Amides

<p>2-Chloroacetamide is a quaternary ammonium compound that is used as an intermediate in the synthesis of other organic compounds. It has been reported to have anticancer activity and has been studied for use as a herbicide in agriculture. The vibrational, turbidimetric method, amide, and sample preparation are all instrumental in determining the reaction mechanism of 2-chloroacetamide. This molecule has also been studied using FT-IR spectroscopy and molecular modelling techniques. The hydrogen bond is integral to its optical properties and can be determined by nmr spectra.</p>

<p>Please enquire for more information about (D-Trp6)-LHRH (1-6) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Chloro-3-nitrobenzenesulfonamide is a fluorogenic probe that can be used in the diagnosis of cancer. It inhibits the activity of MCL-1, which is an antiapoptotic protein. The skeleton of 4-Chloro-3-nitrobenzenesulfonamide has been shown to have carbonic and fluorescence properties. This chemical compound is also metabolized by azobenzene to form a fluorescent derivative that can be used for optical imaging in vivo.</p>

<p>Please enquire for more information about Amyloid b-Protein (1-40) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(4-Chlorophenyl)-2-cyanoacetamide is a pyridine compound that can be synthesized from chloroacetonitrile and acetamide. It has been shown to react with an active methylene group in benzene or pyridine to produce a heterocycle. This reaction is reversible and can be used as a preparative method for the synthesis of heterocycles. The 1,3-dipolar cycloaddition of N-(4-chlorophenyl)-2-cyanoacetamide with nitro groups in nitrobenzene produces the corresponding 2-nitropyridines, which are important intermediates in the synthesis of other heterocycles. N-(4-Chlorophenyl)-2-cyanoacetamide has been used as an efficient method for the preparation of nitrogen nucleophiles that are useful for catalysis.</p>

<p>Please enquire for more information about 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Galanin Message Associated Peptide (44-59) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about PAR-3 (1-6) amide (mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sodium dicyanamide is a diphenyl ether that has been shown to be effective in the treatment of polycystic ovarian syndrome. It binds to picolinic acid, which is a cofactor for the enzyme phenylalanine hydroxylase, and inhibits the production of tyrosine. This leads to an increase in the levels of luteinizing hormone and follicle-stimulating hormone, which helps ovulation. Sodium dicyanamide also interacts with hydrogen bond interactions and chelate ligands. The reaction mechanism of this compound is not well understood, but it is known that it can react with oxygen at high temperatures.</p>

<p>L-trans-Epoxysuccinyl-Ile-Pro-OMe propylamide is a pharmacological agent that inhibits the toll-like receptor 4 signaling pathway. L-trans-Epoxysuccinyl-Ile-Pro-OMe propylamide has been shown to cause caspase independent cell death by inducing cathepsin and iron homeostasis. The drug also causes polymerase chain reaction inhibition and neuronal death in vivo.</p>

<p>Intermediate in the synthesis of lenvatinib</p>

<p>Ceramide is a fatty acid that is an important component of cell membranes. It has been shown to inhibit the activity of enzymes such as phospholipase A2 and lipoxygenase, which are involved in inflammatory reactions. Ceramide can also be used to diagnose infectious diseases, such as tuberculosis and malaria. The diagnostic procedure involves measuring the enzyme activities of ceramidase and lysosomal sphingomyelinase with the help of a radioactive substrate. This can be done by extracting tissue from mammalian cells or by drawing blood samples from patients. In addition, ceramide may be associated with insulin resistance and cancer.</p>

<p>Inducer of apoptosis; down-regulated in tumors</p>

<p>4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4AFBDS) is a chemical compound that can be used for the treatment of wastewater. It has shown to be effective against anhydrase, which is an enzyme that catalyzes the conversion of water to hydrogen peroxide and hydroxide ion. 4AFBDS also attenuates oxidative stress in cardiac cells and inhibits the production of active oxygen species by inhibiting the activity of carbonic anhydrase. The chromatographic method used to detect 4AFBDS was found to be more sensitive than a standard colorimetric assay, making it a better tool for detecting this compound in wastewater samples. br&gt; br&gt; br&gt; br&gt; br&gt; This compound has been shown to have inhibitory effects on e3 ubiquitin ligase, which plays a role in protein degradation via aut</p>

