyl)carbamoyl)acetamide is an intermediate in the synthesis of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.<br>References Balo, M. C., et al.: Bioorg. Med. Chem., 17, 6755 (2009);<br></p>

<p>Applications Methyl cyanoformate is a reagent that is used in the preparation of XEN907, which is a spiro-oxindole blocker of Nav1.7 for the treatment of pain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chowdhury, S., et al.: Bioorg. Med. Chem. Lett., 21, 3676 (2011);<br></p>

<p>N-Cyanopyrrolidine is a compound that targets enzymes, such as histone deacetylases (HDACs) and protein kinase C. It is a chemical ionization reagent that reacts with hydroxyl groups on the target molecule. This leads to the formation of covalent bonds between the target and the reagent, which results in an irreversible reaction. N-Cyanopyrrolidine has been shown to have antidiabetic effects in diabetic patients and hiv infection by decreasing levels of glucose in the blood. It also inhibits cancer cell growth by inhibiting dpp-IV, which is an enzyme that causes cancer cells to proliferate.</p>

Cyanoacetic acid is an antimicrobial agent that can be used for the treatment of bowel disease, autoimmune diseases, and eye disorders. Cyanoacetic acid is a substrate molecule for sodium carbonate, which can be used to produce sodium carbonate by reacting with water. The reaction solution is then added to human serum or malonic acid to produce sodium carbonate, which can be used as a drug. Electrochemical impedance spectroscopy has been used as a tool to study the mechanism of cyanoacetic acid in treating inflammatory bowel disease.

3-Cyanomethylbenzoic acid methyl ester is a synthetic chemical compound that is used as an intermediate in the production of other chemicals. It is a chlorination agent that reacts with toluene and methanol in the presence of chlorine to produce 3-chloromethylbenzoic acid methyl ester. This reaction also produces a byproduct called sulphone, which can be converted into acylation reagents for use in organic synthesis. The chloride ion can be used for cyanation reactions, which are useful for producing dyes or pharmaceuticals.

<p>3-Cyano-2-hydroxypyridine is an inhibitor of the noradrenaline transporter, which is a type of l-type calcium channel. 3-Cyano-2-hydroxypyridine has been shown to be a potent inhibitor of the noradrenaline transporter. It inhibits the binding of neurotransmitters to their receptors by blocking active methylene sites on the transporter molecule. This drug also has a cavity that can accommodate bulky inhibitor molecules, making it more difficult for these inhibitors to bind to the active site and compete with neurotransmitters for uptake. 3Cyano-2-hydroxypyridine also inhibits nitric oxide synthase, which may provide anti-tumor activity as well as inhibit tumor cell growth. The inhibitory effect of this drug is due to structural studies that have revealed hydrogen bonding interactions with the drug's nitrogen and oxygen atoms.</p>