Halogenated Compounds

<p>Applications 2-Iodo-5-methoxypyrazine is a reactant used in the preparation of substituted azaspiro[4.5]​decane derivatives with affinity to opioid receptors.<br>References Wegert, A. et al.: PCT Int. Appl. (2016), WO 2016008582 A1 20160121.<br></p>

<p>Applications 1-Bromohexane-5,5,6,6,6-d5 is a useful isotopically labeled compound of 1-Bromohexane (B683950)<br></p>

<p>Applications 1,1-Dichloroethylene-d2 (CAS# 22280-73-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications (1Z,1’Z)-Dimethyl-1,1’-(hydrazine-1,2-diylidene)bis(5-chloro-2-hydroxy-2,3-dihydro-1H-indene-2-carboxylate) is an intermediate in the synthesis of IN-KG 433 (I627995) which is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.<br>References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);<br></p>

<p>Applications 3,3,3-Trideuterio-2,2-difluoro-propanoic acid is a useful labeled building block.<br></p>

<p>Applications N1-(3-Aminopropyl)-N1-(2-bromoethyl)propane-1,3-diamine is a useful research chemical.<br></p>

<p>Applications 3-((5-Chloropyridin-2-yl)carbamoyl)pyrazin-2-yl)methyl 4-methylpiperazine-1-carboxylate is a useful synthesis intermediate.<br></p>

<p>Applications 2,3-Dichlorobenzenesulfonamide (cas# 82967-94-0) is a useful research chemical.<br></p>

<p>Applications 3,6-Dichloro-2-pyridinol can be used for various preparatory reactions, including photodegradations of chlorpyrifos in TiO2 suspensions.<br>References Sojic, D., et.al., J. Hazard. Mater., 168,94-101,(2009);<br></p>

<p>Applications 3,3-Difluorocyclopentanecarboxylic Acid is an intermediate in preparation of linked bisimidazoles, bisbenzimidazoles and analogs.<br>References Hewawasam, P., et al.: PCT Int. Appl. (2013), WO 2013106520 A1 20130718.<br></p>

<p>Applications (3R)-3-Fluoropyrrolidine-1-sulfonyl Chloride is used as a reagent in the preparation of heterocyclic compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides.<br>References Crew, A. P., et al.: PCT Int. Appl. 1014pp. (2018)<br></p>

<p>Applications 5-Bromo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid is a useful research chemical.<br></p>

<p>Applications 2,4,5-Trichlorophenacylidene Chloride is an intermediate in the synthesis of 2,4,5-Trichlorophenylethanediol (T382940); a metabolite of Tetrachlorvinphos (T292305). 2,4,5-Trichlorophenylethanediol is the byproduct of Tetrachlorvinphos being consumed by Dogs and Rats.<br>References Zhao, F., et al.: Anal. Bioanal. Chem., 408, 6423 (2016); Akintonwa,D., et al.: J Agr Food Chem., 15, 632-637 (1967)<br></p>

<p>Applications 2-(2-Bromoethoxy)Anisole (cas# 4463-59-6) is a useful research chemical.<br></p>

<p>Applications 2-(Chloromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one (CAS# 3166-54-9) is a useful research chemical compound.<br></p>

<p>Applications 2,2-Dibromo-1-cyclopropyl-2-(2-fluorophenyl)-ethanone is a useful research chemical.<br></p>

<p>Applications cis-3-Acetoxy-6-chlorocyclohexene is used as a reagent in the diastereoselective preparation of analogs of hydroxyoctahydroindolecarboxylates with 4,5- or 6,7-unsatturation using palladium-catalyzed allylations as key steps.<br>References Mao, Z., et al.: Tetrahedron Lett. 58, 4174 (2017)<br></p>

<p>Applications 2-Fluorobenzal Chloride is an important reagent in the synthesis of Benzenesulfonyl fluoride derivatives.<br>References Davies, W., et al.: J. Chem. Soc., 2042-2046 (1932)<br></p>

<p>Applications 1-bromo-2-(1,1-difluoroethyl)benzene (cas# 444581-46-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-Chloro-N-methyl-1H-indole-3-ethanamine is useful for the synthetic preparation of carbolinones.<br>References Han, H., et al.: J. Org. Chem., 84, 3357 (2019)<br></p>

<p>Applications 4-Bromo-2(3H)-benzoxazolone is a reagent used in the preparation of ceramidase Inhibitors.<br>References Bach, A., et al.: J. Med. Chem., 58, 9258-9272 (2015)<br></p>

<p>Applications Carboxylic Acids are used in preparation of Carboxylic acids via hydrocarboxylation/boration of alkenes/boronic acid pinacol esters with CO 2 using biomass-derived solvents.<br>References Gevorgyan, A., et al.: ChemSusChem, (2020);<br></p>

<p>Applications 2-Fluoro-3-nitrobenzoic Acid is used in preparation of bifunctional Heterocycles and their use in targeted degrdn. of RAF polypeptides.<br>References Crew, Andrew P., et al.: U.S. Pat. Appl. Publ., (2020);<br></p>

<p>Applications 2,6-Bis(trifluoromethyl)phenol is a useful intermediate for the preparation of tebufelone analogs.<br>References Miller, J. A., et al.: J. Org. Chem., 58, 2637 (1993)<br></p>

<p>Applications 2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one Hydrochloride is a salt of 2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one (C650415 ), used in the preparation of chalcone analogs containing a thieno[2,3-d]pyrimidin-2-yl groups with cytotoxic activity towards cultured human lung cancer A549 and colorectal HCT-116 cells.<br>References Wang, F., et al.: Bioorg. Chem., 94, 103346 (2020)<br></p>