<p>4-Amino-6-chloro-1,3-benzenedisulfonamide is a natural substance that has been used in Chinese medicine preparations for the treatment of cardiac problems. It belongs to the class of organic compounds called benzenedisulfonamides. 4-Amino-6-chloro-1,3-benzenedisulfonamide is produced by the bacterial enzyme aminase from amino acid and benzoic acid. The adsorption mechanism of 4-Amino-6-chloro-1,3-benzenedisulfonamide is not fully understood, but it is believed that the benzyl groups are key players in this process. The high affinity of 4-Amino-6-chloro1,3 benzenedisulfonamide to proteins may be due to its ability to form hydrogen bonds with protein side chains, such as serine or threonine residues. 4 Amino</p>

<p>Please enquire for more information about Amyloid P Component (33-38) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PAR-2 (1-6) amide (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val-NH2 trifluoroacetate salt is a protease inhibitor that inhibits the activity of PAR2, a protein receptor. PAR2 is implicated in cancer and inflammation. It has been shown to inhibit growth factor signaling, as well as activate toll-like receptor 4 and other inflammatory pathways. PAR2 inhibition has also been studied in vivo and found to be effective in treating wild type mice with melanoma cells. In vitro studies have shown that PAR2 inhibition by PAR 2 (1-6) amide (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val NH2 trifluoroacetate salt blocks the production of tumour necrosis factor alpha and interleukin 6.</p>

<p>Clopamide is a diuretic drug that belongs to the group of protein genes. It is used in the treatment of chronic heart failure, low-density lipoprotein cholesterol and infectious diseases. Clopamide has been shown to increase the glomerular filtration rate by inhibiting the sodium citrate enzyme, which is involved in the formation of urine from blood plasma. This drug also reduces blood pressure by blocking angiotensin II receptors on vascular smooth muscle cells. Clopamide does not have any significant interactions with other drugs, although caution should be exercised when using it with cardiac drugs due to its effects on blood pressure.</p>

<p>Salicylamide is a drug that is used as an analgesic, antipyretic, and anti-inflammatory agent. It is also used to treat bowel disease, including ulcerative colitis and Crohn's disease. Salicylamide has been shown to inhibit the activity of enzymes such as cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), which are responsible for the production of inflammatory mediators. Salicylamide also inhibits copper chloride induced synchronous fluorescence in rat colon cells. Salicylamide also binds to human serum albumin and other nitrogen atoms, which can be measured using chemiluminescence methods. Salicylamide may also have properties that make it useful for the detection of cancerous tumors in the colon. Salicylamide can be detected using electrochemical impedance spectroscopy by measuring its resistance at different frequencies when a voltage is applied across a cell containing sal</p>

<p>2,2-Dimethylpropionamide is a synthetic chemical that has been shown to have cytotoxic and biochemical properties. It has been tested on leukemia cells (K562) and has been shown to inhibit the bcr-abl kinase. 2,2-Dimethylpropionamide has also been shown to inhibit the production of amide radicals in human serum under constant pressure. The structure of this compound was solved using X-ray diffraction data.</p>

<p>Please enquire for more information about Galanin Message Associated Peptide (25-41) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Kemptamide is a peptide that has been shown to have cytotoxic and anti-proliferative effects on renal cancer cells. It is a synthetic analogue of an endogenous peptide, Lys-Lys-Arg-Pro-Gln-Arg-Ala-Thr-Ser-Asn-Val-Phe, that is found in porcine kidney. Kemptamide’s cytotoxic activity may be due to its ability to inhibit the activity of phosphatases. Kemptamide also has regulatory properties and can modulate the expression of genes that are involved in cell growth and apoptosis. This peptide has been shown to be reactive with kidney cells, which may lead to its therapeutic effect on renal cancer.</p>

