Carboxylic Acids

<p>Applications N-​Methylaniline Trifluoroacetate is regent used in organic synthesis, functioning as an α-methylating agent for ketones and activates internucleodecoupling upon removal.<br>References Nikolaev, V. et al.: E-Eros. Encyc. Reag. Org. Synth, 1, (2001); Wallace, D. et al.: Tetrahedron Lett., 54, 4425 (2013);<br></p>

<p>Applications Phosphorodichloridic Acid is an intermediate used in the synthesis of Cefotiam Dihydrochloride-13C, 15N2 (C243007), which is labelled Cefotiam Dihydrochloride (C243005), which is an antibiotic product used in injections to treat bacterial infections. Cefotiam Dihydrochloride can also reduce allergic reactions and mixed with pharmaceutical carriers for medical formulations.<br>References Jiang, C., et al.: Faming Zhuanli Shenqing, CN 105646539 A, 20160608 (2016); Liu, X.: Faming Zhuanli Shenqing, CN 105193819 A, 20151230, (2015); Weng, Y., et al.: Faming Zhuanli Shenqing, CN 103601737 A. 20140226 (2014)<br></p>

<p>Applications Ethyl 5-amino-1-benzofuran-2-carboxylate is used as an synthetic intermediate in the preparation of indolebutylpiperazines, a class of dual 5-HT1A receptor agonists and serotonin reuptake inhibitors. Ethyl 5-amino-1-benzofuran-2-carboxylate was also used as a potential radiolabelled analog for melanoma imaging and targeted radiotherapy.<br>References Chezal, J.M., et al.: J. Medn. Chem., 51, 3133 (2008); Heinrich, T., et al.: J. Medn. Chem., 47, 4684 (2004);<br></p>

<p>Applications 2,5-Dimethylthiophene-3-boronic acid<br></p>

<p>Applications Used for preparation of Terfenadine (T114500) analogs.<br>References Uchida., et al.: Chem. Pharm. Bull., 37, 958 (1989),<br></p>

<p>Applications Ethyl 3,4-dihydro-2H-pyran-2-carboxylate (cas# 83568-11-0) is a useful research chemical.<br></p>

<p>Applications 6-Heptynoic Acid is used as a reagent in organic synthesis, inlcuding that of some novel triazole derivatives which display antiproliferative activity and also of acetylenic fatty acids and their esters.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pertino, M., et al.: Molecules, 19, 2523 (2014); Nakatani, M., et al.: B. Chem. Soc. Jpn., 59, 3535 (1986);<br></p>

<p>Applications Methylboronic Acid is a methylated derivative of boronic acid, a building block towards various intermediates in suzuki coupling.<br>References Baker, J. O., et al.: Biochem.. 22, 2098 (1983); Garner, C.W., et al.: J. Biol. Chem., 255, 5064 (1980)<br></p>

<p>Applications 3-((1-Oxo-1-(3-(trimethylsilyl)propoxy)propan-2-yl)thio)propanoic acid is useful reagent for organic reactions and synthesis.<br></p>

<p>Impurity Lubiprostone Impurity VI<br>Applications 7-((1R,2R,3R)-3-(cyclohexylmethoxy)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl)heptanoic Acid is a useful chemical reagent.<br></p>

<p>Applications (+/-)-Nipecotic Acid (cas# 498-95-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,2-Dimethylbutyrate (DMB) is a potential treatment for thalassemia and hemoglobinopathies.<br>References Yeh, K., et al.: J. Pharmacokinet. Biopharm., 6, 79 (1978), Cunningham, M., et al.: Blood, 104, 34 (2004), Rund, D., et al.: N. Engl. J. Med., 353, 1135 (2005),<br></p>