Halogenated Compounds

Applications 1-(4-Chloro-phenyl)-4,4-dimethyl-3-(1,3,4-triazol-1-yl-methyl)-pentan-3-ol is used in method for the addition of anti-microbial compounds to fiberglass insulation products.
References Delaviz, Y., et al.: U.S. Pat. Appl. Publ., (2004);

Applications 3-(4-Chlorophenyl)propan-1-ol is used in preparation of 2-Oxo-2H-chromene-3-carboxylic Acid Amide derivatives as Aldo-Keto reductase inhibitors.
References Toyooka, N., et al.: Jpn. Kokai Tokkyo Koho, (2018);

Applications 1,3-Dichlorocyclohexane is a solvent used in the synthesis of chemical foamed polysulfide sealants for aerospace fuel tank use.
References Stevens, B. E. et al.: U.S. Pat. Appl. Publ. 18 pp. (2017)

Applications Bromoacetic Acid-d2 is the isotopically labeled form of 2-Bromoacetic Acid(B679075) which is is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.
References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);

Applications (Z)-Methyl 5-Chloro-1-hydrazono-2-hydroxy-2,3-dihydro-1H-indene-2-carboxylate is an intermediate in the synthesis of IN-KG 433 (I627995) which is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.
References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);

Applications 17-Iodoandrosta-5,16-dien-3β-ol is used in synthesis of Oxoabiraterone Acetate.Also, in preparation of Abiraterone Acetate.
References Yuan, X., et al.: Faming Zhuanli Shenqing, (2020); Xia, R., et al.; Faming Zhuanli Shenqing, (2019);

Applications Methyl 5-Chloro-1-oxo-2,3-dihydro-1H-indene-2-carboxylate is an intermediate in the synthesis of IN-KG 433 (I627995) which is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.
References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);

Applications cyclopropyl(4-fluorophenyl)methanone (cas# 772-31-6) is a useful research chemical.

Applications 4,4-Dibromo-2,4-dihydro-5-methyl-3H-pyrazol-3-one is used in the preparation of antimoebic compounds such as thiosemicarbazide derivatives. Also used in the preparation of triazine molecules displaying antifungal activity.
References Singh, S. et al.: Eur. J. Pharm. Sci., 25, 255 (2005); Tewari, A. et al.: Indian. J. Chem. B., 41B, 664 (2002);

Applications Bis(2-​chloroethyl) (2-​Chloroethyl)​phosphonate is used in the production of 2-​Chloroethylphosphonic acid which is used as a plant regulator in agriculture.
References Cauret, L. et al.: Bull. Soc. Chim. France., 134, 463 (1997);

Applications 2,4,5-Trifluorophenylacetonitrile (cas# 220141-74-2) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 8-Hydroxy-7-iodoquinoline-5-sulfonic acid (cas# 547-91-1) is a useful research chemical.

Applications 2,4-Dibromobutyric acid (cas# 63164-16-9) is a useful research chemical.

Applications 2,3,4,5,6-Pentachlorotoluene is used in prediction of daphnid survival after in situ exposure to complex mixtures. Also, this compound is very toxic.
References Baas, J., et al.: Environmental Science & Technology, 43, 6064-6069 (2009);

Applications Perfluorododecyl Iodide self-assemble on a silicon nitride which are compatible with several applications such as biosensing.
References Abate, Antonio. et al., J. Mater. Chem. B. 7, 24445-24453(2019);

Applications 2,2',5'-Trichloroacetophenone is a useful research chemical for organic synthesis and other chemical processes.
References Xu, L., et al.: Chem. Res. Chin. Univ., 24, 299 (2008); Song, W., et al.: MedChemComm, 7, 1441 (2016)

Applications 1-Chloro-2,4-dinitrobenzene- 13C6 is the labeled form of 1-Chloro-2,4-dinitrobenzene (C365860). It is a byproduct in the synthesis of 1,4-Dichlorobenzene-13C6(D431878) which is a versatile building block and a small bioactive molecule, used in various organic synthesis. It is also used as disinfectant, deodorant, and pesticide.
References Fahey, D. R., et al.: Macromolecules, 24 (15), 4242 (1991); Rossberg, M., et al.: Ullmann's Encyclopedia of Industrial Chemistry, (2006);

Applications 5-(4'-(Dibromomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole is a reagent in the preperation of sartan lateral chain compounds.
References Yan, Q.: Faming Zhuanli Shenqing. 7 pp. (2009)

Stability Hygroscopic
Applications Labelled analogue of Chlorocholine Chloride, a plant growth regulator that is primarily used on ornamental plants.
References Pinto, A.C.R. et al.: Acta Horticult., 683, 399 (2005); Gu, Z. et al.: Hun. Nong. Dax. Xueb., 35, 383 (2009); Xing, S. et al.: J. Med. pLant Res., 5, 1962 (2011);

Applications Bromocyclopentane, is an organic reagent that can be used as both the starting material and an intermediates in the chemical synthesis. It can be used as an starting material in the synthesis of Glycopyrrolate Bromide (G656980), which is a is a medication of the muscarinic anticholinergic group.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kaltiala, E., et al.: J. Pharm. Pharmacol., 26, 352 (1974), Kongsrud, F., et al.: Acta Anaesthesiol. Scand., 26, 620 (1982),