<p>PAR-2 agonist is a synthetic peptide that activates PAR-2. It binds to PAR-2 receptors, which are present in the mesenteric vasculature and in various other tissues. Activation of PAR-2 leads to an increase in intracellular calcium concentration, activation of protein kinase C, cytosolic calcium ion release, phosphorylation of myosin light chain, muscle cell proliferation, transcription and translation initiation, and increased production of vasoactive intestinal peptide. This drug also has anti-inflammatory effects and stimulates epidermal growth factor (EGF) and thrombin receptor expression as well as growth factor production.</p>

<p>Please enquire for more information about (Des-His1,Glu9)-Glucagon (1-29) amide (human, rat, porcine) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Nazumamide A is a cyclic peptide with inhibitory activity against serine proteases. It binds to the active site of thrombin and inhibits its action, thereby inhibiting the fibrinogen degradation in blood. Nazumamide A is also found to have neuroprotective properties, which may be due to its ability to inhibit nitric oxide production by binding to the enzyme nitric oxide synthase. It has been shown to have anti-inflammatory activities and can be used for the treatment of inflammation-associated diseases such as asthma and arthritis. Nazumamide A is a nonribosomal peptide that does not require any cofactors for synthesis.</p>

<p>Please enquire for more information about Phenylacetyl-(D-Arg2·28,p-chloro-Phe6, Homoarg 9·29,Tyr(Me)10, Abu 15, Nle 27)-GRF (1-29) amide (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (D-2-Nal 5,Cys6·11,Tyr7,D-Trp8,Val10, 2-Nal 12)-Somatostatin-14 (5-12) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about LHRH (1-6) amide Pyr-His-Trp-Ser-Tyr-Gly-NH2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(3-Dimethylaminopropyl)acrylamide is a polymerization initiator that is used in the synthesis of polymers. It is also a model protein, which can be used to study bacterial growth rates and tissue metabolism. N-(3-Dimethylaminopropyl)acrylamide has been shown to have biological properties similar to human serum, as well as to serve as a model for primary cells. The FT-IR spectroscopy of N-(3-Dimethylaminopropyl)acrylamide reveals the presence of chloride ions in its molecular structure. The reaction mechanism for this compound has been determined by deionized water and ionic reactions with chloride ions.</p>

<p>4-Biphenylac-Cys(Me)-D-Arg-Phe-(2-phenylethyl)amide is a tetrapeptide that has been shown to have antihypertensive properties. This drug binds to the regulatory proteins of the renin angiotensin system and blocks the production of angiotensin II, which decreases blood pressure. 4-Biphenylac-Cys(Me)-D-Arg-Phe-(2-phenylethyl)amide has also shown to be an effective treatment for skin care products, especially those used for inflammatory skin diseases. 4-Biphenylac-Cys(Me)-D-Arg-Phe-(2-phenylethyl)amide has been shown to be a potent inhibitor of serine proteases and can inhibit cellular proliferation and induce apoptosis in cancer cells.</p>

<p>Please enquire for more information about PAR-3 (1-6) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Syndyphalin SD-33 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Protease-activated receptor 1 (PAR-1) selective activating peptide, TFA salt. 98%.</p>

<p>Please enquire for more information about 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Cys18)-Atrial Natriuretic Factor (4-18) amide (mouse, rabbit, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methylsalicylamide is a chemical compound that belongs to the class of isonicotinic amides. It is a potent anti-inflammatory agent with minimal inhibitory concentration (MIC) values of 4 µg/mL for gram-positive bacteria and 8 µg/mL for gram-negative bacteria. This compound has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. 4-Methylsalicylamide has been shown to have an inhibitory effect on ring-opening, which may be due to its ability to acetylate mitochondrial membranes, altering the membrane potential. The molecular modeling studies also showed that 4MSAM binds at the same site as antibiotics such as penicillin and erythromycin in bacterial ribos</p>

<p>Glycinamide hydrochloride is an inhibitor that binds to the glycine-binding site of the protein synthetase and inhibits the formation of glycinamide ribonucleotide. It has been shown to inhibit human glycinamide ribonucleotide synthetase in vitro. Glycinamide hydrochloride is also a glycinamide amide, which was synthesized by linking two molecules of glycine with an amide bond. This molecule is cross-linked with a macrogel, forming a hydrogel. The hydrogel can be used in biomedical applications, such as tissue engineering and drug delivery systems.</p>

