Carboxylic Acids

<p>Applications 1,2,4-Benzenetricarboxylic acid 1,2-Dihexyl Ester is a useful reagent for organic synthesis.<br></p>

<p>Applications Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br></p>

<p>Applications 3-ethyladamantane-1-carboxylic acid (cas# 37845-05-9) is a useful research chemical.<br></p>

<p>Applications Isostearic acid is a useful synthetic intermediate. It is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.<br>References Smyth, T., et al.: Appl. Microbio. Biotechnol., 87, 1347 (2010); Anand, M., et al.: J. Phys. Chem. B, 110, 14693 (2006); Hsieh, H., et al.: Langmuir, 26, 10031 (2010); Ashby, R., et al.: Appl. Microbio. Biotechnol., 85, 359 (2009)<br></p>

<p>Applications 4,4'-Dithiobisbenzoic Acid Dimethyl Ester (cas# 35190-68-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid<br></p>

<p>Applications 5-(Benzyloxy)-2-Hydroxybenzoic Acid (cas# 16094-44-3) is a useful research chemical.<br></p>

<p>Applications 1,4-Cubanedicarboxylic acid<br></p>

<p>Applications (E)-2-Thiopheneacrylic Acid is used in the synthesis of anti-HIV HEPT analogs. Also used in the synthesis of benzimidazole and caffeine (C080100) analogs as inhibitors of monoamine oxidase B.<br>References Pontikis, R. et al.: J. Med. Chem., 40, 1845 (1997); van den Berg, D. et al.: Bioorg. Med. Chem., 15, 1692 (2007);<br></p>

<p>Stability Moisture Sensitive, Air Sensitive<br>Applications As-Methyl Arsonothioic Acid is used as a standard for arsenic inspection. It is used as an aid to help in determining the level of toxicity in humans. Metabolite in some mammals and microbiota.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naranmandura, H. et al.: Chem. Res. Toxicol., 24, 1586 (2011); Bu, N. et al.: Metallom., 3, 1064 (2011);<br></p>

<p>Applications 3-((1-Oxo-1-(3-(trimethylsilyl)propoxy)propan-2-yl)thio)propanoic acid is useful reagent for organic reactions and synthesis.<br></p>

<p>Applications (2,5-Dimethylphenyl)boronic Acid is a useful synthetic intermediate. It can be used to prepare fluorenones/indenofluorenediones.<br>References Liu, T., et al.: Org. Lett., 13, 2452 (2011)<br></p>

<p>Stability Air Sensitive<br>Applications Ethyl 2-Mercapto-1-cyclohexenecarboxylate is a reagent used in the synthesis of anti-inflammatory compounds,<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lloret, G. et al.: J. Phys. Org. Chem., 22, 1188 (2009);<br></p>

<p>Applications 5-(aminomethyl)-2-furoic acid hydrochloride (cas# 934-65-6) is a useful research chemical.<br></p>