Amides

<p>Inducer of apoptosis; down-regulated in tumors</p>

<p>2-Chloroacetamide is a quaternary ammonium compound that is used as an intermediate in the synthesis of other organic compounds. It has been reported to have anticancer activity and has been studied for use as a herbicide in agriculture. The vibrational, turbidimetric method, amide, and sample preparation are all instrumental in determining the reaction mechanism of 2-chloroacetamide. This molecule has also been studied using FT-IR spectroscopy and molecular modelling techniques. The hydrogen bond is integral to its optical properties and can be determined by nmr spectra.</p>

<p>Dynorphin A (1-10) amide H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-NH2 is an analog of dynorphin A. It is a peptide that has been shown to be effective in reducing blood pressure and stress levels in animals. Dynorphin A (1-10) amide H-Tyr-Gly-Gly-Phe-Leu-Arg - Arg - Ile - Arg - Pro - NH2 also has analgesic properties and may be useful for the treatment of cardiac diseases.</p>

<p>Please enquire for more information about TRAP-5 amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-[(4-Chloro-2-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutanamide is a chelating agent that has been used as a control agent in the manufacture of dyes, plastics, and rubber. It is also used as an additive in paints, textiles, and paper. 2-[(4-Chloro-2-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutanamide is nonvolatile, nonflammable, and does not produce toxic byproducts when heated. This compound has low molecular weight with a molecular formula of C12H13NO5Cl. The structure of this compound includes two hydroxy groups (OH), one aliphatic hydrocarbon group (CH3), one carboxylic acid group (COOH), and three chlorine atoms (Cl). This product is soluble in water</p>

<p>Please enquire for more information about HSV-1-amide UL 26 Open Reading Frame (242-255) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Leu-Enkephalin amide acetate salt H-Tyr-Gly-Gly-Phe-Leu-NH2 acetate salt is a peptide that is used as an analgesic and antipyretic drug. It is a synthetic form of endogenous enkephalins, which are natural pain relievers. The chemical stability of Leu-Enkephalin amide acetate salt H-Tyr-Gly-Gly-Phe-Leu-NH2 acetate salt makes it an effective drug for chronic use, and it has been shown to have a low side effect profile. This compound also has been shown to block the synthesis of histamine in vivo, but its bioavailability in vivo is not high due to its rapid degradation by proteases.</p>

<p>N-3,5-Dimethyladamantan-1-yl formamide is a hydrocarbon that is synthesized by the amination of 3,5-dimethyladamantane with formic acid in the presence of hydrochloric acid. It is used as a solvent for various chemical reactions and has been shown to be an effective catalyst for the reduction of nitrobenzene to aniline. N-3,5-Dimethyladamantan-1-yl formamide is also a pollutant that can cause environmental pollution when it reacts with chlorine in the atmosphere. The reaction time can be shortened by using acetonitrile as a solvent instead of water.</p>

<p>Please enquire for more information about (D-Trp6)-LHRH (1-6) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Dynorphin A (1-13) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(4-Chlorophenyl)-2-cyanoacetamide is a pyridine compound that can be synthesized from chloroacetonitrile and acetamide. It has been shown to react with an active methylene group in benzene or pyridine to produce a heterocycle. This reaction is reversible and can be used as a preparative method for the synthesis of heterocycles. The 1,3-dipolar cycloaddition of N-(4-chlorophenyl)-2-cyanoacetamide with nitro groups in nitrobenzene produces the corresponding 2-nitropyridines, which are important intermediates in the synthesis of other heterocycles. N-(4-Chlorophenyl)-2-cyanoacetamide has been used as an efficient method for the preparation of nitrogen nucleophiles that are useful for catalysis.</p>

<p>Please enquire for more information about GLP-1 (1-36) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PAR-2 agonist is a synthetic peptide that activates PAR-2. It binds to PAR-2 receptors, which are present in the mesenteric vasculature and in various other tissues. Activation of PAR-2 leads to an increase in intracellular calcium concentration, activation of protein kinase C, cytosolic calcium ion release, phosphorylation of myosin light chain, muscle cell proliferation, transcription and translation initiation, and increased production of vasoactive intestinal peptide. This drug also has anti-inflammatory effects and stimulates epidermal growth factor (EGF) and thrombin receptor expression as well as growth factor production.</p>

