Amides

<p>Galanin (2-11) amide trifluoroacetate salt H-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu is a galanin analog and a ligand for the galanin receptor 1. It has affinity for the receptors in the brain, which are involved in cognition, and is used to study Alzheimer's disease. Galanin (2-11) amide trifluoroacetate salt H-Trp-Thr-Leu-Asn-Ser -Ala -Gly -Tyr -Leu -Leu is a member of the family of neuropeptides and neuromodulators that regulate nerve injury and alzheimer's disease.</p>

<p>Nalpha-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide is a chemical compound that inhibits the activity of proteases. It has been shown to inhibit leukemia cells and actinomycetes. This chemical binds to the active site of proteases, inhibiting the hydrolysis of peptides by blocking the access of water molecules to the reactive site. In addition, Nalpha-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide can also be used as a fluorescent probe for protease activity in analytical methods. The product research on this compound has shown that it is a potent inhibitor of cyclic peptide synthetases and can be used as an anti-inflammatory agent.</p>

<p>Please enquire for more information about Mca-Amyloid beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide is a carboxamide analog of dibucaine. It is synthesized from chloroacetyl chloride and isatin in the presence of sodium hydroxide. The synthesis has been scaled to an industrial level. 2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide has been shown to have analgesic properties, similar to those of dibucaine. Radiolysis of this compound gives a carboxylic acid and a heterocyclic ring product.</p>

<p>4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4AFBDS) is a chemical compound that can be used for the treatment of wastewater. It has shown to be effective against anhydrase, which is an enzyme that catalyzes the conversion of water to hydrogen peroxide and hydroxide ion. 4AFBDS also attenuates oxidative stress in cardiac cells and inhibits the production of active oxygen species by inhibiting the activity of carbonic anhydrase. The chromatographic method used to detect 4AFBDS was found to be more sensitive than a standard colorimetric assay, making it a better tool for detecting this compound in wastewater samples. br&gt; br&gt; br&gt; br&gt; br&gt; This compound has been shown to have inhibitory effects on e3 ubiquitin ligase, which plays a role in protein degradation via aut</p>

<p>Please enquire for more information about Acetyl-Neurotrophin Receptor (368-381) amide (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Galanin (1-13)-Neuropeptide Y (25-36) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about HSV-1-amide UL 26 Open Reading Frame (242-255) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Amyloid b-Protein (1-40) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Intermediate in the synthesis of vildagliptin</p>

<p>Intermediate in the synthesis of lenvatinib</p>

<p>N,N'-Methylenediacrylamide is a water-soluble compound that has been used as a fluorescent probe for hydrogen bonding. It has been shown to have different phase transition temperatures in different solvents and can be used as an experimental model for studying the effects of temperature on the behavior of water molecules. N,N'-Methylenediacrylamide reacts with hydrochloric acid to form the fatty acid N,N'-methylenebis(3-chloroacrylic acid) under acidic conditions. This reaction is reversible, and the reverse process can be catalyzed by sodium citrate or human serum. When exposed to radiation or surface methodology, it emits light at a wavelength of 350 nm.</p>

<p>Please enquire for more information about pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-(2-Amino-ethyl)-2-(benzyl-phenyl-amino)-acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2R)-2-Aminopropanamide is a chemical compound that is classified as an amide. It has been shown to inhibit bacterial growth and induce apoptosis in mammalian cells, but not in bacteria. This drug has a number of hydrogen bonding interactions with the carbonyl group and amide functional groups and can bind to affinity ligands with hydrogen bonding interactions. (2R)-2-Aminopropanamide inhibits the activity of enzymes that are involved in the synthesis of d-alanine, which is a precursor for protein synthesis. It also inhibits the enzyme glutamine synthase, which plays a key role in building up nitrogen reserves in bacteria. The drug binds to DNA by forming hydrogen bonds with the phosphate backbone and intercalates into double-stranded DNA by forming van der Waals interactions with base pairs.</p>

