Carboxylic Acids

Applications (8Z,11Z,14Z)-8,11,14-Heptadecatrienoic Acid, is a naturally occurring hydroxylated fatty acid that is found in Acinetobacter species. It acts as a partial agonist of free fatty acid receptor 1 (FFAR1/GPR40) and GPR84 receptors in vitro. It also inhibits bovine hepatic ligase (Ki = 4.4 μM) and mouse kidney mitochondrial medium-chain acyl-CoA synthetase by 48% at a concentration of 40 μM.
References Moss, C.W., et al.: J. Clin. Microbiol. 26(3), 484-492 (1988).; Kaspersen, M.H., et al.: Med. Chem. Commun. 8(6), 1360-1365 (2017).

Applications A reactant used in the preparation of (-)-Amathaspiramide F.
References Sakaguchi, K. et al.: Tetrahedron, 65, 10355 (2009); Sakaguchi, K. et al.: Org. Lett., 10, 5449 (2008)

Applications 2,5-Furandicarboxylic Acid Diethyl Ester (cas# 53662-83-2) is a compound useful in organic synthesis.

Applications 2-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid (cas# 13193-24-3) is a useful research chemical.

Applications Vinblastine N'b-Oxide Maleic Acid Salt is an analog of vinca alkaloid n-oxide that is used for the treatment of hyperproliferative diseases.

Applications Cyclopentylacetic acid is a reagent the synthesis of Cyclopentamine (C988355), which is a vasoconstrictor that acts as a releasing agent of the neurotransmitters norepinephrine, epinephrine and dopamine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schmidt, J.L. et al.: J. Pharmacol. Exp. Ther., 145, 83 (1964); Iversen, L.L.: J. Pharm. Pharmacol., 16, 435 (1964);

Applications 5,6-dibromonicotinic acid (cas# 29241-64-3) is a useful research chemical.

Applications 5-Chloro-2-fluorobenzoic Acid (cas# 394-30-9) is a compound useful in organic synthesis.

Applications 5-carbamoylpentanoic acid (cas# 334-25-8) is a useful research chemical.

Applications Ethyl 4-Chloroacetoacetate (cas# 638-07-3) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-CYCLOPENTYL-2-PHENYLACETIC ACID (cas# 3900-93-4) is a useful research chemical.

Applications Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.
References Ebeling, P., et al.: Lancet, 343, 1479 (1994); Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994); Ramachary, D.B., et al.: RSC Advances, 3, 13497-13506 (2013); Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977);

Applications Used in the preparatiom of esters of 6-aminohexanoic acid as antibacterial agents. EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo xy peptidase, plasmin, and plasminogen activator.
References Dolezal, P., et al.: Pharm. Res., 10, 1015 (1993), Vavrova, K., et al.: Curr. Med. Chem., 12, 2273 (2005), Holas, T., et al.: Bioorg. Med. Chem., 14, 7671 (2006),