Ethers

<p>Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.<br>References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);<br></p>

<p>Applications Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is used in the preparation of dendronized polymers. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine can be used in the synthesis of optically degradable dendrons for temporary adhesion of proteins to DNA. It is also used in the preparation of tricylic polyamide receptor for carbohydrate recognition.<br>References Calderon, M. et al.: Macromol. Sym., 258, 53 (2007); Kostiainen, M.A. et al.: Chem. Eur. J., 16, 6912 (2010); Klein, E. et al.: Angew. Chem. Int. Ed., 44, 298 (2005);<br></p>

<p>Applications Bis[2-(2-chloroethoxy)ethyl] Ether, is an impurity in the synthesis of 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol (C365875), which is a polyethylene glycol used in the synthesis of novel glycolipids that bind HIV-1 cell surface glycoprotein Gp120 with potential application to pharmaceutical HIV-1 drugs. Also used in the synthesis of PET imaging agents targeting brain β-amyloid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References LaBell, R. et al.: Bioconj. Chem., 13, 143 (2002); Zhang, W. et al.: Nucl. Med. Biol., 32, 799 (2005);<br></p>

<p>Applications 3,4,5-Trimethoxyphenol is a useful synthetic intermediate in the synthesis of Thymonin (T413210); a flavonoid compound with potential antioxidant activity against peroxyl radicals.<br>References Dugas, A.J., et al.: J. Nat. Prod., 63, 327 (2000)<br></p>

<p>Applications 1-[3,4-Bis(phenylmethoxy)phenyl]ethanone is an intermediate in synthesizing Arbutamine (A766300). It is a cardiac stimulant. Arbutamine stimulates adrenergic receptors.<br>References Sinusas, A., et al.: J. Nucl. Med., 35, 664 (1994); Sansoy, V., et al.: Circulation, 92, 994 (1995); Elhendy, A., et al.: Eur. J. Nucl. Med., 23, 1354 (1996);<br></p>

<p>Stability Hygroscopic<br>Applications Ethyl 3,3-diethoxypropionate<br></p>

<p>Applications 2,3-Dimethoxyaniline (cas# 6299-67-8) is a useful research chemical.<br></p>

<p>Applications 3,5-Dimethoxyaniline (cas# 10272-07-8) is a compound useful in organic synthesis.<br></p>

<p>Applications (2R,​3S,​4S,​5S)-5-Hydroxy-2,3,4-tris(phenylmethoxy)-5-[(phenylmethoxy)methyl]-cyclohexanone was used in the synthetic preparation of N-substituted valiolamine derivatives.<br>References Fukase, H., et al.: J. Org. Chem., 57, 3642 (1992);<br></p>

<p>Applications Reagent used in Phthalimidooxy alylation.<br>References Yoda, R., et al.: Chem. Pharm. Bull., 42, 686 (1994), Kim, M., et al.: Bioorg. Med. Chem. Lett., 6, 2077 (1996),<br></p>

<p>Applications 3,3-Diethoxy-1-propanol is used as a reactant in the synthesis of nanoparticles.<br>References Sumitani, Shogo, et al.: Reactive &amp; Func. Polymers, 71(7), 684-693 (2011);Kanakubo, Yurie, et al.: Colloids and Surfaces, B, 78(1), 85-91 (2010)<br></p>

<p>Applications N10-(Ethoxycarbonyl)tryptamine is an intermediate in the synthesis of N-Methyltryptamine-d3 (M331922), which is a labeled N-Methyltryptamine, a N-monomethylated derivative of tryptamine. N-Methyltryptamine, unlike its unmethylated counterpart, does not produce any psychoactive effects. High levels of N-Methyltryptamine have been found in cisternal cerebrospinal fluid of patients with acute paranoid schizophrenia.<br>References Schmid, C. et al.: J. Neurosci., 30, 13513 (2010); Uebelhack, R. et al.: Biomed. Biochim. Acta, 42, 1343 (1983);<br></p>