<p>Please enquire for more information about N-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-Me-Abz-Amyloid beta/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Intermediate in the synthesis of lenvatinib</p>

<p>Please enquire for more information about PAR-2 (1-6) amide (human) (scrambled) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Beta-Casomorphin (1-5) amide (bovine) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PAR-2 (1-6) amide (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val-NH2 trifluoroacetate salt is a protease inhibitor that inhibits the activity of PAR2, a protein receptor. PAR2 is implicated in cancer and inflammation. It has been shown to inhibit growth factor signaling, as well as activate toll-like receptor 4 and other inflammatory pathways. PAR2 inhibition has also been studied in vivo and found to be effective in treating wild type mice with melanoma cells. In vitro studies have shown that PAR2 inhibition by PAR 2 (1-6) amide (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val NH2 trifluoroacetate salt blocks the production of tumour necrosis factor alpha and interleukin 6.</p>

<p>N-alpha-Benzoyl-L-argininamide is a synthetic compound that is used as an enzyme inhibitor. It binds to the active site of proteases, thereby inhibiting their activity. This drug has been shown to inhibit the activities of phosphodiesterase and phosphatase enzymes in vitro. N-alpha-Benzoyl-L-argininamide also inhibits the proteolytic degradation of hippuric acid and casein in vitro. The binding affinity for this drug is due to its structural similarity with substrates such as glutamate and rhizosphere exudates.</p>

<p>N1-Glutathionyl-spermidine disulfide (N1-GS) is a molecule that has been shown to have clinical use in the treatment of chronic hepatitis C infection. The N1-GS molecule is composed of a glutathione (GSH) scaffold with two sulfhydryl groups and an amino acid side chain. N1-GS has a hydrophobic nature, which allows it to penetrate the cellular membrane and enter cells. It is also able to form hydrogen bonds and act as a catalyst for reactions. Fluorescence analysis revealed that this molecule is selective for disulfides over thiols, amines, or alcohols. Disulfides are very important in biological systems since they can be found in enzymes, proteins, and cellular membranes. The insolubility of the N1-GS molecule makes it difficult to analyze its structure using traditional methods such as gas chromatography or nuclear magnetic resonance spectroscopy. However, fluorescence</p>

<p>Parathyroid hormone-related protein (PTHrP) is a peptide hormone produced by the parathyroid gland that functions as a phosphatase, inhibiting alkaline phosphatase. It also has an inhibitory effect on osteoclastic bone resorption and stimulates osteoblastic bone formation. PTHrP has been shown to be useful in treating osteoporosis and Paget's disease. It also has been used in conjunction with dexamethasone to treat patients with malignancies of the head and neck. PTHrP is an inhibitor of protein kinase A and phosphodiesterases, which are enzymes that regulate cellular processes such as proliferation and differentiation.</p>

<p>N-Methyl-4-oxo-4,5-dihydropyridine-3-carboxamide is a fine chemical that can be used as a reagent or intermediate. It is a versatile building block that can be used in the production of useful scaffolds or useful intermediates. This compound has been shown to react with many different types of chemicals, including alcohols and amines. N-Methyl-4-oxo-4,5-dihydropyridine-3-carboxamide can also be used as a reaction component in the synthesis of diverse compounds.</p>

<p>Please enquire for more information about Apelin-36 (1-16) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a peptide that was generated by incubating β-amyloid with the protease papain. This peptide has been shown to induce population and biochemical changes in cells, including focusing of β-amyloid aggregates. It also induces reactive oxygen species and promotes extracellular protofibril formation. Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a conjugate of acetylated lysine residues and amyloid β-protein that can be used as an anti-amyloid therapeutic. The peptide is characterized by dichroism spectroscopy, which has revealed its specific binding to the fibrils' surface.</p>