<p>Please enquire for more information about N-Acetyl-L-norleucyl-L-glutaminyl-L-histidyl-D-phenylalanyl-L-arginyl-D-tryptophylglycinamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Leu-Enkephalin amide acetate salt H-Tyr-Gly-Gly-Phe-Leu-NH2 acetate salt is a peptide that is used as an analgesic and antipyretic drug. It is a synthetic form of endogenous enkephalins, which are natural pain relievers. The chemical stability of Leu-Enkephalin amide acetate salt H-Tyr-Gly-Gly-Phe-Leu-NH2 acetate salt makes it an effective drug for chronic use, and it has been shown to have a low side effect profile. This compound also has been shown to block the synthesis of histamine in vivo, but its bioavailability in vivo is not high due to its rapid degradation by proteases.</p>

<p>6-Aminopicolinamide is a metabolite of nicotinamide, which can be found in the urine of humans and animals. 6-Aminopicolinamide has been shown to have anti-leukemic activity against experimental leukemias in animals. The mechanism of action is not well understood but may involve inhibition of nucleotide synthesis or the inhibition of dehydrogenase activity. Clinical trials are underway to determine its efficacy as an anti-tumor agent.</p>

<p>2-Amino-5-chloro-N,3-dimethylbenzamide is a synthetic compound. It has been shown to induce necrotic cell death in mammalian cells. This compound was synthesized by the reaction of 2-aminoquinoline with a Grignard reagent, followed by nitration of the resultant amine. The synthesis of this compound was thermodynamically favorable and exhibited good solubility in water. The chlorantraniliprole and anthranilic acid moieties are activated with an acylation reaction, which allows them to bind to the ryanodine receptor and inhibit calcium release from the sarcoplasmic reticulum (SR) with ammonolysis. This inhibition leads to ferroptosis, a type of programmed necrosis.</p>

<p>Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a peptide that was generated by incubating β-amyloid with the protease papain. This peptide has been shown to induce population and biochemical changes in cells, including focusing of β-amyloid aggregates. It also induces reactive oxygen species and promotes extracellular protofibril formation. Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a conjugate of acetylated lysine residues and amyloid β-protein that can be used as an anti-amyloid therapeutic. The peptide is characterized by dichroism spectroscopy, which has revealed its specific binding to the fibrils' surface.</p>

<p>Please enquire for more information about Big Endothelin-3 (22-41) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt is a guanine nucleotide binding protein that belongs to the PAR family of proteins. It is expressed in wild type mice and binds to the cytosolic calcium, which regulates polymerase chain reaction. PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe NH2 trifluoroacetate salt can be used as a potential drug target for epidermal growth factor. It has been shown to activate transcription polymerase chain and transcriptase polymerase chain during transcriptional regulation of messenger RNA.</p>

<p>Please enquire for more information about (Deamino-Cys11,D-2-Nal 14,Cys18)-b-MSH (11-22) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Salicylamide is a drug that is used as an analgesic, antipyretic, and anti-inflammatory agent. It is also used to treat bowel disease, including ulcerative colitis and Crohn's disease. Salicylamide has been shown to inhibit the activity of enzymes such as cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), which are responsible for the production of inflammatory mediators. Salicylamide also inhibits copper chloride induced synchronous fluorescence in rat colon cells. Salicylamide also binds to human serum albumin and other nitrogen atoms, which can be measured using chemiluminescence methods. Salicylamide may also have properties that make it useful for the detection of cancerous tumors in the colon. Salicylamide can be detected using electrochemical impedance spectroscopy by measuring its resistance at different frequencies when a voltage is applied across a cell containing sal</p>

<p>Dermorphin is a neuropeptide that has been shown to reduce cortisol levels in badgers and has been shown to have biological activity in vitro. Dermorphin also has a number of pharmacokinetic properties, including water solubility, lipid solubility, and oral bioavailability. The drug binds to δ receptors and inhibits the enzyme activities of rat liver microsomes. Dermorphin is used as an analgesic for bowel disease, such as inflammatory bowel disease or hypogaea. Dermorphin has antinociceptive properties (pain-relieving).</p>

