Amides

<p>Please enquire for more information about GLP-1 (1-36) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (D-Ala2)-GRF (1-29) amide (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PAR-2 agonist is a synthetic peptide that activates PAR-2. It binds to PAR-2 receptors, which are present in the mesenteric vasculature and in various other tissues. Activation of PAR-2 leads to an increase in intracellular calcium concentration, activation of protein kinase C, cytosolic calcium ion release, phosphorylation of myosin light chain, muscle cell proliferation, transcription and translation initiation, and increased production of vasoactive intestinal peptide. This drug also has anti-inflammatory effects and stimulates epidermal growth factor (EGF) and thrombin receptor expression as well as growth factor production.</p>

<p>Please enquire for more information about Phenyl-(2-pyridyl)acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about PAR-4 (1-6) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methylsalicylamide is a chemical compound that belongs to the class of isonicotinic amides. It is a potent anti-inflammatory agent with minimal inhibitory concentration (MIC) values of 4 µg/mL for gram-positive bacteria and 8 µg/mL for gram-negative bacteria. This compound has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. 4-Methylsalicylamide has been shown to have an inhibitory effect on ring-opening, which may be due to its ability to acetylate mitochondrial membranes, altering the membrane potential. The molecular modeling studies also showed that 4MSAM binds at the same site as antibiotics such as penicillin and erythromycin in bacterial ribos</p>

<p>2-Aminoethanesulphonamide monohydrochloride is a perovskite with a hexagonal shape. It has been shown to interact with the pharmacophore of the enzyme cytochrome P450, and it has been optimized for the reaction by altering its structure. This product is soluble in gaseous form, but can also be used as a solid. 2-Aminoethanesulphonamide monohydrochloride has an absorption maximum at 325 nm and emits fluorescence at 420 nm. It is used in devices that detect ionizing radiation.</p>

<p>Please enquire for more information about Amyloid P Component (27-38) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>pTH (1-31) amide is a polymer conjugate that is used to treat osteoporosis. It has been shown to be effective in reducing the risk of fracture and increasing bone mineral density in animals. The compound binds to the extracellular domain of the estrogen receptor, altering its conformation and preventing it from interacting with other proteins in the nucleus. pTH (1-31) amide has also been shown to reduce blood pressure in animals by inhibiting angiotensin-converting enzyme. Clinical data on this drug are limited, but it has been well tolerated so far.</p>

<p>Please enquire for more information about (Nle 8·18,Tyr34)-pTH (3-34) amide (bovine) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-Acetyl-L-norleucyl-L-glutaminyl-L-histidyl-D-phenylalanyl-L-arginyl-D-tryptophylglycinamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about GLP-1 (7-36)-Lys(6-FAM) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Syndyphalin SD-33 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Beta-casomorphin (1-3) amide acetate salt (BCMA) is a peptide that belongs to the class of opioid compounds. It is an amino acid and has been shown to be a potent agonist at opioid receptors. BCMA is used in vivo as a tritiated ligand for mapping the distribution of opioid receptors in rat brain. The affinity of BCMA for opioid receptors increases with dose, and its antinociceptive effects are dose-dependent. Beta-casomorphin (1-3) amide acetate salt has also been shown to have affinity for enkephalins, which are naturally occurring peptides that bind to opioid receptors.</p>

<p>Salicylamide is a drug that is used as an analgesic, antipyretic, and anti-inflammatory agent. It is also used to treat bowel disease, including ulcerative colitis and Crohn's disease. Salicylamide has been shown to inhibit the activity of enzymes such as cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), which are responsible for the production of inflammatory mediators. Salicylamide also inhibits copper chloride induced synchronous fluorescence in rat colon cells. Salicylamide also binds to human serum albumin and other nitrogen atoms, which can be measured using chemiluminescence methods. Salicylamide may also have properties that make it useful for the detection of cancerous tumors in the colon. Salicylamide can be detected using electrochemical impedance spectroscopy by measuring its resistance at different frequencies when a voltage is applied across a cell containing sal</p>

<p>Benzamidine is a benzamidase inhibitor that competitively binds to bacterial enzymes such as metalloendopeptidases and matrix metalloproteinases. It inhibits the degradation of collagen, resulting in a higher concentration of soluble extract. This drug also has an effect on spermatozoa, which may be due to its ability to inhibit bacterial enzymes that are involved with uptake and preload. Benzamidine has been shown to have a pH optimum of 8-9 and is most active at this pH range.</p>

<p>PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt is a guanine nucleotide binding protein that belongs to the PAR family of proteins. It is expressed in wild type mice and binds to the cytosolic calcium, which regulates polymerase chain reaction. PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe NH2 trifluoroacetate salt can be used as a potential drug target for epidermal growth factor. It has been shown to activate transcription polymerase chain and transcriptase polymerase chain during transcriptional regulation of messenger RNA.</p>