Applications Bromopentafluorobenzene is a polyfluorinated chemical that is widely distributed in the environment and released because of its use in different household and industrial products. Bromopentafluorobenzene is also used in the synthesis of phenylproparginols which have herbicidal activity.
References Bhhatarai, B., et al.: Chem. Res. Toxicol., 23, 528 (2010); Parlow, J.J., et al.: J. Agr. Food Chem., 42, 2600 (1994)

Applications Chloromethyl Dimethylcarbamate is a useful realgent for synthesis in (Acyloxyalkyl)pyridinium salts as soluble prodrugs of a potent pyrrolothiazole platelet activating factor antagonist.
References Davidsen, S., et al.: J. Med. Chem., 37, 4423 (1994);

Applications 2,4,5-Trichloroaniline-13C6 is the labeled form of 2,4,5-Trichloroaniline(T774090). It is an intermediate in the synthesis of PCB 101-13C12 (P216628) which is a related compound of PCB 189-13C12(P216622), which is a flame retardant and a standard for environmental testing and research.
References EPA. Method 1668, (EPA 821-R-00-002) (1999)

Applications (3-chlorophenyl)(phenyl)methanol (cas# 63012-03-3) is a useful research chemical.

Applications 4-Chloronitrobenzene-13C6 is the labeled form of 4-Chloronitrobenzene(C373910). It is an intermediate in the synthesis of PCB 101-13C12 (P216628) which is a related compound of PCB 189-13C12(P216622), which is a flame retardant and a standard for environmental testing and research.
References EPA. Method 1668, (EPA 821-R-00-002) (1999)

Applications 4-Chloro-2,6-dimethylphenol is a useful research chemical for organic synthesis and other chemical processes.
References Qin, Z., et al.: Youji Huaxue, 23, 654 (2003); Gu, Y., et al.: Fenzi Kexue Xuebao, 29, 212 (2013); Schroetter, E., et al.: Pharmazie, 32, 171 (1977);

Applications 4-CHLORO-3-NITROANISOLE (cas# 10298-80-3) is a useful research chemical.

Applications 5-Chloro-2-hydroxybenzyl alcohol (cas# 5330-38-1) is a useful research chemical.

Applications Copper (II) trifluoroacetate hydrate (cas# 123333-88-0) is a useful research chemical.

Applications 2,3,5-Trimethoxybromobenzene is an intermediate in the synthesis of 2,3,5-Trimethoxyamphetamine (T896885) which is a derivative of Amphetamine (A634240), CNS stimulant; anorexic.Controlled substance (stimulant).
References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 85, 119 (1945); Behrendt, W.A, et al.: Arzneim.-Forsch., 13, 711 (1963); Seiden, L.S., Annu. Rev. Pharmacol. Toxicol., 32, 639 (1993)

Applications (5E)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

Applications 2,4,5-Trichloronitrobenzene- 13C6 is the labeled form of 2,4,5-Trichloronitrobenzene(T774310). It is an intermediate in the synthesis of PCB 101-13C12 (P216628) which is a related compound of PCB 189-13C12(P216622), which is a flame retardant and a standard for environmental testing and research.
References EPA. Method 1668, (EPA 821-R-00-002) (1999)

Applications 2-(4-CHLOROBENZYL)PYRIDINE (cas# 4350-41-8) is a useful research chemical.

Applications 3-(Trifluoromethyl)phenylhydrazine (cas# 368-78-5) is a useful research chemical.

Applications 4-Difluoromethoxy-1,2-phenylendiamine is used in preparation of benzimidazole derivatives as TRPC6 inhibitors
References Batberger, M., et al., PCT Int. Appli, (2018),

Applications Ethyl-5-iodovalerate is a reagent in the synthesis of 8-Amino-7-oxopelargonic Acid Hydrochloride (A618750) which is an intermediate in the synthesis of biotin. Pimeloyl-CoA is transformed into AOP in the presence of L-alanine by the enzyme AOP synthase. The catalytic mechanism of AOP synthase has been studied for the elucidation of inhibitors as potential antimicrobial agents.
References Ohsugi, M., et al.: J. Nutr. Sci. Vitaminol., 34 (4), 343 (1985), Pearson, B.M., et al.: Lett. Appl. Microbiol., 10 (2), 89 (1990), Ploux, O., et al.: Biochem. J., 283, 327 (1992)

Applications 5-Chloro-2-methyl-thieno[2,3-d]-isothiazolidin-3-one-1,1-dioxide is a useful research chemical.

Applications 6-Iodo-nicotinic acid (cas# 13054-02-9) is a useful research chemical.

