Halogenated Compounds

<p>Applications 4-Iodo-N,N-dimethylaniline is a useful reactant for organic reactions and the synthesis of various compounds.<br>References Luo, X., et al.: Org. Lett., 20, 2997-3000 (2018); Hamasaka, G., et al.: Adv. Synth. Catal., 360, 1833-40 (2018);<br></p>

<p>Applications 2-Amino-4-chloro-5-methylbenzenesulfonic Acid is used in method for preparing environment-friendly organic pigment for agricultural seed coating.<br>References Xu, C., et al.: Faming Zhuanli Shenqing, (2020);<br></p>

<p>Applications Perfluoro-n-pentane (CAS# 678-26-2) is a useful research chemical compound.<br></p>

<p>Applications 5-Fluoroorotic acid hydrate (cas# 207291-81-4) is a useful research chemical.<br></p>

<p>Applications 2-Amino-5-chloro-N,3-dimethylbenzamide is the key intermediate used in the synthesis of chlorantraniliprole, a novel insecticide.<br>References Zhang, T., et al.: Jingxi Huagong Zhongjianti, 40, 17 (2010); Peng, Y., et al.: Nongyao, 48, 326 (2009)<br></p>

<p>Applications 2,3,4,5,6-Pentachlorotoluene is used in prediction of daphnid survival after in situ exposure to complex mixtures. Also, this compound is very toxic.<br>References Baas, J., et al.: Environmental Science &amp; Technology, 43, 6064-6069 (2009);<br></p>

<p>Applications 1,4-Dichlorocyclohexane is a solvent used in the synthesis of chemical foamed polysulfide sealants for aerospace fuel tank use.<br>References Stevens, B. E. et al.: U.S. Pat. Appl. Publ. 18 pp. (2017)<br></p>

<p>Applications Bromoacetic Acid-d2 is the isotopically labeled form of 2-Bromoacetic Acid(B679075) which is is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>

<p>Applications 2-chlorobenzene-1,4-diamine (cas# 615-66-7) is a useful research chemical.<br></p>

<p>Applications 1-(4-Chloro-phenyl)-4,4-dimethyl-3-(1,3,4-triazol-1-yl-methyl)-pentan-3-ol is used in method for the addition of anti-microbial compounds to fiberglass insulation products.<br>References Delaviz, Y., et al.: U.S. Pat. Appl. Publ., (2004);<br></p>

<p>Applications 8-Hydroxy-7-iodoquinoline-5-sulfonic acid (cas# 547-91-1) is a useful research chemical.<br></p>

<p>Applications 1,3-Dichlorocyclohexane is a solvent used in the synthesis of chemical foamed polysulfide sealants for aerospace fuel tank use.<br>References Stevens, B. E. et al.: U.S. Pat. Appl. Publ. 18 pp. (2017)<br></p>

<p>Applications Methyl 5-Chloro-1-oxo-2,3-dihydro-1H-indene-2-carboxylate is an intermediate in the synthesis of IN-KG 433 (I627995) which is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.<br>References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);<br></p>

<p>Applications cyclopropyl(4-fluorophenyl)methanone (cas# 772-31-6) is a useful research chemical.<br></p>

<p>Applications Difluoromethyl 2,2,2-Trifluoroethyl Ether can be used as a secondary battery separator layer, electrode structure, and secondary battery.<br>References Kadota, A., et.al.,Jpn. Kokai Tokkyo Koho, 19, (2020);<br></p>

<p>Applications 3,4-Dichlorobenzenesulfonamide (cas# 23815-28-3) is a useful research chemical.<br></p>

<p>Applications 2,2',5'-Trichloroacetophenone is a useful research chemical for organic synthesis and other chemical processes.<br>References Xu, L., et al.: Chem. Res. Chin. Univ., 24, 299 (2008); Song, W., et al.: MedChemComm, 7, 1441 (2016)<br></p>

<p>Applications 3-Chloro-N-methylpropan-1-amine Hydrochloride can be used as reactant/reagent in oxidative metabolism of ferrocene analogs of tamoxifen: characterization and antiproliferative activities of metabolites.<br>References Richard, M. A., et al.: ChemMedChem, 10, 981-990 (2015)<br></p>