<p>Please enquire for more information about PAR-3 (1-6) amide (mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Cecropin A (1-8)-Melittin (1-18) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Propionyl-Amyloid b-Protein (31-34) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Levomilnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used for the treatment of major depressive disorder and fibromyalgia. It has been shown to have antidepressant effects in patients with major depressive disorder and fibromyalgia. Levomilnacipran inhibits the reuptake of serotonin and norepinephrine by blocking the transporter proteins in these neurotransmitter pathways, increasing their availability to interact with receptors in the brain. Levomilnacipran also has been found to inhibit aminotransferase activity, which may be responsible for its hepatotoxicity.</p>

<p>4-Bromo-2-fluoro-N-methylbenzamide is an impurity in the pharmaceutical drug nilutamide. It is a ligand that binds to the androgen receptor and inhibits the binding of dihydrotestosterone, reducing its effect on prostate cells. 4-Bromo-2-fluoro-N-methylbenzamide has been shown to have pharmacokinetic properties similar to nilutamide, which is a drug used for treating prostate cancer. This impurity is also found in small quantities in other drugs including cyclobutanone, 2-aminoisobutyric acid, and chloral hydrate. The elucidation of these impurities can help regulate the quality of pharmaceutical drugs.</p>

<p>Antho-RFamide Pyr-Gly-Arg-Phe-NH2 is an acidic amino acid. It has been shown to be a precursor of dopamine β-hydroxylase, which is a key enzyme in the synthesis of epinephrine and norepinephrine. This compound has a diameter of 0.8 nm, and it's been observed in cnidarians and multicellular animals. The biological function of Antho-RFamide Pyr-Gly-Arg-Phe-NH2 is not yet known, but it has been sequenced and identified as fatty acid with a sequence that is identical to serotonin. Analysis shows that this molecule contains an acidic environment with an alkaline pH.</p>

<p>2,2-Dimethylpropionamide is a synthetic chemical that has been shown to have cytotoxic and biochemical properties. It has been tested on leukemia cells (K562) and has been shown to inhibit the bcr-abl kinase. 2,2-Dimethylpropionamide has also been shown to inhibit the production of amide radicals in human serum under constant pressure. The structure of this compound was solved using X-ray diffraction data.</p>

<p>Tenofovir alafenamide (free base) is a prodrug of tenofovir with action on viral reverse transcriptase to block replication and is used for treating HIV/AIDS and chronic hepatitis B with improved safety profile.</p>

<p>L-trans-Epoxysuccinyl-Ile-Pro-OMe propylamide is a pharmacological agent that inhibits the toll-like receptor 4 signaling pathway. L-trans-Epoxysuccinyl-Ile-Pro-OMe propylamide has been shown to cause caspase independent cell death by inducing cathepsin and iron homeostasis. The drug also causes polymerase chain reaction inhibition and neuronal death in vivo.</p>

<p>tert-Butylsulfinamide is a model system for the synthesis of enantiopure amines and esters. The synthesis of tert-butylsulfinamide starts with the reaction of an allyl bromide with a sulfinic acid chloride to form an allyl sulfonate, which is then hydrolyzed to produce tert-butylsulfinamide. The yield for this type of reaction is usually low, but tert-butylsulfinamide can be isolated in good yields if it is prepared in a stereoselective manner. Tert-butylsulfinamide has been shown to inhibit the growth of human hair follicles in cell culture experiments, which may be due to its ability to inhibit the formation of hydrogen peroxide by inhibiting an enzyme called tyrosine hydroxylase.</p>

<p>Cefpiramide sodium is a cephalosporin antibiotic that has been shown to be effective against a wide range of bacteria, including those which are resistant to other antibiotics. Cefpiramide sodium is used for the treatment of skin and soft tissue infections in infants or for the treatment of respiratory tract infections in adults. The antibiotic binds to bacterial cell membranes and inhibits bacterial growth by inhibiting fatty acid synthesis, which is important for the production of cell walls. Cefpiramide sodium has been shown to have antiviral properties as well as antibacterial properties. These effects may be due to its ability to inhibit viral protein synthesis or by binding directly to the virus itself. Cefpiramide Sodium is an anti-infective drug that belongs to a group called cephalosporins, which are antibiotics that inhibit growth of bacteria by binding to their cell walls and preventing them from synthesizing essential fatty acids required for building their cell walls. It also has antiviral properties.</p>

<p>6-Ethoxy-2-benzothiazolesulfonamide is a drug that inhibits carbonic anhydrase, which is an enzyme that catalyzes the conversion of carbon dioxide and water to bicarbonate and hydrogen ions. This drug has been shown to be effective for the treatment of bowel disease in animal models. 6-Ethoxy-2-benzothiazolesulfonamide has also been shown to have inhibitory properties against carbonic anhydrase, which may lead to problems with dehydration.</p>

