Amides

<p>Applications 2-tert-Butylbenzenesulfonamide can be used as reactant in preparation of benzimidazole derivatives for inhibiting neoplastic cells.<br>References Sperl, G., et al.: U.S., US 6348032 B1 20020219 (2002)<br></p>

<p>Applications N-[1-[3-(2-Ethoxyphenyl)-2,5-dihydro-5-oxo-1,2,4-triazin-6-yl]ethyl]acetamide is an intermediate in the synthesis of Vardenafil (V098001) related compounds.<br>References Olszewska, T., et al.: Tetahedron., 69, 474 (2013);<br></p>

<p>Stability Moisture Sensitive<br>Applications N,N-Dimethylformamide Diethyl Acetal is used as a reagent in the design of EGF-R tyrosine kinase inhibitors. Also used in the synthesis of aminopyridine derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Traxler, P. et al.: J. Med. Chem., 40, 3601 (1997); Cheikh, N. et al.: Tetrahedron, 69, 1234 (2013);<br></p>

<p>Applications 4-(dimethylamino)benzenesulfonamide (cas# 6162-21-6) is a useful research chemical.<br></p>

<p>Applications 4-Ethynyl-N-ethyl-1,8-napthalamide is a chemical reagent used in the synthesis of fluorescent thalidomide and fluorogenic probes.<br>References Kampmann, S. et al.: Tetrahedron 71, 8140 (2015);<br></p>

<p>Stability Hygroscopic<br>Applications is a novel lipid-soluble, thiol-redox antioxidant and heavy metal chelator.<br></p>

<p>Stability Moisture Sensitive<br>Applications N-Phenylbis(trifluoromethanesulfonamide) is used in the enantioselective synthesis of β-amino acids via the Mannich reaction. Used in the synthesis of sphingosine 1-phosphate-1 receptor agonists useful in pharmaceutical application.<br>References Asano, M. et al.: Tetra. Asymm., 24, 449 (2013);<br></p>

<p>Applications Reproduction of Sindbis virus strains sensitive and resistant to 1-adamantanecarboxamide.<br>References Erice, A., et al.: N. Engl. J. Med., 320, 289 (1989), Andronova, V.L., et al.: Bull. Exper. Bio. Med., 129, 74 (2000).<br></p>

<p>Applications N-(2,4-dimethylphenyl)acetamide (cas# 2050-43-3) is a useful research chemical.<br></p>

<p>Applications 2-Isobutyryl-N-phenyl-3-phenylacrylamide is the labeled analogue of 2-Isobutyryl-N-phenyl-3-phenylacrylamide (I781040), an intermediate for the synthesis of Atorvastatin-d5 Sodium Salt (A791753), the labeled analogue of Atorvastatin (A791750) (1,2,3). Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993) (2) Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996) (3) Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>

<p>Applications 2-(2-hydroxyphenyl)acetamide (cas# 22446-40-8) is a useful research chemical.<br></p>

<p>Applications Methacrylamide (cas# 79-39-0) is a useful research chemical.<br></p>

<p>Applications N-(2-aminoethyl)benzamide (cas# 1009-17-2) is a useful research chemical.<br></p>

<p>Applications Pivalimidamide Hydrochloride is used as a reagent in the preparation of 2-alkyl-4-aryltetrahydropyridopyrimidines and 2-alkyl-4-aryl-tetrahydropyrimidoazepines as selective 5-HT2A antagonists.<br>References Shireman, B. T., et al.: Bioorg. Med. Chem. Lett., 18, 2103 (2008);<br></p>

<p>Applications N-(3,4-dimethylphenyl)acetamide (cas# 2198-54-1) is a useful research chemical.<br></p>

<p>Applications Sulfur trioxide N,N-dimethylformamide Complex is a reagent used to prepare aminopyridines which are inhibitors of tetrameric fructose-1,6-bisphosphatase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dang, Q., et al.: J. Med. Chem., 53, 441 (2010); Hebeisen, P., et al.: Bioorg. Med. Chem. Lett., 21, 3237 (2011)<br></p>

<p>Applications N-Cyclopropyl 5-bromonicotinamide<br></p>

<p>Applications 2-Isobutyryl-N-phenyl-3-phenylacrylamide (E/Z mixture) is an intermediate for the synthesis of pyrrole derivatives, which are useful compounds to develop antimicrobial agents (1).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Mohamed, M. S., et al.: Acta Pharm. 59, 145 (2009)<br></p>

<p>Applications 4-Formyl-n-isopropylbenzamide is an metabolite from the oxidation of the anti-neoplastic agent in aqueous solutions.<br>References Swaffar, D., et al.: Drug Metab. Dispos., 20, 632-642 (1992)<br></p>

<p>Applications N-benzyl-2,2-dichloroacetamide (cas# 6063-50-9) is a useful research chemical.<br></p>

<p>Applications 6-chloro-imidazo[2,1-b]thiazole-5-sulfonic acid amide (cas# 112582-89-5) is a useful research chemical.<br></p>

<p>Applications N-(3-Aminopropyl)acetamide Hydrochloride salt is a salt form of N-Acetyl-1,3-propanediamine (A165390), which is an protected intermediate in the synthesis of analogs of Spermidine (S680400), an antineoplastic agent.<br>References Bergeron, R. et al.: J. Med. Chem, 40, 1475 (1997);<br></p>