<p>Parathyroid hormone (PTH) is a peptide hormone that regulates calcium and phosphate balance in the body. PTH is secreted by the parathyroid glands, located near the thyroid gland in the neck. It is also known as parathormone or parathyrin. The active form of PTH, called pTH (1-34) amide, has been shown to stimulate bone resorption and to inhibit bone formation. The amino acid sequence of this hormone starts with arginine and ends with phenylalanine. The N-terminal amino acid residue is an aspartic acid or asparagine and histidine is the only basic residue in this molecule. This molecule has two acidic residues, glutamic acid and aspartic acid, which are found on the side chains of two amino acids: aspartic acid and glutamic acid. Valine is found at position 3 and phenylalanine at position 34.</p>

<p>Please enquire for more information about PAR-2 (6-1) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sieber Amide Resin is a glycopeptide that has been shown to inhibit the growth of prostate cancer cells. It inhibits the production of epidermal growth factor and amide, serine protease, and growth factors by binding to their receptors on the cell surface. This drug also has antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus, Streptococcus pyogenes, and Bacillus subtilis. The chemical diversity of Sieber Amide Resin allows it to be used as an intermediate in the synthesis of other pharmaceutically active compounds. The pharmacokinetic properties of this drug allow it to be administered orally or intravenously. The nmr spectra show that this drug is a cyclic peptide with an amide bond between amino acid residues Ser-11 and Gly-12.</p>

<p>Please enquire for more information about Benzenesulfonamide,3-hydrazino- including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cefpiramide sodium is a cephalosporin antibiotic that has been shown to be effective against a wide range of bacteria, including those which are resistant to other antibiotics. Cefpiramide sodium is used for the treatment of skin and soft tissue infections in infants or for the treatment of respiratory tract infections in adults. The antibiotic binds to bacterial cell membranes and inhibits bacterial growth by inhibiting fatty acid synthesis, which is important for the production of cell walls. Cefpiramide sodium has been shown to have antiviral properties as well as antibacterial properties. These effects may be due to its ability to inhibit viral protein synthesis or by binding directly to the virus itself. Cefpiramide Sodium is an anti-infective drug that belongs to a group called cephalosporins, which are antibiotics that inhibit growth of bacteria by binding to their cell walls and preventing them from synthesizing essential fatty acids required for building their cell walls. It also has antiviral properties.</p>

<p>Please enquire for more information about N-[5-[5-(2-Methyl-1-oxoisoindolin-5-yl)thien-2-yl]pyridin-3-yl]-2-nitrobenzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Isoleucine beta-naphthylamide is an amide derivative of L-isoleucine and 2-naphthylamine, which are carboxylic acid derivatives. The condensation of these two substances leads to the formation of a new compound with a carboxy group and an amino group.</p>

<p>6-Ethoxy-2-benzothiazolesulfonamide is a drug that inhibits carbonic anhydrase, which is an enzyme that catalyzes the conversion of carbon dioxide and water to bicarbonate and hydrogen ions. This drug has been shown to be effective for the treatment of bowel disease in animal models. 6-Ethoxy-2-benzothiazolesulfonamide has also been shown to have inhibitory properties against carbonic anhydrase, which may lead to problems with dehydration.</p>

<p>Please enquire for more information about N-(3-Aminopropyl)-2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>tert-Butylsulfinamide is a model system for the synthesis of enantiopure amines and esters. The synthesis of tert-butylsulfinamide starts with the reaction of an allyl bromide with a sulfinic acid chloride to form an allyl sulfonate, which is then hydrolyzed to produce tert-butylsulfinamide. The yield for this type of reaction is usually low, but tert-butylsulfinamide can be isolated in good yields if it is prepared in a stereoselective manner. Tert-butylsulfinamide has been shown to inhibit the growth of human hair follicles in cell culture experiments, which may be due to its ability to inhibit the formation of hydrogen peroxide by inhibiting an enzyme called tyrosine hydroxylase.</p>