<p>Please enquire for more information about N-[5-[5-(2-Methyl-1-oxoisoindolin-5-yl)thien-2-yl]pyridin-3-yl]-2-nitrobenzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sieber Amide Resin is a glycopeptide that has been shown to inhibit the growth of prostate cancer cells. It inhibits the production of epidermal growth factor and amide, serine protease, and growth factors by binding to their receptors on the cell surface. This drug also has antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus, Streptococcus pyogenes, and Bacillus subtilis. The chemical diversity of Sieber Amide Resin allows it to be used as an intermediate in the synthesis of other pharmaceutically active compounds. The pharmacokinetic properties of this drug allow it to be administered orally or intravenously. The nmr spectra show that this drug is a cyclic peptide with an amide bond between amino acid residues Ser-11 and Gly-12.</p>

<p>Please enquire for more information about N-(3-Aminopropyl)-2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Benzenesulfonamide,3-hydrazino- including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Isoleucine beta-naphthylamide is an amide derivative of L-isoleucine and 2-naphthylamine, which are carboxylic acid derivatives. The condensation of these two substances leads to the formation of a new compound with a carboxy group and an amino group.</p>

<p>N-(5-Aminopentyl) methotrexate amide-LC-biotin is a specialized bioconjugate, derived through the conjugation of methotrexate, an established antifolate drug, with an LC-biotin moiety. This product is synthesized by covalently linking methotrexate, which is known for its role in cancer therapy through the inhibition of dihydrofolate reductase (DHFR), to a biotin moiety via a long-chain spacer. The resultant bioconjugate retains the therapeutic effects of methotrexate, particularly in its ability to interrupt nucleotide synthesis, thereby affecting cell division in rapidly proliferating cancer cells.The inclusion of biotin in the structure allows for facile attachment to avidin or streptavidin-labeled systems, facilitating targeted delivery and enhanced detection in molecular and cellular studies. The primary application of N-(5-Aminopentyl) methotrexate amide-LC-biotin lies in the realm of targeted drug delivery and advanced research into methotrexate metabolism. By leveraging the high affinity of biotin-streptavidin interactions, researchers can effectively study the biodistribution and cellular uptake of methotrexate, advancing cancer therapeutic strategies and providing insights into antifolate drug mechanisms at the molecular level.</p>

<p>Dithiooxamide is a chemical compound that contains two sulfur atoms, one oxygen atom, and one nitrogen atom. It has been shown to be an effective treatment for wastewater by removing nitrogen and phosphorus. Dithiooxamide binds to metal ions such as copper and iron in the water, forming a complex. This process prevents the metal ions from being available as catalysts in the oxidation of organic pollutants. The binding of dithiooxamide with these metals also removes them from wastewater, preventing them from being taken up by plants or animals. Dithiooxamide can be used to remove malonic acid (a carcinogen) and p-nitrophenyl phosphate (a liver toxin) from blood samples for analysis using electrochemical impedance spectroscopy, which relies on the ability of dithiooxamide to bind to these chemicals. Dithiooxamide is also used as a surfactant in analytical chemistry methods such as gas chromatography or liquid chromatography because it</p>

<p>Please enquire for more information about 3-(Aminomethyl)-N,N-dimethyl-1,2,4-oxadiazole-5-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N,N-Dimethylformamide dineopentyl acetal (DMFD) is a synthetic drug that has been used to treat cancer and infectious diseases. It is synthesized from the reaction of dimethylformamide with diethylacetal. DMFD has shown an anti-inflammatory effect in animals, which may be due to its ability to inhibit the production of prostaglandins. The structural analysis of DMFD reveals the presence of two phenyl groups and a hydroxyl group, which are responsible for its biological activity. Structural analysis also led to the determination of several functional groups, including a chloride ion and a methoxy group.</p>

<p>Please enquire for more information about Gly-arg-4-methoxy-beta-naphthylamide dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>NIR-664 is a potential use for the treatment of cancer. It is an iodinated acetamide with a ruthenium complex that has been shown to have magnetic and fluorescent properties. The diameter of NIR-664 is approximately 2 nm, and it has a hydrophobic character. This compound can be used in nanocrystals or as a mesoporous material. The fluorescence of NIR-664 can be observed in the near infrared region at 664 nm, which gives this compound its name. NIR-664 has also been shown to react with ruthenium, which makes it suitable for use in particle form.</p>

<p>N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide is a novel glycol ester with cytotoxic effects. It has been shown to inhibit the growth of cancer cells in rat liver microsomes and in vivo. N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide inhibits the synthesis of fatty acids by inhibiting the enzyme lipoxygenase. This drug also has a reactive carbon nanotube that may be used as an anticancer agent, which can bind to cell membranes and disrupt their function.</p>

<p>Please enquire for more information about N-Propyl-N-(2,3-epoxypropyl)perfluoro-n-octylsulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Glucagon-like peptide 1 (7-36) amide is a peptide hormone produced by the ileum and colon of the small intestine in response to food intake. It stimulates insulin release from the pancreas, inhibits glucagon secretion, and slows gastric emptying. GLP-1 is also a potent regulator of glucose homeostasis. The GLP-1 analogues are used for treatment of type 2 diabetes mellitus. These analogues are either injected or taken orally and mimic the effect of natural GLP-1 on blood sugar regulation and appetite control. The long duration of action means that daily injections or multiple oral doses are required to maintain therapeutic levels.</p>