<p>Applications Diethyl 2-(4-Chlorobutyl)malonate it's structure activity studies on 1,3-Dioxane-2-carboxylic Acid derivitives, a class of subtype-selective Peroxisome Proliferator-Activated Receptor α (PPARα) agonists.<br>References Asaki, T., et al.: Bioorganic &amp; Medicinal Chemistry, 16, 981-994 (2008);<br></p>

<p>Applications Bromopentafluorobenzene is a polyfluorinated chemical that is widely distributed in the environment and released because of its use in different household and industrial products. Bromopentafluorobenzene is also used in the synthesis of phenylproparginols which have herbicidal activity.<br>References Bhhatarai, B., et al.: Chem. Res. Toxicol., 23, 528 (2010); Parlow, J.J., et al.: J. Agr. Food Chem., 42, 2600 (1994)<br></p>

<p>Applications Perfluorododecyl Iodide self-assemble on a silicon nitride which are compatible with several applications such as biosensing.<br>References Abate, Antonio. et al., J. Mater. Chem. B. 7, 24445-24453(2019);<br></p>

<p>Applications 2,4-Dibromobutyric acid (cas# 63164-16-9) is a useful research chemical.<br></p>

<p>Applications 17-Iodoandrosta-5,16-dien-3β-ol is used in synthesis of Oxoabiraterone Acetate.Also, in preparation of Abiraterone Acetate.<br>References Yuan, X., et al.: Faming Zhuanli Shenqing, (2020); Xia, R., et al.; Faming Zhuanli Shenqing, (2019);<br></p>

<p>Applications 2-[(4-fluorobenzyl)amino]ethanol (cas# 22116-33-2) is a useful research chemical.<br></p>

<p>Applications Pentachlorothiophenol is plasticizer; is used in method for preparing outer rubber hose for high performance hydraulic oil pipe.<br>References Jun, F., et al.: Faming Zhuanli Shenqing, (2019);<br></p>

<p>Stability Hygroscopic<br>Applications Labelled analogue of Chlorocholine Chloride, a plant growth regulator that is primarily used on ornamental plants.<br>References Pinto, A.C.R. et al.: Acta Horticult., 683, 399 (2005); Gu, Z. et al.: Hun. Nong. Dax. Xueb., 35, 383 (2009); Xing, S. et al.: J. Med. pLant Res., 5, 1962 (2011);<br></p>

<p>Applications Bis(2-​chloroethyl) (2-​Chloroethyl)​phosphonate is used in the production of 2-​Chloroethylphosphonic acid which is used as a plant regulator in agriculture.<br>References Cauret, L. et al.: Bull. Soc. Chim. France., 134, 463 (1997);<br></p>

<p>Applications 4-Chloro-2,6-dimethylphenol is a useful research chemical for organic synthesis and other chemical processes.<br>References Qin, Z., et al.: Youji Huaxue, 23, 654 (2003); Gu, Y., et al.: Fenzi Kexue Xuebao, 29, 212 (2013); Schroetter, E., et al.: Pharmazie, 32, 171 (1977);<br></p>

<p>Applications 2,4,5-Trichloronitrobenzene- 13C6 is the labeled form of 2,4,5-Trichloronitrobenzene(T774310). It is an intermediate in the synthesis of PCB 101-13C12 (P216628) which is a related compound of PCB 189-13C12(P216622), which is a flame retardant and a standard for environmental testing and research.<br>References EPA. Method 1668, (EPA 821-R-00-002) (1999)<br></p>

<p>Applications 5-Chloro-2-hydroxybenzyl alcohol (cas# 5330-38-1) is a useful research chemical.<br></p>

<p>Applications 4-CHLORO-3-NITROANISOLE (cas# 10298-80-3) is a useful research chemical.<br></p>

<p>Applications 2,4,5-Trichloroaniline-13C6 is the labeled form of 2,4,5-Trichloroaniline(T774090). It is an intermediate in the synthesis of PCB 101-13C12 (P216628) which is a related compound of PCB 189-13C12(P216622), which is a flame retardant and a standard for environmental testing and research.<br>References EPA. Method 1668, (EPA 821-R-00-002) (1999)<br></p>

<p>Applications 2-(4-CHLOROBENZYL)PYRIDINE (cas# 4350-41-8) is a useful research chemical.<br></p>