<p>Deshydroxy bicalutamide is a ligand that has been synthesized to bind to the androgen receptor. It is an antagonist of the androgen receptor. Deshydroxy bicalutamide has been shown to inhibit cancer cell growth in prostate cancer cell lines, which is due to its ability to bind and block the ligand-binding domain of the androgen receptor. Molecular modelling has shown that deshydroxy bicalutamide binds in the hydroxyl group region of the binding site, which blocks it from binding with other ligands such as testosterone. This may lead to decreased levels of testosterone in males, leading to decreased levels of androgens in prostate cancer cells.</p>

<p>Please enquire for more information about N-(p-Hydroxyphenethyl)-N-(3-hydroxy-4-methoxybenzyl)formamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (NZ)-4-chloro-N-[1-[2-(4-nitrophenyl)ethyl]piperidin-2-ylidene]benzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Methylbenzenesulfonamide is a chemical compound that has been shown to induce apoptosis in bladder cancer cells. It is an acid conjugate of the drug 2-methylbenzene-1,4-sulfonamide and it can be used for the treatment of bladder cancer. The compound binds to the apoptosis protein and inhibits its function, leading to cell death. The cytotoxic effects of 2-methylbenzenesulfonamide have been shown in short term toxicity studies in rats. In long term animal studies, this compound showed no adverse effects on the liver or kidneys, but did show some indication of reproductive toxicity. 2-Methylbenzenesulfonamide is not mutagenic and does not affect male fertility when given orally at doses up to 2000 mg/kg body weight for 90 days. 2-Methylbenzenesulfonamide binds to receptors on the surface of cancerous cells and induces apoptosis by inhib</p>

<p>Ceramide is a group of sphingolipids that are found in the outermost layer of cells. Ceramides have been shown to be important for maintaining cell structure and function, as well as regulating cellular processes such as apoptosis, insulin resistance, and inflammation. A ceramide profile can be used to identify an individual's risk for developing certain conditions such as cardiovascular disease, chronic kidney disease, or cancer. In addition to its role in cell biology, ceramide has been shown to increase insulin sensitivity in animals by increasing glucose uptake in adipocytes. Ceramides are also produced by the body from other lipids such as cholesterol or fatty acids. They are found in various tissues and organs including the brain, skin, lungs, and gut.</p>

<p>Please enquire for more information about N,N-bis(2-Chloroethyl) benzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Diazoimidazole-4-carboxamide is an inhibitor of energy metabolism. It was found that dacarbazine, a drug used to treat cancer, and 5-diazoimidazole-4-carboxamide form a reversible complex. The formation of this complex leads to the irreversible inhibition of cellular respiration and cell lysis. This drug has been shown to be effective against malignant melanoma cells in animals and can be used as a photoinitiator for polymerization. 5-Diazoimidazole-4-carboxamide has also been shown to have an inhibitory effect on blood pressure in animals.</p>

<p>4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide is a chemical compound that inhibits the growth of cancer cells by binding to the active site of b-raf and blocking its activity. It has been shown in a pharmacokinetics study that 4-(4-aminophenoxy)(2-pyridyl)]-N-methylcarboxamide is absorbed rapidly through the oral administration, excreted in urine, and eliminated rapidly from the body. The optimal reaction for this drug was found to be at pH 7.0 with an ionic strength of 0.1 M (sodium chloride). This drug also has significant inhibitory activities against human cervical carcinoma and breast cancer cell lines (MDA-MB-231).</p>

<p>Please enquire for more information about N-(tert-Butoxycarbonyl)glycine N'-methoxy-N'-methylamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Benzenesulphonamide is a biologically active compound that has been shown to bind to an integrin receptor, which mediates the attachment of leukocytes to the endothelium. It also binds to a basic protein found in human immunoglobulin. Benzenesulphonamide has been shown to have cytotoxic effects on synchronous fluorescence cells and can be used for the treatment of bowel disease. This drug has also been shown to be toxic in vitro and in vivo, with a moderate acute oral toxicity and low chronic oral toxicity. Benzenesulphonamide has been shown to act as a surfactant by binding with sodium dodecyl sulfate (SDS), which is commonly used in detergents, disinfectants, shampoos, soaps, and other household products. The biological properties of benzenesulphonamide are not well-known due to its low solubility in water.</p>

<p>N-Methoxy-N-methylacetamide is a nucleophilic amide that can be synthesized by the reaction of acetamide with methylmagnesium chloride. It has been used to synthesize an enantiopure derivative of 2-aminopropanol, which is used in the synthesis of potent antitumor agents. N-Methoxy-N-methylacetamide has shown potent anticancer activity in mice and rats. This molecule exhibits a carbonyl group that can act as an enolate, which is a reactive intermediate within chemical reactions. The nucleophilic attack on this carbonyl group leads to intramolecular hydrogen transfer, producing a more stable product.</p>

<p>Please enquire for more information about 4-(2,3-Epoxypropoxy)phenylacetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Amino-5-methoxy-2-methyl-N-methylbenzenesulfonamide is a surfactant that is used in the chemical industry to dissolve diazotized aromatic amines. It is also used in the preparation of coupling agents, such as naphthol, and hydrochloric acid. 4-Amino-5-methoxy-2-methylbenzenesulfonamide can be prepared by the diazotization of aniline followed by coupling with hydrochloric acid and sodium phosphate. The product can then be purified by recrystallization from a salt solution containing sodium acetate.</p>