Halogenated Compounds

<p>Applications Chloromethyl Dimethylcarbamate is a useful realgent for synthesis in (Acyloxyalkyl)pyridinium salts as soluble prodrugs of a potent pyrrolothiazole platelet activating factor antagonist.<br>References Davidsen, S., et al.: J. Med. Chem., 37, 4423 (1994);<br></p>

<p>Applications 4-Chloronitrobenzene-13C6 is the labeled form of 4-Chloronitrobenzene(C373910). It is an intermediate in the synthesis of PCB 101-13C12 (P216628) which is a related compound of PCB 189-13C12(P216622), which is a flame retardant and a standard for environmental testing and research.<br>References EPA. Method 1668, (EPA 821-R-00-002) (1999)<br></p>

<p>Applications Copper (II) trifluoroacetate hydrate (cas# 123333-88-0) is a useful research chemical.<br></p>

<p>Applications (3-chlorophenyl)(phenyl)methanol (cas# 63012-03-3) is a useful research chemical.<br></p>

<p>Applications (1R-4S)-N-[4-chloro-5-(formylamino)-6-[[4-(hydroxymethyl)-2-cyclopenten-1-yl]amino]-2-pyrimidinyl]acetamide, is a precursor of (1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride (A603506), which is an intermediate for the synthesis of Abacavir (A105000) (1,2,3).<br>References (1) Daluge, S.M., et al.: Antimicrob. Ag. Chemother., 41, 1082 (1997) (2) Foster, R.H., et al.: Drugs, 55, 729 (1998) (3) Staszewski, S., et al.: J. Am. Med. Assoc., 285, 1155 (2001)<br></p>

<p>Applications 5-Chloro-3-[(methylamino)sulfonyl]-2-thiophenecarboxylic Acid is an intermediate in preparation of Lornoxicam.<br>References Fan, W., et al.: Zhon. Yiy. Gon. Zaz., 33, 365-366 (2002);<br></p>

<p>Applications 1,4-Diiodotetrafluorobenzene (cas# 392-57-4) is a reagent for synthesis of N-​aryl amides from O-protected hydroxamic acids.<br>References Broumidis, E., et al.: ChemPlusChem, 85, 1754 (2020)<br></p>

<p>Applications 2,6-Dibromo-4-cyanophenyl Heptanoate-d13 is a useful isotopically labeled compound<br></p>

<p>Applications 2-Iodo-5-methoxypyrazine is a reactant used in the preparation of substituted azaspiro[4.5]​decane derivatives with affinity to opioid receptors.<br>References Wegert, A. et al.: PCT Int. Appl. (2016), WO 2016008582 A1 20160121.<br></p>

<p>Applications 1-Bromohexane-5,5,6,6,6-d5 is a useful isotopically labeled compound of 1-Bromohexane (B683950)<br></p>

<p>Applications 1,1-Dichloroethylene-d2 (CAS# 22280-73-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications (1Z,1’Z)-Dimethyl-1,1’-(hydrazine-1,2-diylidene)bis(5-chloro-2-hydroxy-2,3-dihydro-1H-indene-2-carboxylate) is an intermediate in the synthesis of IN-KG 433 (I627995) which is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.<br>References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);<br></p>