<p>Applications (5E)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).<br></p>

<p>Applications 2,3,5-Trimethoxybromobenzene is an intermediate in the synthesis of 2,3,5-Trimethoxyamphetamine (T896885) which is a derivative of Amphetamine (A634240), CNS stimulant; anorexic.Controlled substance (stimulant).<br>References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 85, 119 (1945); Behrendt, W.A, et al.: Arzneim.-Forsch., 13, 711 (1963); Seiden, L.S., Annu. Rev. Pharmacol. Toxicol., 32, 639 (1993)<br></p>

<p>Applications 6-Chloro-N2-methyl-1,3,5-triazine-2,4-diamine is a reagent in the synthesis of N-Methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine (M330478) which is a useful research chemical.<br>References List, M., et al.: J. Org. Chem., 81(10), 4066-4075 (2016)<br></p>

<p>Applications Chloromethyl Dimethylcarbamate is a useful realgent for synthesis in (Acyloxyalkyl)pyridinium salts as soluble prodrugs of a potent pyrrolothiazole platelet activating factor antagonist.<br>References Davidsen, S., et al.: J. Med. Chem., 37, 4423 (1994);<br></p>

<p>Applications 4-Chloronitrobenzene-13C6 is the labeled form of 4-Chloronitrobenzene(C373910). It is an intermediate in the synthesis of PCB 101-13C12 (P216628) which is a related compound of PCB 189-13C12(P216622), which is a flame retardant and a standard for environmental testing and research.<br>References EPA. Method 1668, (EPA 821-R-00-002) (1999)<br></p>

<p>Applications Copper (II) trifluoroacetate hydrate (cas# 123333-88-0) is a useful research chemical.<br></p>

<p>Applications (3-chlorophenyl)(phenyl)methanol (cas# 63012-03-3) is a useful research chemical.<br></p>

<p>Applications (1R-4S)-N-[4-chloro-5-(formylamino)-6-[[4-(hydroxymethyl)-2-cyclopenten-1-yl]amino]-2-pyrimidinyl]acetamide, is a precursor of (1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride (A603506), which is an intermediate for the synthesis of Abacavir (A105000) (1,2,3).<br>References (1) Daluge, S.M., et al.: Antimicrob. Ag. Chemother., 41, 1082 (1997) (2) Foster, R.H., et al.: Drugs, 55, 729 (1998) (3) Staszewski, S., et al.: J. Am. Med. Assoc., 285, 1155 (2001)<br></p>

<p>Applications 5-Chloro-3-[(methylamino)sulfonyl]-2-thiophenecarboxylic Acid is an intermediate in preparation of Lornoxicam.<br>References Fan, W., et al.: Zhon. Yiy. Gon. Zaz., 33, 365-366 (2002);<br></p>

<p>Applications 1,4-Diiodotetrafluorobenzene (cas# 392-57-4) is a reagent for synthesis of N-​aryl amides from O-protected hydroxamic acids.<br>References Broumidis, E., et al.: ChemPlusChem, 85, 1754 (2020)<br></p>

<p>Applications 2,6-Dibromo-4-cyanophenyl Heptanoate-d13 is a useful isotopically labeled compound<br></p>

<p>Applications 2-Iodo-5-methoxypyrazine is a reactant used in the preparation of substituted azaspiro[4.5]​decane derivatives with affinity to opioid receptors.<br>References Wegert, A. et al.: PCT Int. Appl. (2016), WO 2016008582 A1 20160121.<br></p>

<p>Applications 1-Bromohexane-5,5,6,6,6-d5 is a useful isotopically labeled compound of 1-Bromohexane (B683950)<br></p>

<p>Applications 1,1-Dichloroethylene-d2 (CAS# 22280-73-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications (1Z,1’Z)-Dimethyl-1,1’-(hydrazine-1,2-diylidene)bis(5-chloro-2-hydroxy-2,3-dihydro-1H-indene-2-carboxylate) is an intermediate in the synthesis of IN-KG 433 (I627995) which is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.<br>References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);<br></p>

<p>Applications 3,3,3-Trideuterio-2,2-difluoro-propanoic acid is a useful labeled building block.<br></p>