<p>Glycinamide hydrochloride is an inhibitor that binds to the glycine-binding site of the protein synthetase and inhibits the formation of glycinamide ribonucleotide. It has been shown to inhibit human glycinamide ribonucleotide synthetase in vitro. Glycinamide hydrochloride is also a glycinamide amide, which was synthesized by linking two molecules of glycine with an amide bond. This molecule is cross-linked with a macrogel, forming a hydrogel. The hydrogel can be used in biomedical applications, such as tissue engineering and drug delivery systems.</p>

<p>Please enquire for more information about N-(3-Aminopropyl)-2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-[5-[5-(2-Methyl-1-oxoisoindolin-5-yl)thien-2-yl]pyridin-3-yl]-2-nitrobenzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sieber Amide Resin is a glycopeptide that has been shown to inhibit the growth of prostate cancer cells. It inhibits the production of epidermal growth factor and amide, serine protease, and growth factors by binding to their receptors on the cell surface. This drug also has antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus, Streptococcus pyogenes, and Bacillus subtilis. The chemical diversity of Sieber Amide Resin allows it to be used as an intermediate in the synthesis of other pharmaceutically active compounds. The pharmacokinetic properties of this drug allow it to be administered orally or intravenously. The nmr spectra show that this drug is a cyclic peptide with an amide bond between amino acid residues Ser-11 and Gly-12.</p>

<p>Cefpiramide sodium is a cephalosporin antibiotic that has been shown to be effective against a wide range of bacteria, including those which are resistant to other antibiotics. Cefpiramide sodium is used for the treatment of skin and soft tissue infections in infants or for the treatment of respiratory tract infections in adults. The antibiotic binds to bacterial cell membranes and inhibits bacterial growth by inhibiting fatty acid synthesis, which is important for the production of cell walls. Cefpiramide sodium has been shown to have antiviral properties as well as antibacterial properties. These effects may be due to its ability to inhibit viral protein synthesis or by binding directly to the virus itself. Cefpiramide Sodium is an anti-infective drug that belongs to a group called cephalosporins, which are antibiotics that inhibit growth of bacteria by binding to their cell walls and preventing them from synthesizing essential fatty acids required for building their cell walls. It also has antiviral properties.</p>

<p>tert-Butylsulfinamide is a model system for the synthesis of enantiopure amines and esters. The synthesis of tert-butylsulfinamide starts with the reaction of an allyl bromide with a sulfinic acid chloride to form an allyl sulfonate, which is then hydrolyzed to produce tert-butylsulfinamide. The yield for this type of reaction is usually low, but tert-butylsulfinamide can be isolated in good yields if it is prepared in a stereoselective manner. Tert-butylsulfinamide has been shown to inhibit the growth of human hair follicles in cell culture experiments, which may be due to its ability to inhibit the formation of hydrogen peroxide by inhibiting an enzyme called tyrosine hydroxylase.</p>

<p>6-Ethoxy-2-benzothiazolesulfonamide is a drug that inhibits carbonic anhydrase, which is an enzyme that catalyzes the conversion of carbon dioxide and water to bicarbonate and hydrogen ions. This drug has been shown to be effective for the treatment of bowel disease in animal models. 6-Ethoxy-2-benzothiazolesulfonamide has also been shown to have inhibitory properties against carbonic anhydrase, which may lead to problems with dehydration.</p>

<p>L-Isoleucine beta-naphthylamide is an amide derivative of L-isoleucine and 2-naphthylamine, which are carboxylic acid derivatives. The condensation of these two substances leads to the formation of a new compound with a carboxy group and an amino group.</p>