<p>Sieber Amide Resin is a glycopeptide that has been shown to inhibit the growth of prostate cancer cells. It inhibits the production of epidermal growth factor and amide, serine protease, and growth factors by binding to their receptors on the cell surface. This drug also has antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus, Streptococcus pyogenes, and Bacillus subtilis. The chemical diversity of Sieber Amide Resin allows it to be used as an intermediate in the synthesis of other pharmaceutically active compounds. The pharmacokinetic properties of this drug allow it to be administered orally or intravenously. The nmr spectra show that this drug is a cyclic peptide with an amide bond between amino acid residues Ser-11 and Gly-12.</p>

<p>Please enquire for more information about Benzenesulfonamide,3-hydrazino- including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-[5-[5-(2-Methyl-1-oxoisoindolin-5-yl)thien-2-yl]pyridin-3-yl]-2-nitrobenzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cefpiramide sodium is a cephalosporin antibiotic that has been shown to be effective against a wide range of bacteria, including those which are resistant to other antibiotics. Cefpiramide sodium is used for the treatment of skin and soft tissue infections in infants or for the treatment of respiratory tract infections in adults. The antibiotic binds to bacterial cell membranes and inhibits bacterial growth by inhibiting fatty acid synthesis, which is important for the production of cell walls. Cefpiramide sodium has been shown to have antiviral properties as well as antibacterial properties. These effects may be due to its ability to inhibit viral protein synthesis or by binding directly to the virus itself. Cefpiramide Sodium is an anti-infective drug that belongs to a group called cephalosporins, which are antibiotics that inhibit growth of bacteria by binding to their cell walls and preventing them from synthesizing essential fatty acids required for building their cell walls. It also has antiviral properties.</p>

<p>L-Isoleucine beta-naphthylamide is an amide derivative of L-isoleucine and 2-naphthylamine, which are carboxylic acid derivatives. The condensation of these two substances leads to the formation of a new compound with a carboxy group and an amino group.</p>

<p>6-Ethoxy-2-benzothiazolesulfonamide is a drug that inhibits carbonic anhydrase, which is an enzyme that catalyzes the conversion of carbon dioxide and water to bicarbonate and hydrogen ions. This drug has been shown to be effective for the treatment of bowel disease in animal models. 6-Ethoxy-2-benzothiazolesulfonamide has also been shown to have inhibitory properties against carbonic anhydrase, which may lead to problems with dehydration.</p>

<p>Please enquire for more information about N-(3-Aminopropyl)-2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>tert-Butylsulfinamide is a model system for the synthesis of enantiopure amines and esters. The synthesis of tert-butylsulfinamide starts with the reaction of an allyl bromide with a sulfinic acid chloride to form an allyl sulfonate, which is then hydrolyzed to produce tert-butylsulfinamide. The yield for this type of reaction is usually low, but tert-butylsulfinamide can be isolated in good yields if it is prepared in a stereoselective manner. Tert-butylsulfinamide has been shown to inhibit the growth of human hair follicles in cell culture experiments, which may be due to its ability to inhibit the formation of hydrogen peroxide by inhibiting an enzyme called tyrosine hydroxylase.</p>

<p>N,N-Dimethylformamide dineopentyl acetal (DMFD) is a synthetic drug that has been used to treat cancer and infectious diseases. It is synthesized from the reaction of dimethylformamide with diethylacetal. DMFD has shown an anti-inflammatory effect in animals, which may be due to its ability to inhibit the production of prostaglandins. The structural analysis of DMFD reveals the presence of two phenyl groups and a hydroxyl group, which are responsible for its biological activity. Structural analysis also led to the determination of several functional groups, including a chloride ion and a methoxy group.</p>