<p>Applications N1-(3-Aminopropyl)-N1-(2-bromoethyl)propane-1,3-diamine is a useful research chemical.<br></p>

<p>Applications 3-((5-Chloropyridin-2-yl)carbamoyl)pyrazin-2-yl)methyl 4-methylpiperazine-1-carboxylate is a useful synthesis intermediate.<br></p>

<p>Applications 2,3-Dichlorobenzenesulfonamide (cas# 82967-94-0) is a useful research chemical.<br></p>

<p>Applications 3,6-Dichloro-2-pyridinol can be used for various preparatory reactions, including photodegradations of chlorpyrifos in TiO2 suspensions.<br>References Sojic, D., et.al., J. Hazard. Mater., 168,94-101,(2009);<br></p>

<p>Applications 3,3-Difluorocyclopentanecarboxylic Acid is an intermediate in preparation of linked bisimidazoles, bisbenzimidazoles and analogs.<br>References Hewawasam, P., et al.: PCT Int. Appl. (2013), WO 2013106520 A1 20130718.<br></p>

<p>Applications (3R)-3-Fluoropyrrolidine-1-sulfonyl Chloride is used as a reagent in the preparation of heterocyclic compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides.<br>References Crew, A. P., et al.: PCT Int. Appl. 1014pp. (2018)<br></p>

<p>Applications 5-Bromo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid is a useful research chemical.<br></p>

<p>Applications 2,4,5-Trichlorophenacylidene Chloride is an intermediate in the synthesis of 2,4,5-Trichlorophenylethanediol (T382940); a metabolite of Tetrachlorvinphos (T292305). 2,4,5-Trichlorophenylethanediol is the byproduct of Tetrachlorvinphos being consumed by Dogs and Rats.<br>References Zhao, F., et al.: Anal. Bioanal. Chem., 408, 6423 (2016); Akintonwa,D., et al.: J Agr Food Chem., 15, 632-637 (1967)<br></p>

<p>Applications 2-(2-Bromoethoxy)Anisole (cas# 4463-59-6) is a useful research chemical.<br></p>

<p>Applications 2-(Chloromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one (CAS# 3166-54-9) is a useful research chemical compound.<br></p>

<p>Applications 2,2-Dibromo-1-cyclopropyl-2-(2-fluorophenyl)-ethanone is a useful research chemical.<br></p>

<p>Applications cis-3-Acetoxy-6-chlorocyclohexene is used as a reagent in the diastereoselective preparation of analogs of hydroxyoctahydroindolecarboxylates with 4,5- or 6,7-unsatturation using palladium-catalyzed allylations as key steps.<br>References Mao, Z., et al.: Tetrahedron Lett. 58, 4174 (2017)<br></p>

<p>Applications 2-Fluorobenzal Chloride is an important reagent in the synthesis of Benzenesulfonyl fluoride derivatives.<br>References Davies, W., et al.: J. Chem. Soc., 2042-2046 (1932)<br></p>

<p>Applications 1-bromo-2-(1,1-difluoroethyl)benzene (cas# 444581-46-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-Chloro-N-methyl-1H-indole-3-ethanamine is useful for the synthetic preparation of carbolinones.<br>References Han, H., et al.: J. Org. Chem., 84, 3357 (2019)<br></p>

<p>Applications 4-Bromo-2(3H)-benzoxazolone is a reagent used in the preparation of ceramidase Inhibitors.<br>References Bach, A., et al.: J. Med. Chem., 58, 9258-9272 (2015)<br></p>

<p>Applications Carboxylic Acids are used in preparation of Carboxylic acids via hydrocarboxylation/boration of alkenes/boronic acid pinacol esters with CO 2 using biomass-derived solvents.<br>References Gevorgyan, A., et al.: ChemSusChem, (2020);<br></p>

<p>Applications 2-Fluoro-3-nitrobenzoic Acid is used in preparation of bifunctional Heterocycles and their use in targeted degrdn. of RAF polypeptides.<br>References Crew, Andrew P., et al.: U.S. Pat. Appl. Publ., (2020);<br></p>

<p>Applications 2,6-Bis(trifluoromethyl)phenol is a useful intermediate for the preparation of tebufelone analogs.<br>References Miller, J. A., et al.: J. Org. Chem., 58, 2637 (1993)<br></p>