<p>Applications 3,4-Bis(phenylmethoxy)-benzoic Acid is a useful synthetic intermediate. It is an intermediate used to synthesize Jaboticabin (J210370) which is minor bioactive depside potent to treat chronic obstructive pulmonary disease.<br>References Wu, S., et al.: J. Agri. Food Chem., 61, 4035 (2013); Reynertson, K., et al.: J. Nat. Prod., 69, 1228 (2006)<br></p>

<p>Applications 4,4'-Dimethoxydiphenylamine is a diphenylamine derivative used as a chemical additive for cured rubber. 4,4'-Dimethoxydiphenylamine is highly toxic and may potentially induce chromosome abberation.<br>References Kel'man, G.Y. et al.: Kauch. Rez., 26, 28 (1967); Sofuni, T. et al.: Mutat. res. Gen. Toxicol. Test., 24, 175 (1990);<br></p>

<p>Applications 2,4,5-TRIMETHOXYBENZOIC ACID (cas# 490-64-2) is a useful research chemical.<br></p>

<p>Applications 3,5-Dimethoxytoluene (cas# 4179-19-5) is a useful research chemical.<br></p>

<p>Applications 2-[2-(2-Propynyloxy)ethoxy]ethanol is a reactant used in the preparation of divalent ligands based on 3-deoxy-4-thiolactose as inhibitors of E. coli β-galactosidase.<br>References Cagnoni, A.J., et. al.: Org. Biomol. Chem., 11, 5500 (2013)<br></p>

<p>Applications 1,2,3-Trimethoxybenzene can be used for RSM-optimised slow pyrolysis of rice husk for bio-oil production.<br>References Das, S., et.al.: Energy, 225, 120161, (2021);<br></p>

<p>Applications 5-Bromo-2-ethoxy-benzenesulfonyl chloride<br></p>

<p>Applications 4,4-Dimethoxy-2-butanone is a reactant in the synthesis of naphthalimide-naphthyridine derivatives as a fluorescent probe for the detection of hydroxyl radicals in living cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Meng, L., et. al.: Chem. Commun., 50, 4843 (2014)<br></p>

<p>Applications Methyl 2-Acetyl-4,4-dimethoxybutanoate is a useful reagent for organic synthesis.<br>References Herrmann, J. L., et al.: Tetrahedron Lett., 47, 4711 (1973)<br></p>

<p>Applications 4,5-Dimethoxy-2-nitroaniline (cas# 7595-31-5) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications An intermediate for the preparation of (+/-)-Taxifolin.<br></p>

<p>Applications Tetramethoxypropane is a useful synthetic intermediate. It can be used to synthesize various compounds such as diiodonoradamantane and Salicylates[e.g. Salsalate(S095700)].<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ioannou, S., et al.: Tetrahedron Lett., 51, 2671 (2010); Sher, M., et al.: J. Org. Chem., 72, 6284 (2007)<br></p>

<p>Applications 2,2-Diethoxycycloheptanone is an intermediate in the synthesis of 1,2-Cycloheptanedione (C987255), a reagent in the synthesis of 3,3’-Polymethylene-2,2’-bibenzo[b]-1,10-phenanthrolines.<br>References Rahman, A. F. M., et al.: Heterocycles, 75, 871-877 (2008)<br></p>

<p>Applications 5-[3-(Trifluoromethoxy)phenyl-2-Furancarboxylic Acid is the structural analogue of 5-[2-(Trifluoromethoxy)phenyl]-2-furancarboxylic Acid (T790925), a reactant used in the preparation of (phenyl)-N-[(mercapto)(pyrrolyl)triazolyl]furancarboxamide and (phenoxy)-N-[(mercapto)(pyrrolyl)triazolyl]acetamide derivatives as herbicides.<br>References Xue, S., Lu, C.: Youji Huaxue, 28, 1083 (2008)<br></p>