<p>N-(5-Aminopentyl) methotrexate amide-LC-biotin is a specialized bioconjugate, derived through the conjugation of methotrexate, an established antifolate drug, with an LC-biotin moiety. This product is synthesized by covalently linking methotrexate, which is known for its role in cancer therapy through the inhibition of dihydrofolate reductase (DHFR), to a biotin moiety via a long-chain spacer. The resultant bioconjugate retains the therapeutic effects of methotrexate, particularly in its ability to interrupt nucleotide synthesis, thereby affecting cell division in rapidly proliferating cancer cells.The inclusion of biotin in the structure allows for facile attachment to avidin or streptavidin-labeled systems, facilitating targeted delivery and enhanced detection in molecular and cellular studies. The primary application of N-(5-Aminopentyl) methotrexate amide-LC-biotin lies in the realm of targeted drug delivery and advanced research into methotrexate metabolism. By leveraging the high affinity of biotin-streptavidin interactions, researchers can effectively study the biodistribution and cellular uptake of methotrexate, advancing cancer therapeutic strategies and providing insights into antifolate drug mechanisms at the molecular level.</p>

<p>Dithiooxamide is a chemical compound that contains two sulfur atoms, one oxygen atom, and one nitrogen atom. It has been shown to be an effective treatment for wastewater by removing nitrogen and phosphorus. Dithiooxamide binds to metal ions such as copper and iron in the water, forming a complex. This process prevents the metal ions from being available as catalysts in the oxidation of organic pollutants. The binding of dithiooxamide with these metals also removes them from wastewater, preventing them from being taken up by plants or animals. Dithiooxamide can be used to remove malonic acid (a carcinogen) and p-nitrophenyl phosphate (a liver toxin) from blood samples for analysis using electrochemical impedance spectroscopy, which relies on the ability of dithiooxamide to bind to these chemicals. Dithiooxamide is also used as a surfactant in analytical chemistry methods such as gas chromatography or liquid chromatography because it</p>

<p>Please enquire for more information about 3-(Aminomethyl)-N,N-dimethyl-1,2,4-oxadiazole-5-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Gly-arg-4-methoxy-beta-naphthylamide dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>NIR-664 is a potential use for the treatment of cancer. It is an iodinated acetamide with a ruthenium complex that has been shown to have magnetic and fluorescent properties. The diameter of NIR-664 is approximately 2 nm, and it has a hydrophobic character. This compound can be used in nanocrystals or as a mesoporous material. The fluorescence of NIR-664 can be observed in the near infrared region at 664 nm, which gives this compound its name. NIR-664 has also been shown to react with ruthenium, which makes it suitable for use in particle form.</p>

<p>N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide is a novel glycol ester with cytotoxic effects. It has been shown to inhibit the growth of cancer cells in rat liver microsomes and in vivo. N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide inhibits the synthesis of fatty acids by inhibiting the enzyme lipoxygenase. This drug also has a reactive carbon nanotube that may be used as an anticancer agent, which can bind to cell membranes and disrupt their function.</p>

<p>2-Chloro-N-(4-methoxyphenyl)propanamide (2CMPP) is an acetanilide with a chloro substituent. It is used in research and yields better results than 2-chlorobenzoyl chloride. Acetanilides are prepared by the catalytic reduction of nitrobenzenes or chlorobenzenes with sodium or potassium borohydride in the presence of water. The reaction is exothermic and produces a white solid, which can be purified by recrystallization or column chromatography. Preparative methods for acetanilides include reaction of phenols with acetic anhydride and formaldehyde, followed by hydrolysis of the resulting ester to yield the corresponding amide.</p>

<p>Please enquire for more information about 2-Chloro-N-cyclohexyl-N-phenylpropanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-Propyl-N-(2,3-epoxypropyl)perfluoro-n-octylsulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Glucagon-like peptide 1 (7-36) amide is a peptide hormone produced by the ileum and colon of the small intestine in response to food intake. It stimulates insulin release from the pancreas, inhibits glucagon secretion, and slows gastric emptying. GLP-1 is also a potent regulator of glucose homeostasis. The GLP-1 analogues are used for treatment of type 2 diabetes mellitus. These analogues are either injected or taken orally and mimic the effect of natural GLP-1 on blood sugar regulation and appetite control. The long duration of action means that daily injections or multiple oral doses are required to maintain therapeutic levels.</p>