Halogenated Compounds

<p>Applications 2-Fluorobenzyl alcohol (cas# 446-51-5) is a useful research chemical.<br></p>

<p>Applications Methyl 4-(3,3-dibromo-4-oxobutyl)benzoate is a reagent used in the preparation of 5-​substituted-​4,​6-​dioxo-​pyrrolo[2,​3-​d]​pyrimidines.<br>References Sekhar, N. et al.; Tetrahedron Lett., 52, 4140 (2011);<br></p>

<p>Applications α-Chloro-p-methyltoluene-13C is the labeled analogue of α-Chloro-p-methyltoluene(C369770). α-Chloro-p-methyltoluene is a building block that has been used as a reactant for the preparation of 6-aminoquinolone derivatives as submicromolar hepatitis C virus NS5B inhibitors<br>References Manfroni, G., et. al.: J. Med. Chem., Ahead of Print (2013)<br></p>

<p>Applications 1-Bromopentadecane-1-13C is a useful isotopically labeled compound of 1-Bromopentadecane (B686155)<br></p>

<p>Applications 2-(4-Fluorophenyl)-5-[(2-methylphenyl)methyl]thiophene is an intermediate for scalable and cost-effective optimized synthesis of Canagliflozin.<br>References Metil, D., et al.: Org. Process Res. Dev., 22, 27 (2018)<br></p>

<p>Applications N-​[4-​Cyano-​3-​(trifluoromethyl)​phenyl]​-​2-​hydroxy-​2-​methylpropanamide is a useful research chemical.<br></p>

<p>Applications 2-(3-Bromo-4-methoxyphenyl)-5,5-dimethyl-1,3-dioxane is an intermediate in the synthesis of VP 14637 (V785000), an inhibitor used to treat respiratory syncytial virus infections.<br>References Andries, K., et al.: Antiviral Res., 60, 209 (2003), Douglas, J., et al.: J. Virol., 77, 5054 (2003), Cianci, C., et al.: Antimicrob. Agents Chemother., 48, 413 (2004),<br></p>

<p>Applications α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-2-Naphthalenemethanamine Hydrochloride is an useful research chemical.<br></p>

<p>Applications N-(6-Bromo-4-hydroxyquinazolin-2-yl)guanidine (CAS# 74189-10-9) is a useful research chemical compound.<br></p>

<p>Applications 4-Chloro-2-ethyl-6-methylaniline is a reagent used in the synthesis of nanosized dendritic polyethylene.<br>References Yuan, J. et al.: Inorg. Chem. Acta., 400, 99 (2013);<br></p>

<p>Applications N-Desmethyl Trimipramine Chloroethylformate is an intermediate in the synthesis of N-Demethyl Trimipramine (D231350); a metabolite of Trimipramine (T799000).<br>References Zhang, J., et al.: Cancer Lett., 171, 153 (2001), Marella, M., et al.: J. Biol. Chem., 277, 25457 (2002), Llewelyn, C., et al.: Lancet, 363, 417 (2004),<br></p>

<p>Applications 1-(4-chlorophenoxy)-4-nitrobenzene (cas# 1836-74-4) is a useful research chemical.<br></p>

<p>Applications alpha,alpha'-Dibromo-p-xylene-d8 (CAS# 74903-77-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-(Trifluoromethyl)benzamide-D4 is an isotopic labeled intermediate for organic synthesis processes.<br></p>

<p>Applications 4-Bromo-5-methylpyridin-3-ol is a useful research chemical for organic synthesis.<br></p>

<p>Applications (2S)-2-Bromo-4-carbamoylbutanoic Acid is a useful research chemical.<br></p>

<p>Applications 6-(Bromomethyl)isobenzofuran-1(3H)-one is a useful research chemical for organic synthesis and other chemical processes.<br>References Neudeck, H. K., et al.: Monatsh. Chem., 127, 201 (1996); Nicolaou, K. C., et al.: J. Am. Chem. Soc., 138, 8235 (2016)<br></p>

<p>Applications 4-Bromo-2-methoxy-1-(methoxymethoxy) Benzene is an intermediate in the synthesis of Vanillactic Acid-13C3 (&gt;85%) (V097354) which is an isotope labelled compound of Vanillactic Acid (V097350). Vanillactic Acid is a metabolite of dihydroxyphenylalanine (DOPA) (D533751, L-DOPA), which is a natural isomer of the immediate precursor of dopamine.<br>References Tabar, et al.: Pharmacol. Biochem. Behav., 33, 139 (1989), De Souza Silva, et al.: J. Neurochem., 68, 233 (1997), Feigin, A., et al.: Neurology, 57, 2083 (2001),<br></p>

<p>Applications 3,4-Difluoro U-50488 Hydrochloride is a derivative of (+/-)-U-50488 Hydrochloride(U850328). (+/-)-U-50488 Hydrochloride is a selective κ-opioid agonist and an analgesic agent (1,2). (+/-)-U-50488 Hydrochloride can be used to analyze structure-​activity relationships of kappa opioid receptors.<br>References Von Voigtlander, P. et al.: Prog. Neuropsychopharmacol. Biol. Psychiatry., 6, 467 (1982); Jones, D. et al.: Biochem. Pharmacol., 80, 1478 (2010);<br></p>

<p>Applications 2-(Bromomethyl)-N,N-dimethyl-2-propenamide is used to prepare poly(cyclohexene oxide).<br>References Gupta, M., et al.: Polym. Bull., 62, 271 (2009);<br></p>

<p>Applications 3-(Trifluoromethyl)phenylhydrazine (cas# 368-78-5) is a useful research chemical.<br></p>