<p>Applications Methyl Dimethoxyacetate is used as a reagent in the synthesis of benzimidazole derivatives for use as respiratory syncytial virus inhibitors.<br>References Cooymans, Ludwig Paul; D., et al. PCT Int. Appl. WO 2012080446 A1 20120621. Jun 21, 2012<br></p>

<p>Stability Hygroscopic<br>Applications [3-(3,4-dimethoxyphenyl)propyl](methyl)amine hydrochloride (cas# 83979-31-1) is a useful research chemical.<br></p>

<p>Applications Synthesis and receptor binding of 5-(amino[3H]2methyl)-3-isothiazolol ([3H]thiomuscimol), a specific GABAA agonist photoaffinity label.<br>References Frolund, B., et al.: J. Labelled Compounds Radiopharm., 36, 877 (1995),<br></p>

<p>Applications 5-[2-(Trifluoromethoxy)phenyl]-2-furancarboxylic Acid is a reactant used in the preparation of (phenyl)-N-[(mercapto)(pyrrolyl)triazolyl]furancarboxamide and (phenoxy)-N-[(mercapto)(pyrrolyl)triazolyl]acetamide derivatives as herbicides.<br>References Xue, S., Lu, C.: Youji Huaxue, 28, 1083 (2008)<br></p>

<p>Stability Hygroscopic<br>Applications Ethyl (Z)-[2-amino-4-thiazolyl](methoxyimino)acetate is used in the preparation of ceftriaxone-d3 (C245002), which is a labelled antibacterial.<br>References Reiner, R., et al.: J. Antibiot., 33, 783 (1980)<br></p>

<p>Stability Moisture Sensitive<br>Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.<br>References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);<br></p>

<p>Applications 2-(4-Amino-2-ethoxyphenyl)pthalimide (cas# 106981-52-6) is a compound useful in organic synthesis.<br></p>

<p>Stability Volatile<br>Applications Methoxytrimethylsilane (cas# 1825-61-2) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (E)-1,1-Dimethoxybut-2-ene is a useful research chemical for organic synthesis and other chemical processes.<br>References Huot, J. F., et al.: Chem. Lett., 9, 1599 (1991); Mathew, S., et al.: Process Biochem., 501985 (2015)<br></p>

<p>Applications (6,7-dimethoxy-4-oxoquinazolin-3(4H)-yl)acetic acid (cas# 877140-09-5) is a useful research chemical.<br></p>

<p>Applications Methyl 2-Acetamido-2-(Dimethoxyphosphoryl)Acetate (cas# 89524-99-2) is a useful research chemical.<br></p>

<p>Applications ETHYL 4-ETHOXYBENZOATE (cas# 23676-09-7) is a useful research chemical.<br></p>

<p>Applications 3-(2-Aminoethoxy)propionic Acid (cas# 144942-89-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-3-oxobutanoate is an intermediate for the synthesis of O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine (D289480), which is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions.<br>References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995)<br></p>

<p>Applications 4,5-Dimethoxy-2-nitrobenzoic Acid (cas# 4998-07-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl 4-(trifluoromethoxy)benzoate<br></p>

<p>Applications 3,4-Dimethoxybenzylamine (cas# 5763-61-1) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-(Dimethoxyphosphoryl)acetic acid<br></p>

<p>Applications 2-(1,1-Dimethylethoxy)-1-propanol is a useful reagent for organic synthesis.<br></p>

<p>Applications 5-(Ethoxycarbonyl)thiophene-3-boronic Acid is a useful reagent for preparing hydroxyimino(phenyl)propanones as GPBAR1 agonists.<br>References Bissantz, C., et al.: U.S. Pat. Appl. Publ. (2012), US 20120010190 A1<br></p>

<p>Applications N-[[4-(Phenylmethoxy)phenyl]methyl]-2-[(3-thienylcarbonyl)amino]-4-thiazoleacetamide is derived from ethyl 2-amino-4-thiaxolacetate (E899330) which is used in the synthesis of various pharmaceutical and biologically active compounds including inhibitors and antibiotics.<br>References Inamoto, Y., et al.: J. Antibiot., 41, 828 (1988)<br></p>