<p>Please enquire for more information about Benzenesulfonamide,3-hydrazino- including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(5-Aminopentyl) methotrexate amide-LC-biotin is a specialized bioconjugate, derived through the conjugation of methotrexate, an established antifolate drug, with an LC-biotin moiety. This product is synthesized by covalently linking methotrexate, which is known for its role in cancer therapy through the inhibition of dihydrofolate reductase (DHFR), to a biotin moiety via a long-chain spacer. The resultant bioconjugate retains the therapeutic effects of methotrexate, particularly in its ability to interrupt nucleotide synthesis, thereby affecting cell division in rapidly proliferating cancer cells.The inclusion of biotin in the structure allows for facile attachment to avidin or streptavidin-labeled systems, facilitating targeted delivery and enhanced detection in molecular and cellular studies. The primary application of N-(5-Aminopentyl) methotrexate amide-LC-biotin lies in the realm of targeted drug delivery and advanced research into methotrexate metabolism. By leveraging the high affinity of biotin-streptavidin interactions, researchers can effectively study the biodistribution and cellular uptake of methotrexate, advancing cancer therapeutic strategies and providing insights into antifolate drug mechanisms at the molecular level.</p>

<p>N,N-Dimethylformamide dineopentyl acetal (DMFD) is a synthetic drug that has been used to treat cancer and infectious diseases. It is synthesized from the reaction of dimethylformamide with diethylacetal. DMFD has shown an anti-inflammatory effect in animals, which may be due to its ability to inhibit the production of prostaglandins. The structural analysis of DMFD reveals the presence of two phenyl groups and a hydroxyl group, which are responsible for its biological activity. Structural analysis also led to the determination of several functional groups, including a chloride ion and a methoxy group.</p>

<p>Dithiooxamide is a chemical compound that contains two sulfur atoms, one oxygen atom, and one nitrogen atom. It has been shown to be an effective treatment for wastewater by removing nitrogen and phosphorus. Dithiooxamide binds to metal ions such as copper and iron in the water, forming a complex. This process prevents the metal ions from being available as catalysts in the oxidation of organic pollutants. The binding of dithiooxamide with these metals also removes them from wastewater, preventing them from being taken up by plants or animals. Dithiooxamide can be used to remove malonic acid (a carcinogen) and p-nitrophenyl phosphate (a liver toxin) from blood samples for analysis using electrochemical impedance spectroscopy, which relies on the ability of dithiooxamide to bind to these chemicals. Dithiooxamide is also used as a surfactant in analytical chemistry methods such as gas chromatography or liquid chromatography because it</p>

<p>Please enquire for more information about Gly-arg-4-methoxy-beta-naphthylamide dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(Aminomethyl)-N,N-dimethyl-1,2,4-oxadiazole-5-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>NIR-664 is a potential use for the treatment of cancer. It is an iodinated acetamide with a ruthenium complex that has been shown to have magnetic and fluorescent properties. The diameter of NIR-664 is approximately 2 nm, and it has a hydrophobic character. This compound can be used in nanocrystals or as a mesoporous material. The fluorescence of NIR-664 can be observed in the near infrared region at 664 nm, which gives this compound its name. NIR-664 has also been shown to react with ruthenium, which makes it suitable for use in particle form.</p>

<p>N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide is a novel glycol ester with cytotoxic effects. It has been shown to inhibit the growth of cancer cells in rat liver microsomes and in vivo. N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide inhibits the synthesis of fatty acids by inhibiting the enzyme lipoxygenase. This drug also has a reactive carbon nanotube that may be used as an anticancer agent, which can bind to cell membranes and disrupt their function.</p>

<p>Please enquire for more information about N-Propyl-N-(2,3-epoxypropyl)perfluoro-n-octylsulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Glucagon-like peptide 1 (7-36) amide is a peptide hormone produced by the ileum and colon of the small intestine in response to food intake. It stimulates insulin release from the pancreas, inhibits glucagon secretion, and slows gastric emptying. GLP-1 is also a potent regulator of glucose homeostasis. The GLP-1 analogues are used for treatment of type 2 diabetes mellitus. These analogues are either injected or taken orally and mimic the effect of natural GLP-1 on blood sugar regulation and appetite control. The long duration of action means that daily injections or multiple oral doses are required to maintain therapeutic levels.</p>