Applications (1R-4S)-N-[4-chloro-5-(formylamino)-6-[[4-(hydroxymethyl)-2-cyclopenten-1-yl]amino]-2-pyrimidinyl]acetamide, is a precursor of (1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride (A603506), which is an intermediate for the synthesis of Abacavir (A105000) (1,2,3).
References (1) Daluge, S.M., et al.: Antimicrob. Ag. Chemother., 41, 1082 (1997) (2) Foster, R.H., et al.: Drugs, 55, 729 (1998) (3) Staszewski, S., et al.: J. Am. Med. Assoc., 285, 1155 (2001)

Applications 5-Chloro-3-[(methylamino)sulfonyl]-2-thiophenecarboxylic Acid is an intermediate in preparation of Lornoxicam.
References Fan, W., et al.: Zhon. Yiy. Gon. Zaz., 33, 365-366 (2002);

Applications 1,4-Diiodotetrafluorobenzene (cas# 392-57-4) is a reagent for synthesis of N-​aryl amides from O-protected hydroxamic acids.
References Broumidis, E., et al.: ChemPlusChem, 85, 1754 (2020)

Applications 2,6-Dibromo-4-cyanophenyl Heptanoate-d13 is a useful isotopically labeled compound

Applications 2-Iodo-5-methoxypyrazine is a reactant used in the preparation of substituted azaspiro[4.5]​decane derivatives with affinity to opioid receptors.
References Wegert, A. et al.: PCT Int. Appl. (2016), WO 2016008582 A1 20160121.

Applications 1-Bromohexane-5,5,6,6,6-d5 is a useful isotopically labeled compound of 1-Bromohexane (B683950)

Applications 1,1-Dichloroethylene-d2 (CAS# 22280-73-5) is a useful isotopically labeled research compound.

Applications (1Z,1’Z)-Dimethyl-1,1’-(hydrazine-1,2-diylidene)bis(5-chloro-2-hydroxy-2,3-dihydro-1H-indene-2-carboxylate) is an intermediate in the synthesis of IN-KG 433 (I627995) which is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.
References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);

Applications 3,3,3-Trideuterio-2,2-difluoro-propanoic acid is a useful labeled building block.

Applications N1-(3-Aminopropyl)-N1-(2-bromoethyl)propane-1,3-diamine is a useful research chemical.

Applications 3-((5-Chloropyridin-2-yl)carbamoyl)pyrazin-2-yl)methyl 4-methylpiperazine-1-carboxylate is a useful synthesis intermediate.

Applications 2,3-Dichlorobenzenesulfonamide (cas# 82967-94-0) is a useful research chemical.

Applications 3,6-Dichloro-2-pyridinol can be used for various preparatory reactions, including photodegradations of chlorpyrifos in TiO2 suspensions.
References Sojic, D., et.al., J. Hazard. Mater., 168,94-101,(2009);

Applications 3,3-Difluorocyclopentanecarboxylic Acid is an intermediate in preparation of linked bisimidazoles, bisbenzimidazoles and analogs.
References Hewawasam, P., et al.: PCT Int. Appl. (2013), WO 2013106520 A1 20130718.

Applications (3R)-3-Fluoropyrrolidine-1-sulfonyl Chloride is used as a reagent in the preparation of heterocyclic compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides.
References Crew, A. P., et al.: PCT Int. Appl. 1014pp. (2018)

Applications 5-Bromo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid is a useful research chemical.

Applications 2,4,5-Trichlorophenacylidene Chloride is an intermediate in the synthesis of 2,4,5-Trichlorophenylethanediol (T382940); a metabolite of Tetrachlorvinphos (T292305). 2,4,5-Trichlorophenylethanediol is the byproduct of Tetrachlorvinphos being consumed by Dogs and Rats.
References Zhao, F., et al.: Anal. Bioanal. Chem., 408, 6423 (2016); Akintonwa,D., et al.: J Agr Food Chem., 15, 632-637 (1967)

Applications 2-(2-Bromoethoxy)Anisole (cas# 4463-59-6) is a useful research chemical.

Applications 2-(Chloromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one (CAS# 3166-54-9) is a useful research chemical compound.

Applications 2,2-Dibromo-1-cyclopropyl-2-(2-fluorophenyl)-ethanone is a useful research chemical.

Applications cis-3-Acetoxy-6-chlorocyclohexene is used as a reagent in the diastereoselective preparation of analogs of hydroxyoctahydroindolecarboxylates with 4,5- or 6,7-unsatturation using palladium-catalyzed allylations as key steps.
References Mao, Z., et al.: Tetrahedron Lett. 58, 4174 (2017)

Applications 2-Fluorobenzal Chloride is an important reagent in the synthesis of Benzenesulfonyl fluoride derivatives.
References Davies, W., et al.: J. Chem. Soc., 2042-2046 (1932)

Applications 1-bromo-2-(1,1-difluoroethyl)benzene (cas# 444581-46-8) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 5-Chloro-N-methyl-1H-indole-3-ethanamine is useful for the synthetic preparation of carbolinones.
References Han, H., et al.: J. Org. Chem., 84, 3357 (2019)

Applications 4-Bromo-2(3H)-benzoxazolone is a reagent used in the preparation of ceramidase Inhibitors.
References Bach, A., et al.: J. Med. Chem., 58, 9258-9272 (2015)