<p>Please enquire for more information about 3-(Aminomethyl)-N,N-dimethyl-1,2,4-oxadiazole-5-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Gly-arg-4-methoxy-beta-naphthylamide dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(5-Aminopentyl) methotrexate amide-LC-biotin is a specialized bioconjugate, derived through the conjugation of methotrexate, an established antifolate drug, with an LC-biotin moiety. This product is synthesized by covalently linking methotrexate, which is known for its role in cancer therapy through the inhibition of dihydrofolate reductase (DHFR), to a biotin moiety via a long-chain spacer. The resultant bioconjugate retains the therapeutic effects of methotrexate, particularly in its ability to interrupt nucleotide synthesis, thereby affecting cell division in rapidly proliferating cancer cells.The inclusion of biotin in the structure allows for facile attachment to avidin or streptavidin-labeled systems, facilitating targeted delivery and enhanced detection in molecular and cellular studies. The primary application of N-(5-Aminopentyl) methotrexate amide-LC-biotin lies in the realm of targeted drug delivery and advanced research into methotrexate metabolism. By leveraging the high affinity of biotin-streptavidin interactions, researchers can effectively study the biodistribution and cellular uptake of methotrexate, advancing cancer therapeutic strategies and providing insights into antifolate drug mechanisms at the molecular level.</p>

<p>Dithiooxamide is a chemical compound that contains two sulfur atoms, one oxygen atom, and one nitrogen atom. It has been shown to be an effective treatment for wastewater by removing nitrogen and phosphorus. Dithiooxamide binds to metal ions such as copper and iron in the water, forming a complex. This process prevents the metal ions from being available as catalysts in the oxidation of organic pollutants. The binding of dithiooxamide with these metals also removes them from wastewater, preventing them from being taken up by plants or animals. Dithiooxamide can be used to remove malonic acid (a carcinogen) and p-nitrophenyl phosphate (a liver toxin) from blood samples for analysis using electrochemical impedance spectroscopy, which relies on the ability of dithiooxamide to bind to these chemicals. Dithiooxamide is also used as a surfactant in analytical chemistry methods such as gas chromatography or liquid chromatography because it</p>

<p>N,N-Dimethylformamide dineopentyl acetal (DMFD) is a synthetic drug that has been used to treat cancer and infectious diseases. It is synthesized from the reaction of dimethylformamide with diethylacetal. DMFD has shown an anti-inflammatory effect in animals, which may be due to its ability to inhibit the production of prostaglandins. The structural analysis of DMFD reveals the presence of two phenyl groups and a hydroxyl group, which are responsible for its biological activity. Structural analysis also led to the determination of several functional groups, including a chloride ion and a methoxy group.</p>

<p>NIR-664 is a potential use for the treatment of cancer. It is an iodinated acetamide with a ruthenium complex that has been shown to have magnetic and fluorescent properties. The diameter of NIR-664 is approximately 2 nm, and it has a hydrophobic character. This compound can be used in nanocrystals or as a mesoporous material. The fluorescence of NIR-664 can be observed in the near infrared region at 664 nm, which gives this compound its name. NIR-664 has also been shown to react with ruthenium, which makes it suitable for use in particle form.</p>

<p>N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide is a novel glycol ester with cytotoxic effects. It has been shown to inhibit the growth of cancer cells in rat liver microsomes and in vivo. N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide inhibits the synthesis of fatty acids by inhibiting the enzyme lipoxygenase. This drug also has a reactive carbon nanotube that may be used as an anticancer agent, which can bind to cell membranes and disrupt their function.</p>

<p>Please enquire for more information about N-Propyl-N-(2,3-epoxypropyl)perfluoro-n-octylsulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Glucagon-like peptide 1 (7-36) amide is a peptide hormone produced by the ileum and colon of the small intestine in response to food intake. It stimulates insulin release from the pancreas, inhibits glucagon secretion, and slows gastric emptying. GLP-1 is also a potent regulator of glucose homeostasis. The GLP-1 analogues are used for treatment of type 2 diabetes mellitus. These analogues are either injected or taken orally and mimic the effect of natural GLP-1 on blood sugar regulation and appetite control. The long duration of action means that daily injections or multiple oral doses are required to maintain therapeutic levels.</p>