Carboxylic Acids

<p>Applications 4-tert-Butoxyphenylboronic Acid is a compound used in the preparation of nitrophenylphenol via cross-coupling reaction of nitrohalobenzenes with phenylboronic acids and deprotection.<br>References Kumamoto, N., et al.: Preparation of nitrophenylphenol, JP 2001055360 (2001);<br></p>

<p>Applications Ethyl Acetate (2-13c, 99%) (cas# 58735-82-3) is a useful research chemical. This isotopic compound is used as a tracer in various experiments, for instance, during the conversion of oxygenated and hydrocarbon molecules to particulate matter for fuel purposes, and biosynthesis of terpenes.<br>References Aaron, E., et.al., Combust Flame, 161,2966-2974,(2014); Citron,C., et.al., Chem Comm,50,5224-5226,(2014);<br></p>

<p>Applications 7-Chloro-4-oxo-4H-chromene-2-carboxylic acid (cas# 114741-22-9) is a useful research chemical.<br></p>

<p>Applications 1-Cyclopentenecarboxylic Acid can be used for enantioselective 1,3-dipolar cycloadditions of diazoacetates and solid-phase synthesis of substituted indolines. It can also be used to develop antagonists for A1- and A2-adenosine receptors.<br>References Sibi, M. P., et al.: Org Lett. 9, 1553 (2007); Nicolaou, K. C., et al.: J. Am. Chem. Soc. 122, 2966 (2000); Jacobson, K. A., et al.: Biochem. Pharmacol. 37, 3653 (1988)<br></p>

<p>Stability Air Sensitive<br>Applications (2S)-2-Mercaptopropanoic Acid is an intermediate in synthesizing (R)-(+)-Thiolactomycin (T350880). It is a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).<br>References Kapilashrami, K., et al.: J. Biol. Chem., 288, 6045 (2013); Paneerselvam, V., et al.: J. Pharm. Res., 4, 4618 (2011); Katane, M., et al.: Biochimie, 92, 1371 (2010)<br></p>

<p>Applications A useful synthetic intermediate for the preparation of novel antiinflammatory agents.<br></p>

<p>Applications Phosphoric acid diethyl octyl ester is part of a group of phosphate derivatives that enhance drug penetration through the skin. Phosphoric acid diethyl octyl ester is also used as a reagent to prepare trialkyl phosphate and phosphorothiolate anticholinesterases.<br>References Aoyagi, T., et al.: Drug Des. Discovery, 8, 47 (1991); Bracha, P. &amp; O’Brien, R.: Biochemistry, 7, 1555 (1968)<br></p>

<p>Applications 3,5-Dinitro-o-toluic Acid is used to gather data for partition coefficients of solutes and vapors into anhydrous THF and 1,4-dioxane using Abraham model.<br>References Saifullah, M., et al.: J. Solution Chem., 40, 2082 (2011);<br></p>

<p>Applications Pentachlorophenyl Cyanoacetate is an intermediate used in the synthesis of Cefacetrile (C231500), which is a cephalosporin antibiotic. Antibacterial.<br>References Dajan, A., et al.: Vet. Microbiol., 35, 213 (1993), Becker, M., et al.: Anal. Chim. Acta, 520, 19 (2004), El-Shaboury, S., et al.: J. Pharm. Biomed. Anal., 45, 1 (2007),<br></p>

<p>Applications γ-Isodurylic Acid is an intermediate in the synthesis of Ketoprofen (K200800) related compounds.<br>References Colomina, M., et al.: J. Chem. Thermodynamics., 19, 1139 (1987);<br></p>

<p>Stability Hygroscopic<br>Applications tert-Butyl (((mesityl)sulfonyl)oxy)carbamate is a useful reagent for the enantioselective aziridination of α,β-unsaturated aldehydes.<br>References Arai, H., et l.: Tetrahedron Lett., 50, 3329(2009)<br></p>

<p>Applications 2-Ethylheptanoic Acid is used in the preparation of prostaglandin which is for for promoting bone growth<br>References Barrett, S., et al.: PCT Int. Appl., 331 (2015)<br></p>

<p>Applications Isopropenylboronic Acid Pinacol Ester, can be used as an intermediate in the synthesis of variety of cyclic and acyclic organic compounds. It is also shown that the α-Substituted Allyl/Croty of this compound can be used for highly Diastereo- and Enantioselective allylboration of aldehydes.<br>References Salaun, J. et al.: Topics in Curr. Chem. 1, 144 (1988); Chen, J. et al.: J. Amer. Chem. Soci., 135, 5316 (2013);<br></p>