<p>Applications Diethyl 3,5-Dimethoxybenzylphosphonate (cas# 108957-75-1) is a compound useful in organic synthesis.<br></p>

<p>Applications A useful wittig reagent.<br></p>

<p>Applications 2,5-dimethoxycyclohexa-2,5-diene-1,4-dione (cas# 3117-03-1) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br></p>

<p>Applications An intermediate for the preparation of Terbutaline.<br></p>

<p>Applications 4,4'-Dimethoxybenzhydrol acts as a reagent in the preparation of aryloxyacetamide derivatives and their biological activity as neuroprotective agents. Preparation and anticancer activity of quebecol and analogs.<br>References Zhong, Y., et al.: Bioorg. Med. Chem. Lett., 26, 2526 (2016); Pericherla, K., et al.: Bioorg. Med. Chem. Lett., 23, 5329 (2013)<br></p>

<p>Applications 4,4-Diethoxy-N,N-diethyl-1-butanamine is a useful reagent for the synthesis of amino acetals.<br>References Keglevic, D., et al.: Croat. Chem. Acta, 35, 175(1963)<br></p>

<p>Applications 4,4-Dimethoxybutan-1-ol is a reactant used in the preparation of tetrahydropyranols and hydropyranooxepans.<br>References Hoffmann, R.W., et. al.: New J. Chem., 25, 102 (2001)<br></p>

<p>Stability Light Sensitive<br>Applications Cis-1-Bromo-2-ethoxyethylene<br></p>

<p>Impurity Lubiprostone Impurity VI<br>Applications 7-((1R,2R,3R)-3-(cyclohexylmethoxy)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl)heptanoic Acid is a useful chemical reagent.<br></p>

<p>Applications Methyl Methoxyacetate is a reagent used in the synthesis of diphenylamine-terepthalaldehyde resins which maybe be used as a catalyst for tetrahydropyranylation.<br>References Tanemura, K. et al.: Org. Prep. Proc. Int., 48, 72 (2016); By: Robiette, R. et al.: J. Am. Chem. Soc., 138, 737 (2016);<br></p>

<p>Stability Store at -20°C under Argon. Air Sensitive.<br>Applications 5,5-Diethoxypentanal (cas# 79893-96-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,4'-Dimethoxystilbene is an intermediate in the synthesis of nonsteroidal, selective estrogen receptor modulator (SERM), Raloxifene (R100000).<br>References Liu, H., et al.: Chem. Res. Toxicol., 18, 162 (2005); Chen, Z., et al.: J. Org. Chem., 65, 8811 (2000);<br></p>

<p>Applications o-Carbomethoxybenzyl Sulfonamide is a useful reactant in organic synthesis.<br>References Jiang, Lin, et al.: Youji Huaxue, 26(2), 203-206 (2006)<br></p>

<p>Applications Methyl 5-Chloro-2-[(4-ethoxy-4-oxobutyl)amino]benzoate is a reactant in the synthesis of 7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzoazepin, an intermediate in synthesis of Tolvaptan (T536650).<br>References Liu, Dengke, et al.: Tianjin Institute of Pharmaceutical Research, CN 103012265 A 20130403(2013);<br></p>

<p>Applications 1-[2-Hydroxy-4,6-bis(ethoxymethoxy)phenyl]ethanone (cas# 128837-25-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,4-Dimethoxybenzene is a useful chemical in organic synthesis.<br>References Digwal, Chander S., et al.: Asian J. of Org. Chem., 7(5), 865-869 (2018);Cai, Zhi-Bin, et al.: RSC Advances, 6(52), 46853-46863 (2016);Lin, Qi, et al.: Soft Matter, 13(39), 7222-7226 (2017)<br></p>

<p>Applications 3,5-Dimethoxybenzyl Alcohol is used in the synthesis of Resveratrol (R150000).<br></p>